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AIDA

Product Name
AIDA
CAS No.
168560-79-0
Chemical Name
AIDA
Synonyms
AIDA;UPF 523;AIDA,UPF-523;UPF 523,UPF523;(R,S)-1-Aminoindane-1,5;(RS)-1-AMINOINDAN-1,5-DICARBOXYLIC ACID;(R,S)-1-Aminoindane-1,5-dicarboxylicacid;(+/-)-1-AMINOINDAN-1,5-DICARBOXYLIC ACID;(+/-)-1-AMINOINDANE-1,5-DICARBOXYLIC ACID;(±)-1-Aminoindan-1,5-dicarboxylic acid,95%
CBNumber
CB2208598
Molecular Formula
C11H11NO4
Formula Weight
221.21
MOL File
168560-79-0.mol
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AIDA Property

Boiling point:
362.26°C (rough estimate)
Density 
1.2818 (rough estimate)
refractive index 
1.5200 (estimate)
storage temp. 
0-6°C
solubility 
DMSO: 2 mg/mL
form 
solid
color 
white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
WGK Germany 
3
HS Code 
29224985
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A254
Product name
AIDA
Purity
solid
Packaging
5mg
Price
$302
Updated
2025/07/31
Sigma-Aldrich
Product number
A254
Product name
AIDA
Purity
solid
Packaging
25mg
Price
$1160
Updated
2021/12/16
Tocris
Product number
0904
Product name
AIDA
Purity
≥98%(HPLC)
Packaging
50
Price
$818
Updated
2021/12/16
Tocris
Product number
0904
Product name
AIDA
Purity
≥98%(HPLC)
Packaging
10
Price
$195
Updated
2021/12/16
Usbiological
Product number
254572
Product name
AIDA
Packaging
10mg
Price
$446
Updated
2021/12/16
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AIDA Chemical Properties,Usage,Production

Chemical Properties

white to off-white powder

Uses

AIDA is a potent and selective group I mGluR agonist.

Biological Activity

A relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu 1a ), having no effect on group II (mGlu 2 ) or group III (mGlu 4 ) receptors expressed individually in baby hamster kidney cells. Has no effect on ionotropic glutamate receptors. Centrally active following systemic administration in vivo .

in vivo

UPF-523 (0.18 mg/kg; i.p.; 0.5 ml per 100 g) results in a final concentration of 100–150 mM which is below an IC50 of 214 mM[1].

Animal Model:Naive male hooded Lister rats (320–350 g)[1]
Dosage:0.18 mg/kg
Administration:I.p.; 0.5 ml per 100 g
Result:Showed no gross motor abnormalities and normal righting reflexes.

IC 50

mGluR1a: 214 μM (IC50)

storage

Store at RT

AIDA Preparation Products And Raw materials

Raw materials

Preparation Products

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AIDA Suppliers

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168560-79-0, AIDARelated Search:

2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID 4-CARBOXYPHENYLACETIC ACID 1-Aminoindan (RS)-MCPG 1H-INDENE-1-CARBOXALDEHYDE, 2,3-DIHYDRO- INDAN-5-CARBOXALDEHYDE 2,4-dimethylphenylacetaldehyde 2-AMINO-2-PHENYLBUTYRIC ACID 2,5-DIMETHYLPHENYLACETIC ACID 4-(2-hydroxyethyl)benzoic acid (S)-(+)-1-Aminoindan (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID 1-P-TOLYL-PROPYLAMINE AIDA INDAN-5-CARBOXYLIC ACID DL-1-AMINOINDAN-1-CARBOXYLIC ACID HYDRATE AMINO-O-TOLYL-ACETIC ACID 1H-INDEN-1-AMINE, 2,3-DIHYDRO-5-METHYL-

  • 1-AMINO-2,3-DIHYDRO-1H-INDENE-1,5-DICARBOXYLIC ACID
  • (+/-)-1-AMINOINDAN-1,5-DICARBOXYLIC ACID
  • (+/-)-1-AMINOINDANE-1,5-DICARBOXYLIC ACID
  • AIDA
  • (RS)-1-AMINOINDAN-1,5-DICARBOXYLIC ACID
  • UPF 523
  • 1-AMINOINDAN-1,5-DICARBOXYLIC ACID,UPF 5 23
  • (R,S)-1-Aminoindane-1,5-dicarboxylicacid
  • AIDA,UPF-523
  • 1-Amino-2,3-dihydro-1H-indene-1,5-dicarboxylic acid, 1-Aminoindan-1, 5-dicarboxylic acid, UPF 523
  • (±)-1-Aminoindan-1,5-dicarboxylic acid,95%
  • (#1)-1-Aminoindan-1,5-dicarboxylic acidAIDA
  • (R,S)-1-Aminoindane-1,5
  • 1-Amino-2,3-dihydro-1H-indene-1,5-dicarboxylic acid1-Aminoindan-1, 5-dicarboxylic acid
  • (§1)-1-Aminoindan-1,5-dicarboxylic acid, 95%
  • (1S)-1-ammonio-2,3-dihydroindene-1,5-dicarboxylate
  • 1H-Indene-1,5-dicarboxylic acid, 1-amino-2,3-dihydro-
  • UPF 523,UPF523
  • 168560-79-0
  • Glutamate receptor