NPPDGF
- Product Name
- NPPDGF
- Chemical Name
- NPPDGF
- Synonyms
- PDGF;NPPDGF;PORCINE PDGF;PDGF, PORCINE PLATELETS;PLATELET-DERIVED GROWTH FACTOR PORCINE;PORCINE PLATELET-DERIVED GROWTH FACTOR;PLATELET-DERIVED GROWTH FACTOR, PORCINE PLATELETS;Platelet-Derived Growth Factor from porcine platelets;Platelet-Derived Growth Factor from human platelets
- CBNumber
- CB2218223
- Formula Weight
- 0
- MOL File
- Mol file
NPPDGF Property
- storage temp.
- -20°C
- form
- lyophilized powder
- color
- white
- biological source
- human
Safety
- WGK Germany
- 3
- Storage Class
- 11 - Combustible Solids
N-Bromosuccinimide Price
- Product number
- P8953
- Product name
- Platelet-Derived Growth Factor from porcine platelets
- Purity
- PDGF, lyophilized powder, suitable for cell culture
- Packaging
- 5μg
- Price
- $542
- Updated
- 2025/07/31
- Product number
- P8147
- Product name
- Platelet-Derived Growth Factor from human platelets
- Purity
- PDGF, lyophilized powder, suitable for cell culture
- Packaging
- 1μG
- Price
- $482
- Updated
- 2023/01/07
- Product number
- P8147
- Product name
- Platelet-Derived Growth Factor from human platelets
- Purity
- PDGF, 5 μg/vial, lyophilized powder, suitable for cell culture
- Packaging
- 5μG
- Price
- $1450
- Updated
- 2023/01/07
- Product number
- P8147
- Product name
- Platelet-Derived Growth Factor from human platelets
- Purity
- PDGF, 5 μg/vial, lyophilized powder, suitable for cell culture
- Packaging
- 1VIAL
- Price
- $449
- Updated
- 2022/05/15
- Product number
- 357957
- Product name
- PDGF
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
NPPDGF Chemical Properties,Usage,Production
Uses
PDGF is a chemoattractant for fibroblasts, smooth muscle cells, monocytes and neutrophils. Also, it acts on fibroblasts and other cells that initiate healing and tissue restoration.
General Description
Platelet-derived growth factor (PDGF) is expressed as homo and heterodimers: PDGF-AB FDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD. The PDGF gene is highly conserved and is mapped to human chromosome 7p22.3. The active form of PDGF exists as disulfide-linked dimers. It consists of cystine-knot-fold growth factor domain, which is highly conserved, except for the N-terminal prodomain, which shows variation in length among the isoforms.
Biochem/physiol Actions
Platelet-derived growth factor (PDGF), not only functions as a growth factor, but also participates in chemotaxis for triggering cell movement. Elevated levels of placental PDGF is observed during the late first and third-trimester pregnancies. PDGF is associated with wound healing. PDGFRα (PDGF receptor α ) phosphorylation, mediated by PDGFA activates pathways associated with cancer. PDGFA has been indicated to induce growth and metastasis in human hepatocellular carcinoma. Vascular endothelial growth factor expression is regulated by PDGF-AA autocrine signaling and is known to promote tumor angiogenesis in vivo. PDGF-BB isomer is found to be critical in angiogenesis and is highly expressed in tumor, mediating oncogenic pericyte recruitment. PDGF-BB is an important regulator of bone homeostasis, repair and regeneration.
NPPDGF Preparation Products And Raw materials
Raw materials
Preparation Products
NPPDGF Suppliers
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 21-20338288
- ordercn@merckgroup.com
- Country
- China
- ProdList
- 6394
- Advantage
- 58
- Tel
- 021-60514606 18321282235
- sale1@shybsw.net
- Country
- China
- ProdList
- 6310
- Advantage
- 58