ChemicalBook > CAS DataBase List > Sodium ketoisocaproate

Sodium ketoisocaproate

Product Name
Sodium ketoisocaproate
CAS No.
4502-00-5
Chemical Name
Sodium ketoisocaproate
Synonyms
4-METHYL-2-OXOPENTANOIC ACID SODIUM SALT;Ketoleucine sodium;Sodium ketoisocaproat;Sodium ketoisocaproate;KETOLEUCINE SODIUM SALT;SodiuM α-oxoisocaproate;SodiuM 2-Ketoisocaproate;SODIUM ALPHA-KETOISOCAPRATE;A-ketoisocaproic acid sodium;SODIUM ALPHA-KETOISOCAPROATE
CBNumber
CB8738978
Molecular Formula
C6H9NaO3
Formula Weight
152.12
MOL File
4502-00-5.mol
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Sodium ketoisocaproate Property

Melting point:
275 °C (dec.)(lit.)
storage temp. 
2-8°C
solubility 
Water (Slightly)
form 
Solid
color 
White to Off-White
Odor
at 100.00 %. butyric valeric buttery
Odor Type
buttery
JECFA Number
633.1
BRN 
4239297
Stability:
Hygroscopic
LogP
0.17
CAS DataBase Reference
4502-00-5(CAS DataBase Reference)
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Safety

Safety Statements 
24/25-22
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
K0629
Product name
Sodium 4-methyl-2-oxovalerate
Purity
leucine metabolite
Packaging
1g
Price
$95.4
Updated
2024/03/01
Sigma-Aldrich
Product number
K0629
Product name
Sodium 4-methyl-2-oxovalerate
Purity
leucine metabolite
Packaging
5g
Price
$395
Updated
2024/03/01
Cayman Chemical
Product number
21052
Product name
4-methyl-2-Oxovalerate (sodium salt)
Purity
≥95%
Packaging
1g
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
21052
Product name
4-methyl-2-Oxovalerate (sodium salt)
Purity
≥95%
Packaging
5g
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
21052
Product name
4-methyl-2-Oxovalerate (sodium salt)
Purity
≥95%
Packaging
10g
Price
$283
Updated
2024/03/01
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Sodium ketoisocaproate Chemical Properties,Usage,Production

Occurrence

Reported found in banana, asparagus, cheese, white wine, cocoa, blue cheese and provolone cheese.

Uses

Sodium 4-methyl-2-oxovalerate has been used for quantifying branched-chain keto acids from cell extracts by HPLC-fluorescence method.

Uses

4-Methyl-2-oxovaleric Acid is an α-ketomonocarboxylic acid that triggers insulin release by acting upon receptor sites which differ from those occupied by amino acids. 4-Methyl-2-oxovaleric Acid is an intermediate in the metabolism of Leucine.

Biochem/physiol Actions

α-Ketoisocaproic acid is a leucine metabolite that is known to induce insulin secretion from the βcells of pancreas. Enteral infusion of aα-Ketoisocaproate is found to ameliorate, endotoxemic condition. The resulting ketone bodies obtained from its conversion, might serve as an energy source. Accumulation of α-Ketoisocaproic acid is characterized in branched chain ketoaciduria, which is caused due to the lack of branched chain L-2-keto acid dehydrogenase activity. α-Ketoisocaproic acid causes dissociation in the oxidative phosphorylation reaction and acts as a metabolic inhibitor of α-ketoglutarate dehydrogenase. Thus, leads to a defect in the mitochondrial homeostasis, observed in branched chain ketoaciduria.

Sodium ketoisocaproate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sodium ketoisocaproate manufacturers

Career Henan Chemical Co
Product
Sodium ketoisocaproate 4502-00-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-02
Cangzhou Wanyou New Material Technology Co.,Ltd
Product
Sodium ketoisocaproate 4502-00-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
800kg
Release date
2019-08-15

4502-00-5, Sodium ketoisocaproateRelated Search:

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  • Sodium ketoisocaproate
  • SODIUM 4-METHYL-2-OXOVALERATE
  • SODIUM ALPHA-KETOISOCAPRATE
  • 2-KETOISOCAPROIC ACID SODIUM SALT
  • 2-KETOISOHEXANOIC ACID SODIUM SALT
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  • 4-METHYL-2-OXOPENTANOIC ACID SODIUM SALT
  • 4-METHYL-2-OXOVALERIC ACID SODIUM SALT
  • KETOLEUCINE SODIUM SALT
  • A-ketoisocaproic acid sodium
  • 4-METHYL-2-OXOPENTANOIC ACID, SODIUM SAL T,98%
  • SODIUM ALPHA-KETOISOCAPROATE
  • Sodium4-Methyl-2-oxopentanoate
  • 4-methyl-2-oxo-pentanoate, sodium salt
  • alpha-Ketoisocaproic Acid, Sodium Salt-isopropyl-D7
  • Pentanoic acid, 4-methyl-2-oxo-, sodium salt
  • α-Ketoisocaproic Acid, Sodium Salt-isopropyl-D7
  • α-Ketoisocaproic Acid, Sodium Salt-1-13C
  • α-Ketoisocaproic Acid, Sodium Salt-methyl-D3
  • α-Ketoisocaproic acid sodium salt, 4-Methyl-2-oxopentanoic acid sodium salt, 4-Methyl-2-oxovaleric acid sodium salt, Ketoleucine sodium salt
  • Ketoleucine sodium
  • Sodium 4-methyl-2-oxovalerate,α-Ketoisocaproic acid sodium salt, 4-Methyl-2-oxopentanoic acid sodium salt, 4-Methyl-2-oxovaleric acid sodium salt, Ketoleucine sodium salt
  • 2-Oxo-4-Methylpentanoic Acid SodiuM Salt
  • SodiuM 2-Ketoisocaproate
  • SodiuM α-oxoisocaproate
  • Sodium ketoisocaproate Sodium 4-methyl-2-oxovalerate
  • 4-Methyl-2-oxovaleric Acid Sodium Sal
  • SODIUM 4-METHYL-2-OXOVALERATE, LEUCI
  • 4-methyl-2-Oxovalerate (sodium salt)
  • Sodium Ketoisocaproate (Na-KIC)
  • Sodium ketoisocaproat
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