7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
- Product Name
- 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 16600-22-9
- Chemical Name
- 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- NSC 403048;3-Carbethoxy-4-hydroxy-7-chloroquinoline;Ethyl7-chloro-4-hydroxy-3-quinolinecarboxylate;Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate;Ethyl 4-hydroxy-7-chloroquinoline-3-carboxylate;ethyl 7-chloro-4-oxo-1H-quinoline-3-carboxylate;Ethyl-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylate;4-Hydroxy-7-chloroquinoline-3-carboxylic acid ethyl ester;7-chloro-4-oxo-1H-quinoline-3-carboxylic acid methyl ester;7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
- CBNumber
- CB2234544
- Molecular Formula
- C12H10ClNO3
- Formula Weight
- 251.67
- MOL File
- 16600-22-9.mol
7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Property
- Melting point:
- 296-298℃
- Boiling point:
- 366.8±37.0 °C(Predicted)
- Density
- 1.386
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 2.18±0.50(Predicted)
Safety
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- HCH0036646
- Product name
- ETHYL 7-CHLORO-4-HYDROXY-3-QUINOLINECARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $909.56
- Updated
- 2021/12/16
- Product number
- A157673
- Product name
- Ethyl7-chloro-4-hydroxyquinoline-3-carboxylate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1031
- Updated
- 2021/12/16
- Product number
- 16600229
- Product name
- Ethyl7-chloro-4-hydroxyquinoline-3-carboxylate
- Packaging
- 5g
- Price
- $1177.66
- Updated
- 2021/12/16
- Product number
- 16600229
- Product name
- Ethyl7-chloro-4-hydroxyquinoline-3-carboxylate
- Packaging
- 10g
- Price
- $1633.66
- Updated
- 2021/12/16
- Product number
- 16600229
- Product name
- Ethyl7-chloro-4-hydroxyquinoline-3-carboxylate
- Packaging
- 25g
- Price
- $2833.56
- Updated
- 2021/12/16
7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production
Chemical Properties
Crystalline compounds. Melting point 297 ℃.
Uses
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be used as an intermediate of chloroquine.
Synthesis
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be obtained by heating and condensing m-chloroaniline and triethyl orthoformate, then condensing with diethyl malonate with the participation of boron trifluoride, and finally heating and cyclizing in paraffin oil.
7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Suppliers
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