ChemicalBook > CAS DataBase List > 3-METHYL-2-OXOVALERIC ACID

3-METHYL-2-OXOVALERIC ACID

Product Name: 3-METHYL-2-OXOVALERIC ACID
CAS No.: 1460-34-0
Chemical Name: 3-METHYL-2-OXOVALERIC ACID
Synonyms: 3-METHYL-2-OXOPENTANOIC ACID;2-KETO-3-METHYLVALERIC ACID;α-Keto-β-methylvaleric acid;3-METHYL-2-OXOVALERIC;METHYLETHYLPYRUVIC ACID;3-methyl-2-oxovalericaci;3-METHYL-2-OXOVALERIC ACID;2-Oxo-3-methylvaleric acid;α-Keto-3-methylvaleric acid;3-Methyl-2-oxovalericAcid>
CBNumber: CB2218546
Molecular Formula: C6H10O3
Formula Weight: 130.14
MOL File: 1460-34-0.mol

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3-METHYL-2-OXOVALERIC ACID Property

Melting point:: 42°C
Boiling point:: 84 °C / 18mmHg
Density: 1.087±0.06 g/cm3(Predicted)
FEMA: 3870 | 3-METHYL-2-OXOPENTANOIC ACID
storage temp.: Refrigerator
solubility: DMSO : 130 mg/mL (998.92 mM)
pka: 2.65±0.54(Predicted)
form: powder to crystal
color: White to Light yellow
JECFA Number: 632
InChIKey: JVQYSWDUAOAHFM-UHFFFAOYSA-N
LogP: 0.17
CAS DataBase Reference: 1460-34-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-36
Safety Statements: 26-36/37/39-36
HS Code: 2918300090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS000039
Product name: 3-Methyl-2-oxopentanoic acid
Purity: AldrichCPR
Packaging: 50MG
Price: $66.1
Updated: 2025/07/31

TCI Chemical

Product number: K0020
Product name: 3-Methyl-2-oxovaleric Acid
Purity: >95.0%(GC)(T)
Packaging: 1g
Price: $200
Updated: 2025/07/31

TCI Chemical

Product number: K0020
Product name: 3-Methyl-2-oxovaleric Acid
Purity: >95.0%(GC)(T)
Packaging: 5g
Price: $594
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: CHM0023771
Product name: 3-METHYL-2-OXOPENTANOIC ACID
Purity: 95.00%
Packaging: 5G
Price: $970.2
Updated: 2021/12/16

ChemScene

Product number: CS-0059473
Product name: 3-Methyl-2-oxovaleric Acid
Purity: 99.81%
Packaging: 100mg
Price: $80
Updated: 2021/12/16

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3-METHYL-2-OXOVALERIC ACID Chemical Properties,Usage,Production

Uses

3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone[1][2].

Definition

ChEBI: A 2-oxo monocarboxylic acid that is valeric acid carrying oxo- and methyl substituents at C-2 and C-3, respectively. An alpha-keto acid analogue and metabolite of isoleucine in man, animals and bacteria. Used as a clinical marker for maple syrup urine disease (MSUD).

Synthesis Reference(s)

The Journal of Organic Chemistry, 39, p. 600, 1974 DOI: 10.1021/jo00919a004

in vivo

In uric acid stone urinary environment, the levels of 3-Methyl-2-oxovaleric acid is elevated ^[2].

IC 50

Human Endogenous Metabolite

References

[1] Ghoochani BFNM, et, al. Metabolomics diagnostic approach to mustard airway diseases: a preliminary study. Iran J Basic Med Sci. 2018 Jan;21(1):59-69. DOI:10.22038/IJBMS.2017.23792.5982
[2] Xu S, et al. Self-control study of multi-omics in identification of microenvironment characteristics in urine of uric acid stone. Sci Rep. 2024 Oct 24;14(1):25165. DOI:10.1038/s41598-024-76054-0

3-METHYL-2-OXOVALERIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3-METHYL-2-OXOVALERIC ACID Suppliers

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1460-34-0, 3-METHYL-2-OXOVALERIC ACIDRelated Search:

3-METHYL-2-OXOVALERIC ACID (+/-)-3-METHYL-2-OXOVALERIC ACID SODIUM SALT 3-METHYL-2-OXOVALERIC ACID CALCIUM SALT fluocortin 3-METHYL-2-OXOPENTANOIC ACID CALCIUM (S)-METHYL 4-(BENZYLOXYCARBONYLAMINO)-5-(TERT-BUTYLDIMETHYLSILYLOXY)PENTANOATE 4-METHYL-2-OXOVALERIC ACID 95+%,4-METHYL-2-OXOVALERIC ACID 3-METHYL-2-OXOVALERIC ACID CALCIUM SALT 4-METHYL-2-OXOVALERIC ACID SODIUM SALT Ketoleucine calcium salt dihydrate 4-METHYL-3-OXOVALERIC ACID METHYL ESTER (S)-METHYL 4-(BOC-AMINO)-5-TBDMS-PENTANOATE Gemfibrozil VALERIC ACID ALPHA-HYDROXY-BETA-OXALOSUCCINIC ACID TRISODIUM SALT ETHYL 4-(4-CHLOROPHENYL)-3-METHYL-2,4-DIOXO-BUTYRATE ketomycin 3-METHYL-2-OXOPENTANOIC ACID, CALCIUM SALT DIHYDRATE

DL-3-METHYL-2-OXOVALERIC ACID

METHYLETHYLPYRUVIC ACID

Pentanoic acid, 3-methyl-2-oxo-

(3S)-3-methyl-2-oxo-pentanoic acid

alpha-keto-beta-methyl-valerate

2-KETO-3-METHYL-N-PENTANOIC ACID

2-KETO-3-METHYLVALERIC ACID

3-METHYL-2-OXO-N-PENTANOIC ACID

3-METHYL-2-OXOPENTANOIC ACID

3-METHYL-2-OXOVALERIC ACID

alpha-keto-beta-methylvalericacid

2-Oxo-3-methylvaleric acid

α-Keto-3-methylvaleric acid

α-Keto-β-methyl-n-valeric acid

α-Keto-β-methylvaleric acid

3-Methyl-2-oxopentanoic acid AldrichCPR

3-Methyl-2-oxovalericAcid&gt

3-METHYL-2-OXOVALERIC

3-methyl-2-oxovalericaci

3 Methyl 2 oxovaleric acid,inhibit,3Methyl2oxovaleric acid,Endogenous Metabolite,Inhibitor

(±)-3-Methyl-2-oxovaleric acid

1460-34-0

pharmacetical