ChemicalBook > CAS DataBase List > (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P

(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P

Product Name
(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P
CAS No.
77275-70-8
Chemical Name
(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P
Synonyms
substance P, Pro(2)-Phe(7)-Trp(9)-;(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P;Substance P, (D-Pro2, D-Phe7, D-Trp9);ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2;H-ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2;(D-PROLINE2,D-PHENYLALANINE7,D-TRYPTOPHAN9)SUBSTANCE P);Substance P, 2-D-proline-7-D-phenylalanine-9-D-tryptophan-
CBNumber
CB2224602
Molecular Formula
C72H105N19O13S
Formula Weight
1476.79
MOL File
77275-70-8.mol
More
Less

(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Property

Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
−20°C
form 
Solid
pka
13.27±0.46(Predicted)
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Usbiological
Product number
S8000-14K
Product name
Substance P [D-Pro2, D-Phe7, D-Trp9]
Packaging
1mg
Price
$531
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0000194
Product name
[D-PRO2,D-PHE7,D-TRP9]-SUBSTANCE P
Purity
95.00%
Packaging
1MG
Price
$747.66
Updated
2021/12/16
More
Less

(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Chemical Properties,Usage,Production

Uses

[D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P (HY-P0201) analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly[1][2].

in vivo

[D-Pro2,D-Phe7,D-Trp9] Substance P (1-2 mg/kg; i.v.; once) inhibits the salivary secretion which was induced by Substance P in rats. In the dosage range at 1-1.5 mg/kg slightly increases the blood pressure[2].

References

[1] Hawcock AB, et al. Agonist effects of [D-Pro2,D-Phe7,D-Trp9]substance P--evidence for different receptors. Eur J Pharmacol. 1982 May 7;80(1):135-8. DOI:10.1016/0014-2999(82)90189-3
[2] Folkers K, et al. Chemical design of antagonists of substance P. Acta Physiol Scand. 1981 Apr;111(4):505-6. DOI:10.1111/j.1748-1716.1981.tb06771.x

(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4802
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
0571-88211921
Email
sales1@gotopbio.com
Country
CHINA
ProdList
2609
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
Nanjing chengqimei Biotechnology Co., Ltd
Tel
19850819832
Email
2173594524@qq.com
Country
China
ProdList
2638
Advantage
58
More
Less

View Lastest Price from (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P manufacturers

Career Henan Chemical Co
Product
(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P 77275-70-8
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

77275-70-8, (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE PRelated Search:


  • ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2
  • (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P
  • H-ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2
  • substance P, Pro(2)-Phe(7)-Trp(9)-
  • (D-PROLINE2,D-PHENYLALANINE7,D-TRYPTOPHAN9)SUBSTANCE P)
  • Substance P, (D-Pro2, D-Phe7, D-Trp9)
  • Substance P, 2-D-proline-7-D-phenylalanine-9-D-tryptophan-
  • 77275-70-8
  • C72H105N19O13S
  • BioChemical
  • Amino Acids and Peptides
  • Antagonist
  • Biochemicals and Reagents
  • Tachykinins
  • Peptides
  • Antagonist
  • Peptides for Cell Biology
  • Tachykinins