ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE

Product Name: ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE
CAS No.: 107407-80-7
Chemical Name: ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE
Synonyms: Ethylpyrrol[1,2-c]pyrimidine-3-carboxylate;Ethyl pyrrolo[1,2-c]pyriMidin-3-carboxylate;ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE;ethyl pyrrolo[1,2-f]pyrimidine-3-carboxylate;Pyrrolo<1,2-c>pyrimidin-3-carbonsaeure-ethylester;3-pyrrolo[1,2-c]pyrimidinecarboxylic acid ethyl ester;Pyrrolo[1,2-c]pyrimidine-3-carboxylic acid, ethyl ester;3-[ethoxy(oxo)Methane]pyrazolo[1,2-a][1,2,4]triazin-1-yl;ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE ISO 9001：2015 REACH
CBNumber: CB2201483
Molecular Formula: C10H10N2O2
Formula Weight: 190.2
MOL File: 107407-80-7.mol

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ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE Property

Melting point:: 69-70°C
Density: 1.22±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: -0.16±0.30(Predicted)
Appearance: Light yellow to light brown Solid

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Safety

HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: Y6980
Product name: Ethylpyrrolo[1,2-c]pyrimidine-3-carboxylate
Packaging: 100mg
Price: $192
Updated: 2021/12/16

Matrix Scientific

Product number: 043285
Product name: Ethyl pyrrolo[1,2-c]pyrimidine-3-carboxylate
Purity: >95%
Packaging: 500mg
Price: $267
Updated: 2021/12/16

AK Scientific

Product number: Y6980
Product name: Ethylpyrrolo[1,2-c]pyrimidine-3-carboxylate
Packaging: 250mg
Price: $275
Updated: 2021/12/16

Apolloscientific

Product number: OR32327
Product name: Ethylpyrrolo[1,2-c]pyrimidine-3-carboxylate
Purity: 95%
Packaging: 1g
Price: $298
Updated: 2021/12/16

Matrix Scientific

Product number: 043285
Product name: Ethyl pyrrolo[1,2-c]pyrimidine-3-carboxylate
Purity: >95%
Packaging: 1g
Price: $410
Updated: 2021/12/16

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ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

1003-29-8

2999-46-4

107407-80-7

General procedure for the synthesis of ethyl pyrrolo[1,2-c]pyrimidine-3-carboxylate from 2-pyrrole carboxaldehyde and ethyl isocyanoacetate: to a solution of 1H-pyrrole-2-carboxaldehyde (9.51 g, 100.0 mmol, 1.0 eq.) in dichloromethane (DCM, 150.0 mL) was added 1,8-diazadicyclohexadec-7-ene (DBU, 15.2 g, 100.0 mmol, 1.0 eq.). 100.0 mmol, 1.0 equiv) followed by ethyl isocyanoacetate (11.3 g, 100.0 mmol, 1.0 equiv). The reaction mixture was heated to reflux and maintained for 3 hours. Upon completion of the reaction, the reaction was quenched by the addition of 10% aqueous acetic acid (250 mL) and the organic phase was separated. The organic phase was washed sequentially with water (100 mL x 2), dried over anhydrous magnesium sulfate (MgSO?), filtered and concentrated. The residue was purified by column chromatography (petroleum ether/ethyl acetate=4/1, v/v) to afford the target product ethyl pyrrolo[1,2-c]pyrimidine-3-carboxylate as a yellow solid (18.5 g, 97.3% yield).

References

[1] Patent: WO2018/35061, 2018, A1. Location in patent: Paragraph 0448
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 14, p. 4231 - 4239
[3] Patent: US2003/236264, 2003, A1. Location in patent: Page 49
[4] Tetrahedron Letters, 1996, vol. 37, # 24, p. 4263 - 4266

ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE 107407-80-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-12

107407-80-7, ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATERelated Search:

1H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 4-chloro-, ethyl ester ETHYL 4-CHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE-7-CARBOXYLATE ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate ethyl 4-hydroxy-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate 3-(1-METHYL-1H-PYRROL-2-YL)-ACRYLIC ACID ETHYL ESTER Pyrrolo[1,2-c]pyrimidine-3-carboxylic acid (9CI) ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE ethyl 6-bromoH-pyrrolo[1,2-f]pyrimidine-3-carboxylate

ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE

Ethylpyrrol[1,2-c]pyrimidine-3-carboxylate

ethyl pyrrolo[1,2-f]pyrimidine-3-carboxylate

3-[ethoxy(oxo)Methane]pyrazolo[1,2-a][1,2,4]triazin-1-yl

Ethyl pyrrolo[1,2-c]pyriMidin-3-carboxylate

3-pyrrolo[1,2-c]pyrimidinecarboxylic acid ethyl ester

Pyrrolo<1,2-c>pyrimidin-3-carbonsaeure-ethylester

Pyrrolo[1,2-c]pyrimidine-3-carboxylic acid, ethyl ester

ETHYL PYRROLO[1,2-C]PYRIMIDINE-3-CARBOXYLATE ISO 9001：2015 REACH

107407-80-7

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