1-Naphthylamine-4,6,8-trisulfonic acid

Product Name: 1-Naphthylamine-4,6,8-trisulfonic acid
CAS No.: 17894-99-4
Chemical Name: 1-Naphthylamine-4,6,8-trisulfonic acid
Synonyms: 1-NAPHTHYLAMINE-4,6,8-TRISULFONIC ACID;8-aminonaphthalene-1,3,5-trisulfonicaci;8-AMINO-1,3,5-NAPHTHALENETRISULFONIC ACID;8-azanylnaphthalene-1,3,5-trisulfonic acid;8-aminonaphthalene-1,3,5-trisulphonic acid;8-AMINO-NAPHTHALENE-1,3,5-TRISULFONIC ACID;1,3,5-Naphthalenetrisulfonic acid, 8-amino-
CBNumber: CB2201236
Molecular Formula: C10H9NO9S3
Formula Weight: 383.37
MOL File: 17894-99-4.mol

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1-Naphthylamine-4,6,8-trisulfonic acid Property

Density: 1.974±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: -1.75±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CHM0006894
Product name: 1-NAPHTHYLAMINE-4,6,8-TRISULFONIC ACID
Purity: 95.00%
Packaging: 5G
Price: $1127.86
Updated: 2021/12/16

Crysdot

Product number: CD12131218
Product name: 8-Aminonaphthalene-1,3,5-trisulfonicacid
Purity: 95+%
Packaging: 5g
Price: $823
Updated: 2021/12/16

Alichem

Product number: 17894994
Product name: 8-Aminonaphthalene-1,3,5-trisulfonicacid
Packaging: 1g
Price: $1246
Updated: 2021/12/16

Alichem

Product number: 17894994
Product name: 8-Aminonaphthalene-1,3,5-trisulfonicacid
Packaging: 5g
Price: $1917
Updated: 2021/12/16

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1-Naphthylamine-4,6,8-trisulfonic acid Chemical Properties,Usage,Production

Chemical Properties

1-Aminonaphthalene-4,6,8-trisulfonic acid [17894-99-4]. (8-aminonaphthalene1,3,5-trisulfonic acid), B acid, C10H9NO9S3, Mr 383.36, is reduced with zinc and alkali to 1- aminonaphthalene-4,6-disulfonic acid. Heating with aqueous sulfuric acid causes desulfonation to form 1-aminonaphthalene-6,8-disulfonic acid. Sulfonation (25 % oleum, 90℃) gives the sultam of 1-aminonaphthalene-2,4,6,8-tetrasulfonic acid.

Uses

Alkali fusion of B acid yields K acid. A special outlet for purified B acid is in the synthesis of the drug suramin sodium (Bayer 205) . 1-Aminonaphthalene-4,6,8-trisulfonic acid is acylated with 2-nitrotoluyl chloride, and this product is reduced and acylated with mnitrobenzoyl chloride. This intermediate is reduced and finally phosgenated to give suramin sodium, which has been used to treat trypanosomiasis and onchocerciasis.

Production Methods

Naphthalene is sulfonated under conditions that maximize formation of the 1,3,5-trisulfonic acid, followed by nitration with H2SO4– HNO3 in situ at 35℃. After quenching, neutralization with calcium carbonate, and reduction of the nitro-derivative with iron under acid conditions, the byproduct 1- aminonaphthalene-3,6,8-trisulfonic acid (18 % yield) is selectively precipitated by acidification. The desired isomer is then precipitated by further acidification and salting of the filtrates, and finally purified by reprecipitation. Overall yield is 25 – 30 %.

1-Naphthylamine-4,6,8-trisulfonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea

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1-Naphthylamine-4,6,8-trisulfonic acid Suppliers

China 33 Finland 1 United Kingdom 2 United States 15 Global 51

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Fax: +86-25-52131256
Email: 799750417@qq.com
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 18112977050
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ShangHai Biochempartner Co.,Ltd

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Amadis Chemical Company Limited

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Suzhou Hengning Pharmaceutical Technology Co., Ltd.

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Jinan Guoding Pharmaceutical Technology Co., Ltd.

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Alfa Chemistry

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Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
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ProdList: 30239
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Wuhan Ruilida Biomedical Technology Co., Ltd.

Tel: 18201884268
Email: magean83@163.com
Country: China
ProdList: 1541
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BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
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View Lastest Price from 1-Naphthylamine-4,6,8-trisulfonic acid manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 1-Naphthylamine-4,6,8-trisulfonic acid 17894-99-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-19

17894-99-4, 1-Naphthylamine-4,6,8-trisulfonic acidRelated Search:

COPPER(II) TRIFLUOROMETHANESULFONATE 1-Naphthylamine Lithium trifluoromethanesulfonate EPA Trifluoromethanesulfonic acid Trifluoromethanesulfonic anhydride Naphthionic acid Folic acid Sodium 4-amino-1-naphthalenesulfonate Ethyl 2-(Chlorosulfonyl)acetate Citric acid Ascoric Acid 2,4,6-TRINITROBENZENESULFONIC ACID Suramin sodium 2-NAPHTHYLAMINE-4,6,8-TRISULFONIC ACID 1-naphthylamine-3,6,8-trisulfonic acid disodium salt,1-NAPHTHYLAMINE-3,6,8-TRISULFONIC ACID DISODIUM SALT HYDRATE 2-NAPHTHYLAMINE-3,6,8-TRISULFONIC ACID (AMINO K ACID),2-NAPHTHYLAMINE-3,6,8-TRISULFONIC ACID 8-NITRO-1,3,5-NAPHTHALENETRISULFONIC ACID

1-NAPHTHYLAMINE-4,6,8-TRISULFONIC ACID

8-AMINO-1,3,5-NAPHTHALENETRISULFONIC ACID

8-AMINO-NAPHTHALENE-1,3,5-TRISULFONIC ACID

8-aminonaphthalene-1,3,5-trisulphonic acid

8-azanylnaphthalene-1,3,5-trisulfonic acid

1,3,5-Naphthalenetrisulfonic acid, 8-amino-

8-aminonaphthalene-1,3,5-trisulfonicaci

17894-99-4