Methyl 2-methyl-indazole-5-carboxylate
- Product Name
- Methyl 2-methyl-indazole-5-carboxylate
- CAS No.
- 1092351-86-4
- Chemical Name
- Methyl 2-methyl-indazole-5-carboxylate
- Synonyms
- Methyl 2-methyl-indazole-...;Methyl 2-methyl-indazole-5-carboxylate;Methyl 2-Methyl-2H-indazol-5-carboxylate;5-(Methoxycarbonyl)-2-methyl-2H-indazole;methyl 2-methyl-2H-indazole-5-carboxylate;Methyl 2-methyl-2H-indazole-5-carboxylate 97+%;2-Methyl-2H-indazole-5-carboxylic acid methyl ester;2H-Indazole-5-carboxylic acid, 2-methyl-, methyl ester;2-Methyl-2H-indazole-5-carboxylic acid methyl ester
- CBNumber
- CB22485605
- Molecular Formula
- C10H10N2O2
- Formula Weight
- 190.2
- MOL File
- 1092351-86-4.mol
Methyl 2-methyl-indazole-5-carboxylate Property
- Boiling point:
- 338.9±15.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- solid
- pka
- 0.01±0.30(Predicted)
- Appearance
- White to light yellow Solid
Safety
- WGK Germany
- 3
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SYX00169
- Product name
- 2-Methyl-2H-indazole-5-carboxylic acid methyl ester
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $639
- Updated
- 2025/07/31
- Product number
- M312115
- Product name
- 2-Methyl-2H-indazole-5-carboxylic acid methyl ester
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 4H23-1-P3
- Product name
- Methyl 2-methyl-2H-indazole-5-carboxylate
- Purity
- 97.0%
- Packaging
- 250mg
- Price
- $71
- Updated
- 2021/12/16
- Product number
- OR30723
- Product name
- Methyl2-methyl-2H-indazole-5-carboxylate
- Purity
- 97+%
- Packaging
- 250mg
- Price
- $64
- Updated
- 2021/12/16
- Product number
- 4H23-1-P3
- Product name
- Methyl 2-methyl-2H-indazole-5-carboxylate
- Purity
- 97.0%
- Packaging
- 1g
- Price
- $173
- Updated
- 2021/12/16
Methyl 2-methyl-indazole-5-carboxylate Chemical Properties,Usage,Production
Synthesis
473416-12-5
74-88-4
1092351-82-0
1092351-86-4
1. Methyl 1H-indazole-5-carboxylate (2.5 g, 14 mmol) was dissolved in anhydrous DMF (45 mL) under nitrogen protection. 2. Potassium carbonate (K2CO3, 4.90 g, 35.5 mmol) and iodomethane (1.77 mL, 28.4 mmol) were added sequentially to the above solution. 3. The reaction mixture was stirred at room temperature for 2 hours, then warmed to 50 °C and continued stirring overnight. 4. Upon completion of the reaction, most of the DMF was removed by concentration under reduced pressure. 5. The concentrate was dissolved in ethyl acetate (EtOAc) and washed with saturated aqueous sodium chloride (NaCl). 6. The organic phase was separated, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated to give the crude product. 7. The crude product was purified using a CombiFlash Fast Chromatography System (80g silica gel column, eluent 25-45% ethyl acetate/heptane) to afford methyl 1-methyl-1H-indazole-5-carboxylate (1.07g, 40% yield) and methyl 2-methyl-2H-indazole-5-carboxylate (227mg, 8.4% yield), respectively.
References
[1] Patent: WO2009/144554, 2009, A1. Location in patent: Page/Page column 49
Methyl 2-methyl-indazole-5-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 2-methyl-indazole-5-carboxylate Suppliers
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