4'-Hydroxyphenyl Carvedilol
- Product Name
- 4'-Hydroxyphenyl Carvedilol
- CAS No.
- 142227-49-4
- Chemical Name
- 4'-Hydroxyphenyl Carvedilol
- Synonyms
- (R)-BM 14686;(S)-BM 14686;(S)-BM 140686;(R)-BM 140686;4-Hydroxycarvedilol;Carvedilol Impurity 12;(R)-4-Hydroxycarvedilol;(S)-4-Hydroxycarvedilol;4'-HYDROXYPHENYL CARVEDILOL;Carvedilol 4-Hydroxy Metabolite
- CBNumber
- CB2214210
- Molecular Formula
- C24H26N2O5
- Formula Weight
- 422.47
- MOL File
- 142227-49-4.mol
4'-Hydroxyphenyl Carvedilol Property
- Melting point:
- 163-165°C
- Boiling point:
- 702.0±60.0 °C(Predicted)
- Density
- 1.305±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.94±0.20(Predicted)
- color
- White to Light Brown
Safety
- HS Code
- 9999999999
N-Bromosuccinimide Price
- Product number
- SMB00928
- Product name
- 4′-Hydroxy carvedilol
- Packaging
- 1MG
- Price
- $70.3
- Updated
- 2024/03/01
- Product number
- SMB00928
- Product name
- 4′-Hydroxy carvedilol
- Packaging
- 5MG
- Price
- $282
- Updated
- 2024/03/01
- Product number
- 27172
- Product name
- 4''-hydroxyphenyl Carvedilol
- Packaging
- 1mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 27172
- Product name
- 4''-hydroxyphenyl Carvedilol
- Packaging
- 5mg
- Price
- $356
- Updated
- 2024/03/01
- Product number
- H949120
- Product name
- 4’-HydroxyphenylCarvedilol
- Packaging
- 2mg
- Price
- $135
- Updated
- 2021/12/16
4'-Hydroxyphenyl Carvedilol Chemical Properties,Usage,Production
Description
4’-hydroxyphenyl Carvedilol is a metabolite of carvedilol that is a more potent β-adrenergic receptor antagonist than carvedilol but has weaker vasodilatory activity. It is formed through oxidation primarily by the cytochrome P450 (CYP) isoform CYP2D6. 4’-hydroxyphenyl Carvedilol inhibits the formation of DPPH radicals in a cell-free assay.
Chemical Properties
Off-White Solid
Uses
A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.
Uses
4'-Hydroxyphenyl Carvedilol is an optically active metabolite of Carvedilol which is a multiple-action, neurohormonal antagonist that is used in the treatment of hypertension.
Uses
An optically active metabolite of Carvedilol (C184625), a nonselective ?-adrenergic blocker with α1-blocking activity.
Definition
ChEBI: 4'-Hydroxyphenyl Carvedilol is a member of carbazoles.
4'-Hydroxyphenyl Carvedilol Preparation Products And Raw materials
Raw materials
Preparation Products
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