ChemicalBook > CAS DataBase List > (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P

(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P

Product Name
(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P
CAS No.
77275-70-8
Chemical Name
(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P
Synonyms
substance P, Pro(2)-Phe(7)-Trp(9)-;(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P;Substance P, (D-Pro2, D-Phe7, D-Trp9);ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2;H-ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2;(D-PROLINE2,D-PHENYLALANINE7,D-TRYPTOPHAN9)SUBSTANCE P);Substance P, 2-D-proline-7-D-phenylalanine-9-D-tryptophan-
CBNumber
CB2224602
Molecular Formula
C72H105N19O13S
Formula Weight
1476.79
MOL File
77275-70-8.mol
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(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Property

Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
−20°C
form 
Solid
pka
13.27±0.46(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
S8000-14K
Product name
Substance P [D-Pro2, D-Phe7, D-Trp9]
Packaging
1mg
Price
$531
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0000194
Product name
[D-PRO2,D-PHE7,D-TRP9]-SUBSTANCE P
Purity
95.00%
Packaging
1MG
Price
$747.66
Updated
2021/12/16
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(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Chemical Properties,Usage,Production

Uses

[D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P (HY-P0201) analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly[1][2].

in vivo

[D-Pro2,D-Phe7,D-Trp9] Substance P (1-2 mg/kg; i.v.; once) inhibits the salivary secretion which was induced by Substance P in rats. In the dosage range at 1-1.5 mg/kg slightly increases the blood pressure[2].

References

[1] Hawcock AB, et al. Agonist effects of [D-Pro2,D-Phe7,D-Trp9]substance P--evidence for different receptors. Eur J Pharmacol. 1982 May 7;80(1):135-8. DOI:10.1016/0014-2999(82)90189-3
[2] Folkers K, et al. Chemical design of antagonists of substance P. Acta Physiol Scand. 1981 Apr;111(4):505-6. DOI:10.1111/j.1748-1716.1981.tb06771.x

(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Preparation Products And Raw materials

Raw materials

Preparation Products

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(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Suppliers

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View Lastest Price from (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P manufacturers

Career Henan Chemical Co
Product
(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P 77275-70-8
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

77275-70-8, (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE PRelated Search:

D-Prolinamide 2,2-DIMETHYL-2,3-DIHYDRO-1-BENZOFURAN-7-CARBALDEHYDE (R)-(+)-2-AMINOMETHYL-1-ETHYLPYRROLIDINE (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P (R)-PYRROLIDINE-2-CARBALDEHYDE

  • ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2
  • (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P
  • H-ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2
  • substance P, Pro(2)-Phe(7)-Trp(9)-
  • (D-PROLINE2,D-PHENYLALANINE7,D-TRYPTOPHAN9)SUBSTANCE P)
  • Substance P, (D-Pro2, D-Phe7, D-Trp9)
  • Substance P, 2-D-proline-7-D-phenylalanine-9-D-tryptophan-
  • 77275-70-8
  • C72H105N19O13S
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