ChemicalBook > CAS DataBase List > METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE

METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE

Product Name
METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE
CAS No.
73427-92-6
Chemical Name
METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE
Synonyms
METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE;Methyl 6-cyano-3,5-dihydro-1-hydroxy-7-methyl-5-oxo-2-indolizinecarboxylate;6-Cyano-3,5-dihydro-1-hydroxy-7-methyl-5-oxo-2-indolizinecarboxylic Acid Methyl Ester;6-Cyano-1-hydroxy-7-methyl-5-oxo-3,5-dihydro-indolizine-2-carboxylic acid methyl ester;2-Indolizinecarboxylic acid, 6-cyano-3,5-dihydro-1-hydroxy-7-methyl-5-oxo-, methyl ester
CBNumber
CB22463539
Molecular Formula
C12H10N2O4
Formula Weight
246.22
MOL File
73427-92-6.mol
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METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE Property

Boiling point:
474.2±45.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
solubility 
DMSO
pka
4.50±1.00(Predicted)
form 
Solid
color 
Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C979525
Product name
6-Cyano-3,5-dihydro-1-hydroxy-7-methyl-5-oxo-2-indolizinecarboxylicAcidMethylEster
Packaging
250mg
Price
$295
Updated
2021/12/16
Matrix Scientific
Product number
130120
Product name
6-Cyano-1-hydroxy-7-methyl-5-oxo-3,5-dihydro-indolizine-2-carboxylicacidmethylester
Purity
95%+
Packaging
5g
Price
$2900
Updated
2021/12/16
Matrix Scientific
Product number
130120
Product name
6-Cyano-1-hydroxy-7-methyl-5-oxo-3,5-dihydro-indolizine-2-carboxylicacidmethylester
Purity
95%+
Packaging
1g
Price
$950
Updated
2021/12/16
Crysdot
Product number
CD11065163
Product name
Methyl6-cyano-1-hydroxy-7-methyl-5-oxo-3,5-dihydroindolizine-2-carboxylate
Purity
97%
Packaging
5g
Price
$1140
Updated
2021/12/16
Alichem
Product number
73427926
Product name
Methyl6-cyano-1-hydroxy-7-methyl-5-oxo-3,5-dihydroindolizine-2-carboxylate
Packaging
5g
Price
$1140
Updated
2021/12/16
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METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE Chemical Properties,Usage,Production

Uses

6-Cyano-3,5-dihydro-1-hydroxy-7-methyl-5-oxo-2-indolizinecarboxylic Acid Methyl Ester is a key intermediate in the synthesis of camptothecin (C175150) analogues.

METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE Suppliers

Canada 1 China 28 United States 3 Global 32
DONGSHENG CHIRAL PHARMA
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Tianjin Being Technology Co., Ltd.
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Jiaxing Deyi Chemical Co., Ltd.
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Jinan Feiteng Pharmaceutical Technology Co., Ltd.
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73427-92-6, METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATERelated Search:

3-Acryloylamino-1-propanol solution, 50% in water 2-CYANO-N-(3-METHOXY-PROPYL)-ACETAMIDE METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE 1-PROPYL-2(1H)-PYRIDINONE 1,4,6-TRIMETHYL-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE 2-Cyano-N,N-diethylacetamide 3-Cyano-6-methyl-2(1H)-pyridinone 4,6-Dimethyl-2-hydroxypyridine 3-Cyano-4,6-dimethyl-2-hydroxypyridine N-ALLYL-2-CYANO-ACETAMIDE 2-Hydroxy-4-methylpyridine-3-carbonitrile 2-Hydroxy-3-cyanopyridine Dimethallylamine

  • METHYL 6-CYANO-1-HYDROXY-7-METHYL-5-OXO-3,5-DIHYDROINDOLIZINE-2-CARBOXYLATE
  • 6-Cyano-1-hydroxy-7-methyl-5-oxo-3,5-dihydro-indolizine-2-carboxylic acid methyl ester
  • 6-Cyano-3,5-dihydro-1-hydroxy-7-methyl-5-oxo-2-indolizinecarboxylic Acid Methyl Ester
  • 2-Indolizinecarboxylic acid, 6-cyano-3,5-dihydro-1-hydroxy-7-methyl-5-oxo-, methyl ester
  • Methyl 6-cyano-3,5-dihydro-1-hydroxy-7-methyl-5-oxo-2-indolizinecarboxylate
  • 73427-92-6