Inosine-5'-monophosphate Disodium Salt octahydrate

Product Name: Inosine-5'-monophosphate Disodium Salt octahydrate
CAS No.: 20813-76-7
Chemical Name: Inosine-5'-monophosphate Disodium Salt octahydrate
Synonyms: 5'-IMP,2Na;5'-IMP-Na2;5'-IMP-NA2 OCTAHYDRATE;5′-IMP,2Na octahydrate;IMP DISODIUM SALT HYDRATE;5'-INOSINIC ACID DISODIUM;methyl phosphate octahydrate;5-inosine disodium monophosphate;-INOSINIC ACID DISODIUM SALT HYDRATE;Sodium 5'-O-phosphonatoinosine hydrate
CBNumber: CB2206185
Molecular Formula: C10H16N4NaO9P
Formula Weight: 390.22
MOL File: 20813-76-7.mol

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Inosine-5'-monophosphate Disodium Salt octahydrate Property

Melting point:: 175 °C
storage temp.: Inert atmosphere,2-8°C
solubility: Aqueous Acid (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
Stability:: Hygroscopic
InChIKey: CUKXPVZZLRNKJY-UYWZPSNANA-N
SMILES: O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(NC=NC1=2)=O)O.[NaH].O |&1:1,2,3,11,r|

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Safety

Hazard Codes: Xn
Risk Statements: 62-33
Safety Statements: 36/37
WGK Germany: 2
RTECS: NM7519500
F: 1-10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18135
Product name: Inosine-5'-monophosphate (sodium salt hydrate)
Purity: ≥95%
Packaging: 5g
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 18135
Product name: Inosine-5'-monophosphate (sodium salt hydrate)
Purity: ≥95%
Packaging: 10g
Price: $48
Updated: 2024/03/01

Cayman Chemical

Product number: 18135
Product name: Inosine-5'-monophosphate (sodium salt hydrate)
Purity: ≥95%
Packaging: 25g
Price: $78
Updated: 2024/03/01

Cayman Chemical

Product number: 18135
Product name: Inosine-5'-monophosphate (sodium salt hydrate)
Purity: ≥95%
Packaging: 100g
Price: $243
Updated: 2024/03/01

TRC

Product number: I665010
Product name: Inosine-5''-monophosphateSodiumSaltHydrate
Packaging: 500mg
Price: $75
Updated: 2021/12/16

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Inosine-5'-monophosphate Disodium Salt octahydrate Chemical Properties,Usage,Production

Description

Inosine-5''-monophosphate (IMP) is a substrate of IMP dehydrogenase (IMPDH), a NAD⁺-dependent enzyme that generates xanthosine monophosphate. This is a rate-limiting step in the generation of guanosine monophosphate, which is important for DNA, RNA, and glycoprotein synthesis. Inhibitors of IMPDH, including ribavirin (Item No. 16757) and mycophenolate mofetil (Item No. 13988), have potential applications as antiviral and anti-cancer drugs. 5-Ribonucleosides, including IMP, are also involved in potentiating the umami taste sensation.

Uses

Inosine-5''-monophosphate Sodium Salt Hydrate can be used for synthesis of fresh sauce for casserole. It is a sodium salt hydrate form of Inosine 5''-monophosphate (I665003), which can be used in combination with an immune checkpoint inhibitor for cancer immunotherapy.

General Description

Inosine-5'-monophosphate Disodium Salt octahydrate is a stabilised water-soluble form of inosine-5′-monophosphate disodium (5′-IMPNa2), which contributes to the bioavailability of IMP in the human body. The substance is also used for solubility, crystal and spectral structure studies.

