MK-5172

Product Name: MK-5172
CAS No.: 1206524-85-7
Chemical Name: MK-5172
Synonyms: MK-5172;EOS-61017;UNII-RU4QU6O6X6;MK-5172 intermidiate;Grazoprevir Impurity 2;Grazoprevir Intermediate 5;(33R,35S,91R,92R,5S)-5-(tert-butyl)-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxylicacid;(1aR,5S,8S,10R,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid;(1aR,5S,8R,10S,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid;(1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid
CBNumber: CB22501167
Molecular Formula: C29H38N4O7
Formula Weight: 554.63
MOL File: 1206524-85-7.mol

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MK-5172 Property

Melting point:: 180-185oC
Boiling point:: 825.0±65.0 °C(Predicted)
Density: 1.33
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Acetone (Slightly), Chloroform (Slightly), DMSO (Slightly, Sonicated), Methanol
form: Solid
pka: 3.23±0.40(Predicted)
color: White to Off-White
Stability:: Hygroscopic
InChIKey: IVROMYPOGKZNLP-FDOFPDFBSA-N
SMILES: N1C2C(=CC=C(OC)C=2)N=C2CCCCC[C@]3([H])C[C@@]3([H])OC(=O)N[C@@H](C(C)(C)C)C(=O)N3C[C@]([H])(OC=12)C[C@H]3C(O)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological

Product number: 456309
Product name: MK 5172
Packaging: 5mg
Price: $319
Updated: 2021/12/16

ChemScene

Product number: CS-M2339
Product name: 8H-7,10-Methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylicacid,5-(1,1-dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-,(1aR,5S,8S,10R,22aR)-
Purity: 96.00%
Packaging: 5g
Price: $386
Updated: 2021/12/16

Ark Pharm

Product number: AK174303
Product name: MK-5172
Purity: 98+%
Packaging: 1mg
Price: $76
Updated: 2021/12/16

ChemScene

Product number: CS-M2339
Product name: 8H-7,10-Methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylicacid,5-(1,1-dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-,(1aR,5S,8S,10R,22aR)-
Purity: 96.00%
Packaging: 1g
Price: $115
Updated: 2021/12/16

ChemScene

Product number: CS-M2339
Product name: 8H-7,10-Methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylicacid,5-(1,1-dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-,(1aR,5S,8S,10R,22aR)-
Purity: 96.00%
Packaging: 10g
Price: $646
Updated: 2021/12/16

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MK-5172 Chemical Properties,Usage,Production

Uses

MK-5172 is a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants.

Advantages

MK-5172 has a higher barrier to resistance than first-generation protease inhibitors and is active against most variants associated with resistance to first-generation protease inhibitors. Tolerability and safety profile are good.

MK-5172 Preparation Products And Raw materials

Raw materials

Preparation Products

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MK-5172 Suppliers

China 97 India 1 Japan 1 United States 5 Global 104

Shanghai Neff Biotechnology Co., LTD

Tel: 14782051321 14782051321
Email: market@lifebiology.cn
Country: China
ProdList: 162
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

ZHIWE CHEMTECH CO LTD

Tel: 021-20221225 13917446399
Fax: QQ:115820162
Email: zwchem@163.com
Country: China
ProdList: 614
Advantage: 61

Synches Co., Ltd.

Tel: 021-53292253
Fax: 021-53292253
Email: biz@synches.com
Country: China
ProdList: 199
Advantage: 64

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

ShangHai Onsyn-Chemical Technology Co., Ltd.

Tel: 021-58359326 15900795984
Fax: +86-21-58359326
Email: angsihuaxue@126.com
Country: China
ProdList: 252
Advantage: 55

shanghai cooperpharm co.,LTD .

Tel: +86-021-58975553
Fax: +86-021-58975554
Email: sales@cooperpharm.com
Country: China
ProdList: 1210
Advantage: 56

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

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View Lastest Price from MK-5172 manufacturers

Career Henan Chemical Co

Product: MK-5172 1206524-85-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-09

1206524-85-7, MK-5172Related Search:

(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT Omarigliptin (MK-3102) Imiquimod Ribonucleic acid MK-8998 MK-1775 SCH900776 MK-0752 MK-2206 2HCl MK-4101 mk-1064 MK 0557 Mk-2461 .

MK-5172

(1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid

8H-7,10-Methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid, 5-(1,1-diMethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-Methoxy-3,6-dioxo-,(1aR,5S,8S,10R,22aR)-

(1aR,5S,8R,10S,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid

Grazoprevir Intermediate 5

(33R,35S,91R,92R,5S)-5-(tert-butyl)-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxylicacid

(1aR,5S,8S,10R,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid

MK-5172 intermidiate

EOS-61017

UNII-RU4QU6O6X6

Grazoprevir Impurity 2

1206524-85-7

C29H38N4O7

intermediates

MK-5172 intermediate