3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE

Product Name: 3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE
CAS No.: 257292-29-8
Chemical Name: 3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE
Synonyms: KF 38789;inhibit,Inhibitor,PSGL-1,Cell adhesion,P-selectin Inhibitor,KF-38789,KF38789,Inflammation;3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE;2H-Pyran-2-one, 3-[7-(2,4-dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl-
CBNumber: CB22446286
Molecular Formula: C19H21NO5S
Formula Weight: 375.44
MOL File: 257292-29-8.mol

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3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE Property

storage temp.: Desiccate at +4°C
solubility: <37.54mg/ml in DMSO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 2748
Product name: KF38789
Purity: ≥97%(HPLC)
Packaging: 10
Price: $223
Updated: 2021/12/16

TRC

Product number: K478120
Product name: KF38789
Packaging: 1mg
Price: $105
Updated: 2021/12/16

Usbiological

Product number: 453034
Product name: KF 38789
Packaging: 1mg
Price: $382
Updated: 2021/12/16

Usbiological

Product number: 255594
Product name: KF 38789
Packaging: 10mg
Price: $466
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0001225
Product name: KF 38789
Purity: 95.00%
Packaging: 25MG
Price: $739.2
Updated: 2021/12/16

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3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE Chemical Properties,Usage,Production

Uses

KF 38789 inhibits the binding of U937 cells to immobilized P-selectin IgG chimeric protein (P-selectin-Ig) with an IC50 value of 1.97 μM.

Definition

ChEBI: 3-[7-(2,4-dimethoxyphenyl)-1,4-thiazepan-5-ylidene]-6-methylpyran-2,4-dione is a dimethoxybenzene.

Biological Activity

Selective inhibitor of P-selectin-mediated cell adhesion (IC 50 = 1.97 μ M) that displays no effects on L-selectin- and E-selectin-mediated adhesion. Blocks P-selectin-mediated binding in vitro and leukocyte accumulation in vivo .

storage

Desiccate at +4°C

3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE Suppliers

CHINA 17 United Kingdom 1 United States 5 USA 1 Global 24

3B Pharmachem (Wuhan) International Co.,Ltd.

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Shanghai Aladdin Biochemical Technology Co.,Ltd.

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RD International Technology Co., Limited

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257292-29-8, 3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONERelated Search:

2-ETHYLTHIOMETHYLPHENOL 5-(4-HYDROXYPHENYL)PENTANOIC ACID 3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE

3-[7-(2,4-DIMETHOXYPHENYL)-2,3,6,7-TETRAHYDRO-1,4-THIAZEPIN-5-YL]-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE

KF 38789

2H-Pyran-2-one, 3-[7-(2,4-dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl-

inhibit,Inhibitor,PSGL-1,Cell adhesion,P-selectin Inhibitor,KF-38789,KF38789,Inflammation

257292-29-8