ChemicalBook > CAS DataBase List > trans-3-Indoleacrylic acid

trans-3-Indoleacrylic acid

Product Name
trans-3-Indoleacrylic acid
CAS No.
29953-71-7
Chemical Name
trans-3-Indoleacrylic acid
Synonyms
INDOLE-3-ACRYLIC ACID;INDOLE ACRYLIC ACID;TRANS-INDOLE-3-ACRYLIC ACID;SKL466;trans-IAA;TIMTEC-BB SBB003692;RARECHEM BK HD 0025;Indole-3-crylic acid;Indole-3-butyic acid;Trans-3-Indoleacrylicn
CBNumber
CB2202187
Molecular Formula
C11H9NO2
Formula Weight
187.19
MOL File
29953-71-7.mol
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trans-3-Indoleacrylic acid Property

Melting point:
185 °C (dec.)(lit.)
Boiling point:
321.94°C (rough estimate)
Density 
1.1963 (rough estimate)
refractive index 
1.4900 (estimate)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
4.59±0.10(Predicted)
form 
powder
color 
white to light yellow
Water Solubility 
freely soluble
BRN 
6317
Stability:
Stable under recommended storage conditions., Stable Under Recommended Storage C
InChI
InChI=1S/C11H9NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-7,12H,(H,13,14)/b6-5+
InChIKey
PLVPPLCLBIEYEA-AATRIKPKSA-N
SMILES
C(O)(=O)/C=C/C1C2=C(NC=1)C=CC=C2
CAS DataBase Reference
29953-71-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
NL3680000
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I3807
Product name
trans-3-Indoleacrylic acid
Purity
98%
Packaging
1g
Price
$71
Updated
2025/07/31
Sigma-Aldrich
Product number
I3807
Product name
trans-3-Indoleacrylic acid
Purity
98%
Packaging
10g
Price
$178
Updated
2025/07/31
TRC
Product number
I577430
Product name
trans-Indole-3-acrylic acid
Packaging
1g
Price
$135
Updated
2021/12/16
Adipogen Life Sciences
Product number
AG-CR1-3677-G001
Product name
trans-Indole-3-acrylic acid
Purity
≥98%
Packaging
1g
Price
$60
Updated
2021/12/16
AHH
Product number
MT-15748
Product name
Indole-3-acrylicacid
Purity
98%
Packaging
25g
Price
$228
Updated
2021/12/16
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trans-3-Indoleacrylic acid Chemical Properties,Usage,Production

Chemical Properties

LIGHT BROWN CRYSTALLINE POWDER

Uses

trans-3-Indoleacrylic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals.

Application

trans-3-Indoleacrylic acid is a metabolite of tryptophan.
Chromophoric L-Trp analog used to probe the allosteric properties of the internal aldimine of tryptophan synthase. Also shown to be a moderate inhibitor of tryptophan synthase, trypothan-2,3-dioxygenase (TDO), indoleamine-2,3-dioxygenase (IDO), L-dopachrome isomerase and xanthine oxidase.
Reagent used as a matrix for MALDI-TOF mass spectroscopy in order to characterize and analyze polyphenols and synthetic polymers.

Definition

ChEBI: trans-3-Indoleacrylic acid is an alpha,beta-unsaturated monocarboxylic acid that is acrylic acid in which one of the hydrogens at position 3 is replaced by an indol-3-yl group. It is an alpha,beta-unsaturated monocarboxylic acid and a member of indoles. It derives from an acrylic acid. It is a conjugate acid of an (E)-3-(indol-3-yl)acrylate(1-).

in vivo

Trans-3-Indoleacrylic acid (50 mg/kg, i.p., three times a week) promotes tumor development in HT29 tumor-bearing xenograft nu/nu mice [1].

Animal Model:HT29 tumor-bearing xenograft nu/nu mice[1]
Dosage:50 mg/kg
Administration:Intraperitoneal injection, three times a week
Result:Promoted tumor growth with deficiency of AHR or FSP1.

IC 50

Microbial Metabolite

trans-3-Indoleacrylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from trans-3-Indoleacrylic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
trans-3-Indoleacrylic acid 29953-71-7
Price
US $0.00/g
Min. Order
1g
Purity
≥98.0%
Supply Ability
10kg/month
Release date
2021-09-28
Chemwill Asia Co.,Ltd.
Product
trans-3-Indoleacrylic acid trans-Indole-3-acrylic acid in stock Factory 29953-71-7
Price
US $1.00/KG
Min. Order
1KG
Purity
TOP 3 Factory in China
Supply Ability
Top 3 production capacity Factory
Release date
2019-04-03
Chemwill Asia Co.,Ltd.
Product
Indole-4-carboxaldehyde in stock Factory 1074-86-8
Price
US $1.00/KG
Min. Order
1KG
Purity
TOP 3 Factory in China
Supply Ability
Top 3 largest production capacity Factory
Release date
2019-04-03

29953-71-7, trans-3-Indoleacrylic acidRelated Search:

CHOLESTEROL ESTERASE FARNESENE Indole-3-acetic acid Indole-3-butyric acid 6-Benzylaminopurine Acrylic acid trans,trans-2,4-Undecadienal Indometacin TRANS-BETA-INDOLEACRYLIC ACID trans-3-Indoleacrylic acid

  • BETA-INDOLEACRYLIC ACID
  • INDOLE-3-ACRYLIC ACID
  • INDOLE ACRYLIC ACID
  • 3-BETA-INDOLEACRYLIC ACID
  • 3-(3-INDOLYL)ACRYLIC ACID
  • 2-BETA-INDOLEACRYLIC ACID
  • RARECHEM BK HD 0025
  • TIMTEC-BB SBB003692
  • TRANS-BETA-INDOLEACRYLIC ACID
  • TRANS-INDOLE-3-ACRYIC ACID
  • TRANS-INDOLE-3-ACRYLIC ACID
  • TRANS-INDOLYL-3-ACRYLIC ACID
  • TRANS-3-INDOLEACRYLIC ACID
  • Indole-3-crylic acid
  • Trans-3-Indoleacrylicn
  • trans-Indole-3-acrylic acid, 98+%
  • Indole-3-butyic acid
  • trans-3-(3-indolyl)-2-propenoic acid
  • trans 3-(3-indolyl)propenoic acid, titr 98+%
  • (E)-3-(1H-indol-3-yl)-2-propenoic acid
  • trans-3-Indoleacrylic acid trans-Indole-3-acrylic acid in stock Factory
  • (2E)-3-(1H-Indole-3-yl)acrylic acid
  • (E)-3-(1H-Indol-3-yl)acrylic acid
  • (αE)-1H-Indole-3-acrylic acid
  • trans-β-Indole acrylic acid
  • INDOLE-3-ACRYLIC ACID(IAcrA)
  • trans-3-Indoleacrylic acid,98%
  • trans-3-(1H-Indol-3-yl)prop-2-enoic acid
  • trans-3-Indoleacrylic acid 98%
  • trans-3-(1H-Indol-3-yl)acrylic acid
  • Indole-3-acrylic acid ultra pure
  • Indole-3-acrylic acid, 99.5%+
  • (E)-3-(indol-3-yl)acrylic acid
  • trans-IAA
  • 2-Propenoic acid, 3-(1H-indol-3-yl)-, (2E)-
  • rans-3-Indoleacrylicaci
  • SKL466
  • trans-3-Indoleacrylic acid, 10 mM in DMSO
  • <i>trans</i>-3-Indoleacrylic acid
  • Indole-3-acrylic acid, 98.0%+
  • 29953-71-7
  • 204-06-4
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