ChemicalBook > CAS DataBase List > Pemetrexed disodium hemipentahydrate

Pemetrexed disodium hemipentahydrate

Product Name
Pemetrexed disodium hemipentahydrate
CAS No.
357166-30-4
Chemical Name
Pemetrexed disodium hemipentahydrate
Synonyms
Pemetrexed disodium hydrate;PeMetrexed DisodiuM heMipenta hydrate;t 2.5 Hydrate;N-[4-[2-(2-Amino-4;Pemetrexed Disodium SaL;Pemetrexed sodium hydrate;LY-231514 Disodium Hydrate;Pemetrexed disodium(2.5HO);PEMETREXED DISODIUM 5/2 hydrate;Pemetrexed disodium 2.5 hydrate
CBNumber
CB22462178
Molecular Formula
C20H24N5NaO7
Formula Weight
469.43
MOL File
357166-30-4.mol
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Pemetrexed disodium hemipentahydrate Property

Melting point:
274-276°C (dec.)
storage temp. 
Room Temperature
solubility 
DMSO, Methanol, Water
form 
Solid
color 
Off-White
InChIKey
AEZRDYKQLPDYEH-YTCXBBKHNA-N
SMILES
C(C1=CNC2NC(N)=NC(=O)C1=2)CC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[NaH].O |&1:20,r|
CAS DataBase Reference
357166-30-4(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H341Suspected of causing genetic defects

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

AK Scientific
Product number
V2356
Product name
Pemetrexeddisodiumhydrate
Packaging
5mg
Price
$49
Updated
2021/12/16
ApexBio Technology
Product number
A3707
Product name
Pemetrexeddisodiumhemipentahydrate
Packaging
100mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-1422
Product name
Pemetrexeddisodiumhemipentahydrate
Purity
99.30%
Packaging
100mg
Price
$60
Updated
2021/12/16
ApexBio Technology
Product number
A3707
Product name
Pemetrexeddisodiumhemipentahydrate
Packaging
200mg
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-1422
Product name
Pemetrexeddisodiumhemipentahydrate
Purity
99.30%
Packaging
500mg
Price
$144
Updated
2021/12/16
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Pemetrexed disodium hemipentahydrate Chemical Properties,Usage,Production

Uses

Pemetrexed Disodium Hydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Hydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.

in vivo

The group of mice treated with PC61 plus Pemetrexed demonstrates statistically longer survival than other groups. In a survival analysis, significantly better survival is observed in the group of mice treated with PC61 plus Pemetrexed compare with those treated with PC61 alone, rat IgG plus Pemetrexed, or no treatment[2].

Pemetrexed disodium hemipentahydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Pemetrexed disodium hemipentahydrate Suppliers

Canada 1 China 259 China Hong Kong 1 Denmark 1 Germany 1 India 11 Israel 1 Russia 1 South Korea 1 Spain 1 The Netherlands 2 United States 22 Global 302
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View Lastest Price from Pemetrexed disodium hemipentahydrate manufacturers

Wuhan JiyunZen Tech Co., Ltd.
Product
Pemetrexed disodium hemipentahydrate 357166-30-4
Price
US $5.00-0.50/KG
Min. Order
1KG
Purity
99% hplc
Supply Ability
500TONS
Release date
2025-05-29
Hebei Chuanghai Biotechnology Co., Ltd
Product
Pemetrexed disodium hemipentahydrate 357166-30-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-27
Sinoway Industrial co., ltd.
Product
Pemetrexed Disodium 357166-30-4
Price
US $0.00/Kg/Bag
Min. Order
2Kg/Bag
Purity
Medicine grade / 99% min
Supply Ability
20 tons
Release date
2021-07-19

357166-30-4, Pemetrexed disodium hemipentahydrateRelated Search:

Pemetrexed Disodium Heptahydrate 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid Pemetrexed Disodium Pemetrexed

  • N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate
  • PeMetrexed sodiuM hydrate (1:2:2.5)
  • Pemetrexed disodium hydrate
  • PeMetrexed DisodiuM heMipenta hydrate
  • Pemetrexed disodium 2.5 hydrate
  • PeMetrexed (disodiuM heMipenta hydrate) (1:2:2.5)
  • L-GlutaMic acid,N-[4-[2-(2-aMino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoyl]-,sodiuM salt, hydrate (2:4:5) (9CI)
  • LY-231514 Disodium Hydrate
  • N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-Glutamic acid,sodium salt,hydrate (2:4:5)
  • Pemetrexed disodium hydrate N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate
  • PEMETREXED DISODIUM 5/2 hydrate
  • Pemetrexed disodium salt 2.5 hydrate
  • 3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate
  • N-[4-[2-(2-Amino-4
  • Pemetrexed disodium hydrate 357166-30-4
  • tetrasodium,(2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate,pentahydrate
  • eMetrexed DisodiuM heMipenta hydrate
  • Pemetrexed Disodium hemipenta hydrate ＊(GMP under applying)
  • Sodium (2S)-2-({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}amino)pentanedioate hydrate (2:1:1)
  • Pemetrexed disodium 2.5 hydrate / Pemetrexed disodium
  • Pemetrexed sodium hydrate
  • Pemetrexed Disodium SaL
  • t 2.5 Hydrate
  • Pemetrexed disodium hemipentahydrate USP/EP/BP
  • TIANFUCHEM-- 357166-30-4-- N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate in stock
  • N-[4-[2-42-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate
  • (S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid, sodium salt 2.5 hydrate
  • L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt, hydrate (2:4:5)
  • N-4-2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo2,3-dpyrimidin-5-yl)ethylbenzoyl-L-glutamic acid sodium salt hydrate (2:4:5)
  • Pemetrexed disodium(2.5HO)
  • Pemetrexid disodium hemipentahydrate, 99%min
  • 357166-30-4
  • C20H23N5NaO7
  • C20H21N5Na2O7
  • 2C20H19N5Na2O65H2O
  • C20H21N5O652H2O2Na
  • C40H48N10Na4O17
  • C20H19N5Na2O652H2O
  • Inhibitors
  • Anti-cancer&immunity
  • API
  • 357166-30-4