Maxacalcitol

Product Name: Maxacalcitol
CAS No.: 103909-75-7
Chemical Name: Maxacalcitol
Synonyms: MAXACALCITOL;Macalciferol;Oxacalcitriol;Maxacalcitol (22-Oxacalcitriol);22-Oxa-1α,25-dihydroxycholecalciferol;(5Z,7E)-9,10-Seco-22-oxacholesta-5,7,10(19)-triene-1α,3β,25-triol;(+)-(5Z,7E)-(1S,3R,20S)-20-(3-Hydroxy-3-methylbutyloxy)-9,10-secopregna-5,7,10(19)-triene-1,3-diol;4-methylene-5Z-[2E-[(3aS)-octahydro-1S-[1S-(3-hydroxy-3-methylbutoxy)ethyl]-7aS-methyl-4H-inden-4-ylidene]ethylidene]-1R,3S-cyclohexanediol;(1R,3S,Z)-5-(2-((1S,3aS,7aS,E)-1-((S)-1-(3-hydroxy-3-methylbutoxy)ethyl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol;(1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
CBNumber: CB22130916
Molecular Formula: C26H42O4
Formula Weight: 418.61
MOL File: 103909-75-7.mol

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Maxacalcitol Property

Melting point:: 122°
alpha: D20 +49.4° (c = l.00 in ethanol)
Boiling point:: 581.4±50.0 °C(Predicted)
Density: 1.09±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Soluble in DMSO
form: crystalline solid
pka: 14.43±0.40(Predicted)
InChIKey: DTXXSJZBSTYZKE-ZDQKKZTESA-N
SMILES: [C@@H]1(O)C/C(=C/C=C2\CCC[C@@]3(C)[C@@]\2([H])CC[C@@H]3[C@@H](OCCC(O)(C)C)C)/C(=C)[C@@H](O)C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P281Use personal protective equipment as required.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10794
Product name: 22-Oxacalcitriol
Purity: ≥95%
Packaging: 500μg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 10794
Product name: 22-Oxacalcitriol
Purity: ≥95%
Packaging: 1mg
Price: $122
Updated: 2024/03/01

Cayman Chemical

Product number: 10794
Product name: 22-Oxacalcitriol
Purity: ≥95%
Packaging: 5mg
Price: $442
Updated: 2024/03/01

TRC

Product number: O752350
Product name: 22-Oxacalcitriol
Packaging: 5mg
Price: $435
Updated: 2021/12/16

ChemScene

Product number: CS-0392
Product name: Maxacalcitol
Purity: 99.71%
Packaging: 25mg
Price: $1620
Updated: 2021/12/16

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Maxacalcitol Chemical Properties,Usage,Production

Description

Maxacalcitol is the third synthetic vitamin D analog, after paricalcitol and doxercalciferol, to be marketed for the treatment of secondary hyperparathyroidism (SHPT) associated with chronic renal failure. It is a new vitamin D3 derivative with an oxygen atom in 22-position as main structural feature (22-oxacalcitriol, OCT). This vitamin D receptor agonist has a strong inhibitory effect on synthesis and secretion of parathyroid hormone in the setting of severe parathyroid hyperplasia. Maxacalcitol induced only minor effects on calcium and phosphate metabolism unlike an agent such as 1, 25(OH)2D3 that produced hypercalcemia and hyperphosphatemia. Maxacalcitol is.

Originator

Chugai (Japan)

Uses

22-Oxacalcitriol is the noncalcemic analogue of vitamine D and was found to suppress parathyroid hormone synthesis and secretion.

Definition

ChEBI: Maxacalcitol is an organic molecular entity.

brand name

Prezios (Chugai Pharmaceutical Co., Ltd., Japan);Prezios, Oxarol.

Maxacalcitol Preparation Products And Raw materials

Raw materials

Preparation Products

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Maxacalcitol Suppliers

Canada 1 China 126 India 3 United Kingdom 1 United States 12 Global 143

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View Lastest Price from Maxacalcitol manufacturers

Shanghai CRM New Material Technology Co., LTD

Product: Maxacalcitol 103909-75-7
Price: US $30.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20tons
Release date: 2021-06-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Maxacalcitol 103909-75-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Maxacalcitol 103909-75-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

103909-75-7, MaxacalcitolRelated Search:

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MAXACALCITOL

(1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

(5Z,7E)-9,10-Seco-22-oxacholesta-5,7,10(19)-triene-1α,3β,25-triol

22-Oxa-1α,25-dihydroxycholecalciferol

Oxacalcitriol

(+)-(5Z,7E)-(1S,3R,20S)-20-(3-Hydroxy-3-methylbutyloxy)-9,10-secopregna-5,7,10(19)-triene-1,3-diol

1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-

(1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol

(1R,3S,Z)-5-(2-((1S,3aS,7aS,E)-1-((S)-1-(3-hydroxy-3-methylbutoxy)ethyl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol

4-methylene-5Z-[2E-[(3aS)-octahydro-1S-[1S-(3-hydroxy-3-methylbutoxy)ethyl]-7aS-methyl-4H-inden-4-ylidene]ethylidene]-1R,3S-cyclohexanediol

Maxacalcitol (22-Oxacalcitriol)

(1R,3S,Z)-5-((E)-2-((1S,3aS,7aS)-1-((S)-1-(3-Hydroxy-3-methylbutoxy)ethyl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol

Macalciferol

103909-75-7

909-75-7

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