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Sodium ketoisocaproate

Product Name
Sodium ketoisocaproate
CAS No.
4502-00-5
Chemical Name
Sodium ketoisocaproate
Synonyms
4-METHYL-2-OXOPENTANOIC ACID SODIUM SALT;Ketoleucine sodium;Sodium ketoisocaproat;Sodium ketoisocaproate;KETOLEUCINE SODIUM SALT;SodiuM α-oxoisocaproate;SodiuM 2-Ketoisocaproate;SODIUM ALPHA-KETOISOCAPRATE;A-ketoisocaproic acid sodium;SODIUM ALPHA-KETOISOCAPROATE
CBNumber
CB8738978
Molecular Formula
C6H9NaO3
Formula Weight
152.12
MOL File
4502-00-5.mol
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Sodium ketoisocaproate Property

Melting point:
275 °C (dec.)(lit.)
storage temp. 
2-8°C
solubility 
Water (Slightly)
form 
Solid
color 
White to Off-White
Odor
at 100.00 %. butyric valeric buttery
Odor Type
buttery
JECFA Number
633.1
BRN 
4239297
Stability:
Hygroscopic
LogP
0.17
CAS DataBase Reference
4502-00-5(CAS DataBase Reference)
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Safety

Safety Statements 
24/25-22
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
K0629
Product name
Sodium 4-methyl-2-oxovalerate
Purity
leucine metabolite
Packaging
1g
Price
$95.4
Updated
2024/03/01
Sigma-Aldrich
Product number
K0629
Product name
Sodium 4-methyl-2-oxovalerate
Purity
leucine metabolite
Packaging
5g
Price
$395
Updated
2024/03/01
Cayman Chemical
Product number
21052
Product name
4-methyl-2-Oxovalerate (sodium salt)
Purity
≥95%
Packaging
1g
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
21052
Product name
4-methyl-2-Oxovalerate (sodium salt)
Purity
≥95%
Packaging
5g
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
21052
Product name
4-methyl-2-Oxovalerate (sodium salt)
Purity
≥95%
Packaging
10g
Price
$283
Updated
2024/03/01
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Sodium ketoisocaproate Chemical Properties,Usage,Production

Occurrence

Reported found in banana, asparagus, cheese, white wine, cocoa, blue cheese and provolone cheese.

Uses

Sodium 4-methyl-2-oxovalerate has been used for quantifying branched-chain keto acids from cell extracts by HPLC-fluorescence method.

Uses

4-Methyl-2-oxovaleric Acid is an α-ketomonocarboxylic acid that triggers insulin release by acting upon receptor sites which differ from those occupied by amino acids. 4-Methyl-2-oxovaleric Acid is an intermediate in the metabolism of Leucine.

Biochem/physiol Actions

α-Ketoisocaproic acid is a leucine metabolite that is known to induce insulin secretion from the βcells of pancreas. Enteral infusion of aα-Ketoisocaproate is found to ameliorate, endotoxemic condition. The resulting ketone bodies obtained from its conversion, might serve as an energy source. Accumulation of α-Ketoisocaproic acid is characterized in branched chain ketoaciduria, which is caused due to the lack of branched chain L-2-keto acid dehydrogenase activity. α-Ketoisocaproic acid causes dissociation in the oxidative phosphorylation reaction and acts as a metabolic inhibitor of α-ketoglutarate dehydrogenase. Thus, leads to a defect in the mitochondrial homeostasis, observed in branched chain ketoaciduria.

Sodium ketoisocaproate Preparation Products And Raw materials

Raw materials

Preparation Products

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Sodium ketoisocaproate Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
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Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17987
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
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64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
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60
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
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57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
+8618575662672 18575662672
Fax
021 51613951
Email
mzeng@3wpharm.com
Country
China
ProdList
9747
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
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View Lastest Price from Sodium ketoisocaproate manufacturers

Career Henan Chemical Co
Product
Sodium ketoisocaproate 4502-00-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-02
Cangzhou Wanyou New Material Technology Co.,Ltd
Product
Sodium ketoisocaproate 4502-00-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
800kg
Release date
2019-08-15

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