4-AMINO-2,5-DIFLUOROPHENOL

Product Name: 4-AMINO-2,5-DIFLUOROPHENOL
CAS No.: 120103-19-7
Chemical Name: 4-AMINO-2,5-DIFLUOROPHENOL
Synonyms: 4-AMINO-2,5-DIFLUOROPHENOL;Phenol,4-amino-2,5-difluoro-;2,5-Difluoro-4-hydroxyaniline;4-AMINO-2,5-DIFLUOROPHENOL ISO 9001：2015 REACH
CBNumber: CB2210575
Molecular Formula: C6H5F2NO
Formula Weight: 145.11
MOL File: 120103-19-7.mol

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4-AMINO-2,5-DIFLUOROPHENOL Property

Boiling point:: 251.8±40.0 °C(Predicted)
Density: 1.472±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
pka: 7.99±0.23(Predicted)
form: solid
color: Yellow
CAS DataBase Reference: 120103-19-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Hazard Note: Irritant
HS Code: 2908990000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A576938
Product name: 4-Amino-2,5-difluorophenol
Packaging: 1g
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA104512
Product name: 4-amino-2,5-difluorophenol
Packaging: 250mg
Price: $50
Updated: 2021/12/16

Apolloscientific

Product number: PC8310
Product name: 4-Amino-2,5-difluorophenol
Packaging: 1g
Price: $58
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4656-3-25
Product name: 4-Amino-2,5-difluorophenol
Packaging: 1g
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA104512
Product name: 4-amino-2,5-difluorophenol
Packaging: 500mg
Price: $85
Updated: 2021/12/16

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4-AMINO-2,5-DIFLUOROPHENOL Chemical Properties,Usage,Production

Uses

4-Amino-2,5-difluorophenol?is used in preparation of Phenoxypyridylpyrimidine derivatives for use as Inositol requiring enzyme 1 activity modulators.

Synthesis

868736-12-3

120103-19-7

1-(Benzyloxy)-2,5-difluoro-4-nitrobenzene (9.21 g) was dissolved in methanol (300 ml) and 10% palladium-carbon catalyst (921 mg) was added. The reaction was stirred at room temperature for 24 hours and 20 minutes under hydrogen atmosphere. Upon completion of the reaction, the atmosphere in the reaction vessel was replaced with nitrogen to terminate the reaction and the catalyst was removed by filtration through diatomaceous earth. The filtrate was concentrated under reduced pressure to afford the title compound 4-amino-2,5-difluorophenol as a brown solid (4.96 g, 99% yield). The product was characterized by 1H-NMR (DMSO-d6): δ 4.67 (1H, s), 6.53-6.64 (1H, m), 9.03 (1H, s).

References

[1] Patent: US2008/214815, 2008, A1. Location in patent: Page/Page column 18
[2] Patent: EP2119706, 2009, A1. Location in patent: Page/Page column 45
[3] Patent: EP1889836, 2008, A1. Location in patent: Page/Page column 82
[4] Patent: WO2013/180949, 2013, A1. Location in patent: Paragraph 0183
[5] Patent: WO2014/22116, 2014, A2. Location in patent: Paragraph 0181

4-AMINO-2,5-DIFLUOROPHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

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4-AMINO-2,5-DIFLUOROPHENOL Suppliers

China 53 India 1 United Kingdom 8 United States 11 Global 73

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View Lastest Price from 4-AMINO-2,5-DIFLUOROPHENOL manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 4-Amino-2,5-difluorophenol 120103-19-7
Price: US $1.10-9.90/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 100kg
Release date: 2025-08-18

Career Henan Chemical Co

Product: 4-AMINO-2,5-DIFLUOROPHENOL 120103-19-7
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-02-04

120103-19-7, 4-AMINO-2,5-DIFLUOROPHENOLRelated Search:

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4-AMINO-2,5-DIFLUOROPHENOL

2,5-Difluoro-4-hydroxyaniline

Phenol,4-amino-2,5-difluoro-

4-AMINO-2,5-DIFLUOROPHENOL ISO 9001：2015 REACH

120103-19-7

C6H5F2NO

pharmacetical

Phenol&Thiophenol&Mercaptan