4'-Hydroxyphenyl Carvedilol

Product Name: 4'-Hydroxyphenyl Carvedilol
CAS No.: 142227-49-4
Chemical Name: 4'-Hydroxyphenyl Carvedilol
Synonyms: (R)-BM 14686;(S)-BM 14686;(S)-BM 140686;(R)-BM 140686;4-Hydroxycarvedilol;Carvedilol Impurity 12;(R)-4-Hydroxycarvedilol;(S)-4-Hydroxycarvedilol;4'-HYDROXYPHENYL CARVEDILOL;Carvedilol 4-Hydroxy Metabolite
CBNumber: CB2214210
Molecular Formula: C24H26N2O5
Formula Weight: 422.47
MOL File: 142227-49-4.mol

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4'-Hydroxyphenyl Carvedilol Property

Melting point:: 163-165°C
Boiling point:: 702.0±60.0 °C(Predicted)
Density: 1.305±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 9.94±0.20(Predicted)
color: White to Light Brown

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Safety

HS Code: 9999999999

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00928
Product name: 4′-Hydroxy carvedilol
Packaging: 1MG
Price: $70.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: SMB00928
Product name: 4′-Hydroxy carvedilol
Packaging: 5MG
Price: $282
Updated: 2024/03/01

Cayman Chemical

Product number: 27172
Product name: 4''-hydroxyphenyl Carvedilol
Packaging: 1mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 27172
Product name: 4''-hydroxyphenyl Carvedilol
Packaging: 5mg
Price: $356
Updated: 2024/03/01

TRC

Product number: H949120
Product name: 4’-HydroxyphenylCarvedilol
Packaging: 2mg
Price: $135
Updated: 2021/12/16

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4'-Hydroxyphenyl Carvedilol Chemical Properties,Usage,Production

Description

4’-hydroxyphenyl Carvedilol is a metabolite of carvedilol that is a more potent β-adrenergic receptor antagonist than carvedilol but has weaker vasodilatory activity. It is formed through oxidation primarily by the cytochrome P450 (CYP) isoform CYP2D6. 4’-hydroxyphenyl Carvedilol inhibits the formation of DPPH radicals in a cell-free assay.

Chemical Properties

Off-White Solid

Uses

A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.

Uses

4'-Hydroxyphenyl Carvedilol is an optically active metabolite of Carvedilol which is a multiple-action, neurohormonal antagonist that is used in the treatment of hypertension.

Uses

An optically active metabolite of Carvedilol (C184625), a nonselective ?-adrenergic blocker with α1-blocking activity.

Definition

ChEBI: 4'-Hydroxyphenyl Carvedilol is a member of carbazoles.

4'-Hydroxyphenyl Carvedilol Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-Hydroxyphenyl Carvedilol Suppliers

Canada 3 China 36 India 4 United States 9 Global 52

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142227-49-4, 4'-Hydroxyphenyl CarvedilolRelated Search:

SB 209995 Carvedilol Ketone Impurity Carvedilol Metoprolol tartrate Benazepril 8-Hydroxy Carvedilol Carvedilol Bisalkylpyrocatechol IMpurity 4'-HYDROXYPHENYL CARVEDILOL 5'-HYDROXYPHENYL CARVEDILOL (S)-(-)-5'-HYDROXYPHENYL-CARVEDILOL (R)-(+)-5'-HYDROXYPHENYL CARVEDILOL 4'-HYDROXYPHENYL CARVEDILOL-D5 (S)-(-)-4'-BENZYLOXYPHENYLOXY-CARVEDILOL 4'-HYDROXYPHENYLCARVEDILOL-D3 4'-BENZYLOXY-CARVEDILOL (R)-(+)-4'-BENZYLOXY-CARVEDILOL 4'-Hydroxyphenyl Carvedilol

(R)-(+)-4'-HYDROXYPHENYL-CARVEDILOL

(S)-(-)-4'-HYDROXYPHENYL-CARVEDILOL

(R)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol

(R)-4-Hydroxycarvedilol

(R)-BM 140686

(R)-BM 14686

(S)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol

(S)-4-Hydroxycarvedilol

(S)-BM 140686

(S)-BM 14686

4-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]aMino]ethoxy]-3-Methoxyphenol

Carvedilol 4-Hydroxy Metabolite

Carvedilol Impurity 12

Carvedilol metabolite 4-Hydroxyphenyl Carvedilol

4'-HYDROXYPHENYL CARVEDILOL

4-Hydroxycarvedilol

Phenol, 4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxy-

4’-Hydroxyphenyl Carvedilol (10mM in DMSO)

4-Hydroxyphenyl CarvedilolQ: What is 4-Hydroxyphenyl Carvedilol Q: What is the CAS Number of 4-Hydroxyphenyl Carvedilol Q: What is the storage condition of 4-Hydroxyphenyl Carvedilol Q: What are the applications of 4-Hydroxyphenyl Carvedilol

4-(2-((3-((9H-Carbazol-4-yl)oxy)-2-hydroxypropyl)amino)ethoxy)-3-methoxyphenol (Carvedilol Impurity)

142227-49-4

C24H26N2O5

Metabolite

Aromatics

Heterocycles

Chiral Reagents

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals