ChemicalBook > CAS DataBase List > 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide
4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide
- Product Name
- 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide
- CAS No.
- 1032229-33-6
- Chemical Name
- 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide
- Synonyms
- A939572;SCD inhibitor;A939572;A-939572;A 939572;SCD1 Inhibitor (DMSO solution);stearoyl-CoA desaturase (SCD) inhibitor;SCD1 Inhibitor, SCD1(stearoyl-CoA desaturase 1) inhibitor;SCD1 Inhibitor (DMSO solution), SCD1(stearoyl-CoA desaturase 1) inhibitor;4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide;4-(2-Chlorophenoxy)-N-(3-(methylcarbamoyl)-phenyl)piperidine-1-carboxamide (A939572)
- CBNumber
- CB22473855
- Molecular Formula
- C20H22ClN3O3
- Formula Weight
- 387.86
- MOL File
- 1032229-33-6.mol
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4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide Property
- Boiling point:
- 633.5±55.0 °C(Predicted)
- Density
- 1.302±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- insoluble in H2O; ≥17.15 mg/mL in DMSO; ≥2.5 mg/mL in EtOH with ultrasonic
- form
- solid
- pka
- 13.65±0.70(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 19123
- Product name
- A-939572
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $55
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 19123
- Product name
- A-939572
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $105
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 19123
- Product name
- A-939572
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $495
- Updated
- 2024/03/01
Tocris
- Product number
- 4845
- Product name
- A939572
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $173
- Updated
- 2021/12/16
Tocris
- Product number
- 4845
- Product name
- A939572
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $742
- Updated
- 2021/12/16
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4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide Chemical Properties,Usage,Production
Uses
4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-piperidinecarboxamide is a stearoyl-CoA desaturase 1 (SCD1) inhibitor.
Biological Activity
A 939572 is a potent stearoyl-CoA desaturase 1 (SCD1) inhibitor (IC50 = 0.4 nM). Selective for SCD1 over a range of kinases and hERG channels. Inhibits proliferation of squamous cell carcinoma FaDu cells in vitro. Also induces cell death of undifferentiated human embryonic stem cells (ESCs). Orally bioavailable.
storage
Store at +4°C
References
[1] xin z, zhao h, serby m d, et al. discovery of piperidine-aryl urea-based stearoyl-coa desaturase 1 inhibitors. bioorganic & medicinal chemistry letters, 2008, 18(15): 4298-4302.
[2] Low glycaemic diets alter lipid metabolism to influence tumour growth Authors: Lien Et al. Nature 2021;599:302.
4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide manufacturers
Career Henan Chemical Co
- Product
- 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide 1032229-33-6
- Price
- US $2.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2020-01-08