Maxacalcitol
- Product Name
- Maxacalcitol
- CAS No.
- 103909-75-7
- Chemical Name
- Maxacalcitol
- Synonyms
- MAXACALCITOL;Macalciferol;Oxacalcitriol;Maxacalcitol (22-Oxacalcitriol);22-Oxa-1α,25-dihydroxycholecalciferol;(5Z,7E)-9,10-Seco-22-oxacholesta-5,7,10(19)-triene-1α,3β,25-triol;(+)-(5Z,7E)-(1S,3R,20S)-20-(3-Hydroxy-3-methylbutyloxy)-9,10-secopregna-5,7,10(19)-triene-1,3-diol;4-methylene-5Z-[2E-[(3aS)-octahydro-1S-[1S-(3-hydroxy-3-methylbutoxy)ethyl]-7aS-methyl-4H-inden-4-ylidene]ethylidene]-1R,3S-cyclohexanediol;(1R,3S,Z)-5-(2-((1S,3aS,7aS,E)-1-((S)-1-(3-hydroxy-3-methylbutoxy)ethyl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol;(1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
- CBNumber
- CB22130916
- Molecular Formula
- C26H42O4
- Formula Weight
- 418.61
- MOL File
- 103909-75-7.mol
Maxacalcitol Property
- Melting point:
- 122°
- alpha
- D20 +49.4° (c = l.00 in ethanol)
- Boiling point:
- 581.4±50.0 °C(Predicted)
- Density
- 1.09±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Soluble in DMSO
- form
- crystalline solid
- pka
- 14.43±0.40(Predicted)
- color
- White to off-white
- InChIKey
- DTXXSJZBSTYZKE-ZDQKKZTESA-N
- SMILES
- [C@@H]1(O)C/C(=C/C=C2\CCC[C@@]3(C)[C@@]\2([H])CC[C@@H]3[C@@H](OCCC(O)(C)C)C)/C(=C)[C@@H](O)C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P281Use personal protective equipment as required.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 10794
- Product name
- 22-Oxacalcitriol
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 10794
- Product name
- 22-Oxacalcitriol
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $122
- Updated
- 2024/03/01
- Product number
- 10794
- Product name
- 22-Oxacalcitriol
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $442
- Updated
- 2024/03/01
- Product number
- O752350
- Product name
- 22-Oxacalcitriol
- Packaging
- 5mg
- Price
- $435
- Updated
- 2021/12/16
- Product number
- CS-0392
- Product name
- Maxacalcitol
- Purity
- 99.71%
- Packaging
- 25mg
- Price
- $1620
- Updated
- 2021/12/16
Maxacalcitol Chemical Properties,Usage,Production
Description
Maxacalcitol is the third synthetic vitamin D analog, after paricalcitol and doxercalciferol, to be marketed for the treatment of secondary hyperparathyroidism (SHPT) associated with chronic renal failure. It is a new vitamin D3 derivative with an oxygen atom in 22-position as main structural feature (22-oxacalcitriol, OCT). This vitamin D receptor agonist has a strong inhibitory effect on synthesis and secretion of parathyroid hormone in the setting of severe parathyroid hyperplasia. Maxacalcitol induced only minor effects on calcium and phosphate metabolism unlike an agent such as 1, 25(OH)2D3 that produced hypercalcemia and hyperphosphatemia. Maxacalcitol is.
Originator
Chugai (Japan)
Uses
22-Oxacalcitriol is the noncalcemic analogue of vitamine D and was found to suppress parathyroid hormone synthesis and secretion.
Definition
ChEBI: Maxacalcitol is an organic molecular entity.
brand name
Prezios (Chugai Pharmaceutical Co., Ltd., Japan);Prezios, Oxarol.
Maxacalcitol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Maxacalcitol manufacturers
- Product
- Maxacalcitol 103909-75-7
- Price
- US $30.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2021-06-10
- Product
- Maxacalcitol 103909-75-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Maxacalcitol 103909-75-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08