References

[1] WILLIAM J. WATKINS. Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH[J]. Bioorganic & Medicinal Chemistry Letters, 2006, 16 13: Pages 3479-3483. DOI: 10.1016/j.bmcl.2006.03.097
[2] GIRISH S NAIK Manoj G T. A Pharmacological Profile of Ribavirin and Monitoring of its Plasma Concentration in Chronic Hepatitis C Infection[J]. Journal of Clinical and Experimental Hepatology, 2012, 2 1: Pages 42-54. DOI: 10.1016/s0973-6883(12)60090-5
[3] KATHERINE L B BORDEN Biljana C K. Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?[J]. Leukemia & Lymphoma, 2010, 51 10: 1805-1815. DOI: 10.3109/10428194.2010.496506
[4] T. KONDOH K T. Mechanisms of Umami Taste Transduction and Umami Preference[J]. Journal of the Society of Brewing, Japan, 2001, 12 1: 829-847. DOI: 10.6013/jbrewsocjapan1988.96.829

Inosine-5'-monophosphate Disodium Salt octahydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Inosine-5'-monophosphate Disodium Salt octahydrate Suppliers

China 179 Germany 1 India 1 Japan 3 Switzerland 1 United Kingdom 1 United States 11 Global 197

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View Lastest Price from Inosine-5'-monophosphate Disodium Salt octahydrate manufacturers

WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)

Product: Inosine 5'-monophosphate disodium salt (IMP-Na2) 20813-76-7
Price: US $0.00/kg
Min. Order: 25kg
Purity: ≥98%(Excellent grade)
Supply Ability: 2tons
Release date: 2025-08-19

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5'-INOSINIC ACID DISODIUM SALT HYDRATE 20813-76-7
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-11

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Inosine 5'-monophosphate disodium salt;IMP;IMP-Na2;5'-IMP-Na2 20813-76-7
Price: US $0.00-0.00/g
Min. Order: 10000g
Purity: 99.0%min. HPLC
Supply Ability: 1000kg
Release date: 2024-11-21

20813-76-7, Inosine-5'-monophosphate Disodium Salt octahydrateRelated Search:

Inosine D-Fructose 1,6-bisphosphate trisodium salt IDP Inosine-5'-triphosphate trisodium salt Inosine-5'-monophosphate Disodium Salt octahydrate IMP 2'-Deoxyinosine-5'-diphosphate, Disodium salt Inosine-5'-diphosphoric acid disodium salt 2'-Deoxyinosine 5'-monophosphate disodium salt Guanosine 5'-monophosphate disodium salt Disodium 5'-Inosinate

Inosine-5'-monophosphate (sodium salt hydrate)

5'-Inosinic acid disodium salt octahydrate

Sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl phosphate octahydrate

INOSINE 5'-MONOPHOSPHATE DISODIUM SALT N-HYDRATE

IMP DISODIUM SALT HYDRATE

5'-IMP-NA2 OCTAHYDRATE

-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)

methyl phosphate octahydrate

5'-IMP-Na2

INOSINE-5'-MONOPHOSPHATESODIUMSALT,OCTAHYDRATE

-INOSINIC ACID DISODIUM SALT HYDRATE

5-inosine disodium monophosphate

5'-INOSINIC ACID DISODIUM SALT HYDRATE USP/EP/BP

5′-IMP,2Na octahydrate

Sodium 5'-O-phosphonatoinosine hydrate

Disodium5'-inosinateoctahydrateDisodium5'-inosinateoctahydrate

Inosine-5'-monophosphate disodium salt octahydrate

5'-inosinic acid disodium salt hydrate

inosine-5'-monophosphate disodium salt

5'-IMP,2Na

[3,4-dihydroxy-5-(6-oxo-5H-purin-9-yl)oxolan-2-yl]methyl phosphate

5'-INOSINIC ACID DISODIUM

Inosine-5'-monophosphate Disodium Salt octahydrate

5’-inosinic acid disodium salt hydrate

disodiumhydrate[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)oxolan-2-yl]methylphosphate

20813-76-7

4961-65-0

C10H11N4Na2O8P8H2O

C10H11N4O8P2NaH2O

C10H11N4O8P2Na8H2O

Nucleotides

Nucleosides, Nucleotides, Oligonucleotides

BioChemical

Biochemicals and Reagents