5-Chloro-4-(trifluoromethyl)pyridin-2-amine

Product Name: 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
CAS No.: 1095823-39-4
Chemical Name: 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
Synonyms: 5-Chloro-4-(trifluoromethyl);5-Chloro-4-(trifluoromethyl)pyridin-2-amine;5-Chloro-4-(trifluoromethyl)-2-pyridinamine;5-chloro-4-(trifluoromethyl)pyridin-3-amine;5-Chloro-4-trifluoromethyl-pyridin-2-ylamine;2-PyridinaMine, 5-chloro-4-(trifluoroMethyl)-;2- amino -4- three fluoromethyl -5- chlorpyridine
CBNumber: CB22504805
Molecular Formula: C6H4ClF3N2
Formula Weight: 196.56
MOL File: 1095823-39-4.mol

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5-Chloro-4-(trifluoromethyl)pyridin-2-amine Property

Boiling point:: 258.3±40.0 °C(Predicted)
Density: 1.507±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: powder
pka: 2.47±0.24(Predicted)
color: Yellow

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TRC

Product number: C597268
Product name: 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
Packaging: 500mg
Price: $310
Updated: 2021/12/16

Apolloscientific

Product number: PC01524
Product name: 2-Amino-5-chloro-4-(trifluoromethyl)pyridine
Packaging: 250mg
Price: $26
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-7-80
Product name: 2-Amino-5-chloro-4-(trifluoromethyl)pyridine
Packaging: 250mg
Price: $42
Updated: 2021/12/16

Apolloscientific

Product number: PC01524
Product name: 2-Amino-5-chloro-4-(trifluoromethyl)pyridine
Packaging: 1g
Price: $80
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-7-80
Product name: 2-Amino-5-chloro-4-(trifluoromethyl)pyridine
Packaging: 1g
Price: $128
Updated: 2021/12/16

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5-Chloro-4-(trifluoromethyl)pyridin-2-amine Chemical Properties,Usage,Production

Synthesis

106447-97-6

1095823-39-4

Synthesis of Compound A.6: To a solution of 2-amino-4-trifluoromethylpyridine (2.00 g, 12.3 mmol) in N,N-dimethylformamide (DMF, 4 mL) was slowly added a solution of 1,3-dichloro-5,5-dimethylglycolide (1.4 g, 7.4 mmol) in DMF (4 mL). The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the mixture was diluted with ether (80 mL) and washed with deionized water (10 mL). The organic phase was separated, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by fast column chromatography (eluent: 0-20% ethyl acetate/hexane) to afford compound A.6 as a light yellow oil in 65% yield.1H NMR (DMSO-d6) δ: 8.16 (s, 1H), 6.87 (s, 1H), 6.76 (br s, 1H); MS: m/z 197 [M + H]+.

References

[1] Patent: US2009/5359, 2009, A1. Location in patent: Page/Page column 33
[2] Patent: US2009/36419, 2009, A1. Location in patent: Page/Page column 78
[3] Patent: WO2010/78408, 2010, A1. Location in patent: Page/Page column 86; 87; 88

5-Chloro-4-(trifluoromethyl)pyridin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chloro-4-(trifluoromethyl)pyridin-2-amine Suppliers

China 85 India 1 United Kingdom 1 United States 5 Global 92

Jinan Kabotang Biological Technology Co.,Ltd.

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View Lastest Price from 5-Chloro-4-(trifluoromethyl)pyridin-2-amine manufacturers

Honest Joy Holdings Limited

Product: 5-Chloro-4-(trifluoromethyl)pyridin-2-amine 1095823-39-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 100 tons
Release date: 2022-01-14

Career Henan Chemical Co

Product: 5-Chloro-4-(trifluoromethyl)pyridin-2-amine 1095823-39-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-25

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1095823-39-4