Chelidamic acid
- Product Name
- Chelidamic acid
- CAS No.
- 138-60-3
- Chemical Name
- Chelidamic acid
- Synonyms
- 4-HYDROXYPYRIDINE-2,6-DICARBOXYLIC ACID;4-Oxo-1,4-dihydropyridine-2,6-dicarboxylic acid;CHELIDAMIC ACID HYDRATE;4-HYDROXY-2,6-PYRIDINEDICARBOXYLIC ACID;4-Hydroxypyridine-2,6-dicarboxylic acid hydrate;4-Oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid;CheL;Nsc3983;AKOS 90653;idamic acid
- CBNumber
- CB2220457
- Molecular Formula
- C7H5NO5
- Formula Weight
- 183.12
- MOL File
- 138-60-3.mol
Chelidamic acid Property
- Melting point:
- 265-270 °C
- Boiling point:
- 428.3±45.0 °C(Predicted)
- Density
- 1.726±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- 1 M NH4OH: 50mg/mL, clear to slightly hazy
- pka
- 0.12±0.40(Predicted)
- form
- powder
- color
- brown
- biological source
- synthetic (organic)
- BRN
- 476229
- InChI
- InChI=1S/C7H5NO5/c9-3-1-4(6(10)11)8-5(2-3)7(12)13/h1-2H,(H,8,9)(H,10,11)(H,12,13)
- InChIKey
- XTLJJHGQACAZMS-UHFFFAOYSA-N
- SMILES
- C1(C(O)=O)NC(C(O)=O)=CC(=O)C=1
- CAS DataBase Reference
- 138-60-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 792748
- Product name
- Chelidamic acid
- Packaging
- 1g
- Price
- $18.01
- Updated
- 2025/07/31
- Product number
- 22490
- Product name
- Chelidamic acid hydrate
- Purity
- ≥97.0% (dried material, T), ~1?mol/mol water
- Packaging
- 25g
- Price
- $152.5
- Updated
- 2025/07/31
- Product number
- C0821
- Product name
- Chelidamic Acid Monohydrate
- Purity
- >95.0%(T)
- Packaging
- 5g
- Price
- $78
- Updated
- 2025/07/31
- Product number
- C0821
- Product name
- Chelidamic Acid Monohydrate
- Purity
- >95.0%(T)
- Packaging
- 25g
- Price
- $226
- Updated
- 2025/07/31
- Product number
- C8011
- Product name
- Chelidamic acid hydrate
- Purity
- ≥95%, powder
- Packaging
- 5g
- Price
- $315
- Updated
- 2025/07/31
Chelidamic acid Chemical Properties,Usage,Production
Chemical Properties
Light yellow powder
Uses
Chelidamic acid hydrate has been used in eluent solution as a complexing additive in high-performance chelation ion chromatography (HPCIC) for speciation of iron. It has also been used as an organic ligand for the polyoxometalate (POM)-based lanthanoid hybrid compounds.
Biochem/physiol Actions
Among the most potent of the tested "conformationally restricted glutamate analogs" as an inhibitor of glutamate decarboxylase.
Synthesis
99-32-1
138-60-3
4-Oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid was synthesized from betulinic acid using a modified literature method. The specific operation was as follows: 425 mL of 30% ammonia solution (containing NH3 41.8 g, 0.21 mol) was slowly added dropwise to the reaction system at 0 °C, and the dropwise addition process was controlled to be completed within 1 hour. After the dropwise addition, the reaction mixture was stirred continuously at room temperature for 48 hours. Upon completion of the reaction, the excess ammonia solution was removed by distillation under reduced pressure. Subsequently, the residue was mixed with 50 mL of water, activated carbon was added and decolorized by refluxing for 15 minutes. After hot filtration, the filtrate was collected and, after being cooled to room temperature, the pH was adjusted with a 37% aqueous hydrochloric acid solution to 1. At this point, a white solid precipitated from the solution, which was collected by filtration, washed several times with cold water, and finally dried under vacuum for 16 h. The target compound, 4-oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid (13), was obtained as a white solid in a yield of 42 g with 98% yield.
Advantages
Chelidamic acid (1,4-dihydro-4-oxopyridine-2,6- dicarboxylic acid, CDA) is an organic material with great potential for accepting alkaline ions. It could be used as the anode material in LIBs. The new materials offer high capacity, superior cycle retention, favourable rate capability, and interesting electrochemical behaviours[1].
References
[1] Fu-Ming Wang*. “Synthesis and Characterization of Chelidonic Acid and Chelidamic Acid as Organic Anode Materials for Energy Storage.” ACS Sustainable Chemistry & Engineering 9 36 (2021): 12286–12299.
Chelidamic acid Preparation Products And Raw materials
Raw materials
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View Lastest Price from Chelidamic acid manufacturers
- Product
- Chelidamic acid 138-60-3
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2024-12-02
- Product
- Chelidamic acid 138-60-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-13
- Product
- chelidamic acid 138-60-3
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30