THYMINE-1-ACETIC ACID

Product Name: THYMINE-1-ACETIC ACID
CAS No.: 20924-05-4
Chemical Name: THYMINE-1-ACETIC ACID
Synonyms: T Acetic acid;Thymine acetic acid;thymidyl acetic acid;THYMINE-1-ACETIC ACID;1-Thyminylacetic acid;Thymin-1-ylacetic acid;1-Carboxymethylthymine;Thymine-N1-acetic acid;Nucleobase-T Acetic acid;ThyMine-1-acetic acid 98%
CBNumber: CB2224925
Molecular Formula: C7H8N2O4
Formula Weight: 184.15
MOL File: 20924-05-4.mol

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THYMINE-1-ACETIC ACID Property

Melting point:: 272-278 °C (dec.) (lit.)
Density: 1.416
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 3.81±0.10(Predicted)
color: White
InChI: InChI=1S/C7H8N2O4/c1-4-2-9(3-5(10)11)7(13)8-6(4)12/h2H,3H2,1H3,(H,10,11)(H,8,12,13)
InChIKey: TZDMCKHDYUDRMB-UHFFFAOYSA-N
SMILES: C1(=O)N(CC(O)=O)C=C(C)C(=O)N1

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 448958
Product name: Thymine-1-acetic acid
Purity: 98%
Packaging: 5g
Price: $190
Updated: 2025/07/31

Sigma-Aldrich

Product number: 448958
Product name: Thymine-1-acetic acid
Purity: 98%
Packaging: 25g
Price: $880.65
Updated: 2025/07/31

TCI Chemical

Product number: T4102
Product name: Thymine-1-acetic Acid
Packaging: 5G
Price: $183
Updated: 2025/07/31

TCI Chemical

Product number: T4102
Product name: Thymine-1-acetic Acid
Packaging: 25G
Price: $549
Updated: 2025/07/31

TRC

Product number: M305138
Product name: (5-Methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)aceticAcid
Packaging: 500mg
Price: $75
Updated: 2021/12/16

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THYMINE-1-ACETIC ACID Chemical Properties,Usage,Production

Synthesis

79-11-8

65-71-4

20924-05-4

5-Methyluracil (10.0 g, 79.3 mmol) was suspended in distilled water (150 mL). Aqueous potassium hydroxide solution (50 mL, 3.6 M) was slowly added to the suspension. The mixture was stirred at room temperature for 10 minutes until the solution gradually became clear. Subsequently, chloroacetic acid (15.0 g, 159 mmol) was added to the clarified solution. The reaction mixture was heated to reflux and kept for 90 minutes. Upon completion of the reaction, the solution was cooled to room temperature and acidified with concentrated hydrochloric acid to pH=3. The acidified solution was placed in a refrigerator at 4°C overnight to promote the formation of white crystalline precipitate. The white crystalline precipitate was collected by filtration and dried under vacuum using phosphorus pentoxide (P2O5), resulting in 4.5 g of thymine-1-acetic acid in 31% yield.

References

[1] Chemistry - A European Journal, 2000, vol. 6, # 1, p. 62 - 72
[2] Organic and Biomolecular Chemistry, 2006, vol. 4, # 2, p. 291 - 298
[3] Bioconjugate Chemistry, 2016, vol. 27, # 10, p. 2301 - 2306
[4] European Journal of Organic Chemistry, 2013, # 22, p. 4804 - 4815
[5] Patent: CN108478807, 2018, A. Location in patent: Paragraph 0022; 0053; 0070; 0071

THYMINE-1-ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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THYMINE-1-ACETIC ACID Suppliers

China 118 India 2 Russia 1 Switzerland 2 United Kingdom 4 United States 15 Global 142

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View Lastest Price from THYMINE-1-ACETIC ACID manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: THYMINE-1-ACETIC ACID 20924-05-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-14

Career Henan Chemical Co

Product: THYMINE-1-ACETIC ACID 20924-05-4
Price: US $6.68/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-09

20924-05-4, THYMINE-1-ACETIC ACIDRelated Search:

2-Bromo-5-nitro-1,3,4-thiadiazole SILVER NITRITE CIS-3-HEXENOIC ACID 2-[5-Cyano-6-methyl-2,4-dioxo-3,4-dihydro-(2H)-pyrimidin-1-yl]acetic acid 2-[5-Cyano-2,4-dioxo-3,4-dihydro-(2H)pyrimidin-1-yl]acetic acid [5-(aminocarbonyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]acetic acid (5-METHYL-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-ACETIC ACID METHYL ESTER THYMINE-1-ACETIC ACID

THYMINE-1-ACETIC ACID

2-[5-METHYL-2,4-DIOXO-3,4-DIHYDRO-1(2H)-PYRIMIDINYL]ACETIC ACID

THYMINE-1-YL-ACETIC ACID

[5-Methyl-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl]acetic acid

Thymin-1-ylacetic acid

(5-Methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetic acid

ThyMine-1-acetic acid 98%

1-Carboxymethylthymine

1-Thyminylacetic acid

2-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1-yl)acetic acid

Thymine acetic acid

Thymine-N1-acetic acid

2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)acetic acid

2-(5-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)acetic acid

2-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)

2-(5-methyl-2,4-dioxopyrimidin-1-yl)acetic acid

Thymin-1-ylacetic acid 98%

(5-METHYL-2,4-DIOXO-3H-PYRIMIDIN-1-YL)ACETIC ACID

Thymine-1-Acetic Acid,>98%

1(2H)-Pyrimidineacetic acid, 3,4-dihydro-5-methyl-2,4-dioxo-

2-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin -1-yl)acetic acid

Nucleobase-T Acetic acid

thymidyl acetic acid

T Acetic acid

20924-05-4

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