ChemicalBook > CAS DataBase List > 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE

5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE

Product Name: 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE
CAS No.: 399-00-8
Chemical Name: 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE
Synonyms: 5-Bromo-4-fluorosalicylaldehyde;4-Fluoro-5-bromo-2-hydroxybenzaldehyde;5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE;Benzaldehyde, 5-bromo-4-fluoro-2-hydroxy-;5-Bromo-4-fluoro-2-hydroxybenzaldehyde 98%
CBNumber: CB2250799
Molecular Formula: C7H4BrFO2
Formula Weight: 219.01
MOL File: Mol file

Less

5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE Property

Melting point:: 81 °C
Boiling point:: 256.6±35.0 °C(Predicted)
Density: 1.826±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 6.62±0.23(Predicted)
Appearance: Light yellow to pink Solid

Less

Safety

HS Code: 2913000090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

TRC

Product number: B678313
Product name: 5-Bromo-4-fluoro-2-hydroxybenzaldehyde
Packaging: 500mg
Price: $130
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2615-B-29
Product name: 5-Bromo-4-fluoro-2-hydroxybenzaldehyde
Packaging: 1g
Price: $128
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0366994
Product name: 5-BROMO-4-FLUORO-2-HYDROXYBENZALDEHYDE
Purity: 95.00%
Packaging: 1G
Price: $223.65
Updated: 2021/12/16

AK Scientific

Product number: 5262AB
Product name: 5-Bromo-4-fluoro-2-hydroxybenzaldehyde
Packaging: 5g
Price: $316
Updated: 2021/12/16

BroadPharm

Product number: BP-11735
Product name: 5-bromo-4-fluoro-2-hydroxybenzaldehyde
Packaging: 500mg
Price: $375
Updated: 2021/12/16

Less

5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE Chemical Properties,Usage,Production

Synthesis

348-28-7

399-00-8

The general procedure for the synthesis of 5-bromo-4-fluoro-2-hydroxybenzaldehyde using 4-fluoro-2-hydroxybenzaldehyde as starting material was as follows: a solution of bromine (14.1 g, 88.3 mmol) dissolved in chloroform (25 mL) was added slowly and dropwise over a period of 10 min to a solution of chloroform (68 mL) containing 4-fluoro-2-hydroxybenzaldehyde (13.6 g, 97.1 mmol) in a round bottomed flask. The reaction mixture was stirred at room temperature for 16 hours and then the same amount of bromine (14.1 g) was added. Stirring was continued at room temperature for 24 hours. Upon completion of the reaction, the mixture was washed twice with 30% aqueous sodium thiosulfate to remove the color, followed by washing with water and drying the organic layer with anhydrous sodium sulfate. Finally, the organic phase was concentrated by decompression to afford the target product 5-bromo-4-fluoro-2-hydroxybenzaldehyde (21.3 g, 100% yield).

References

[1] Patent: WO2012/40641, 2012, A2. Location in patent: Page/Page column 135; 136
[2] Journal of Medicinal Chemistry, 2004, vol. 47, # 12, p. 3163 - 3179
[3] Patent: US6642222, 2003, B2
[4] Patent: US6593335, 2003, B1
[5] Patent: WO2013/91096, 2013, A1. Location in patent: Page/Page column 37

5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE Suppliers

China 61 Germany 1 India 1 United Kingdom 3 United States 4 Global 70

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Beijing Eternalchem Co,. Ltd.

Tel: 010-59484199 18611897322
Email: sales@eternalchem.com
Country: China
ProdList: 4383
Advantage: 60

PSN Pharmaceutical Technology Co., Ltd.

Tel: 86-25-57062118
Fax: 86-25-57065896
Email: sales@jspsn.com
Country: China
ProdList: 496
Advantage: 57

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Xinyanhe Pharmatech Co.,Ltd

Tel: 0519-85252752 15366845260
Fax: 86-0519-85683352
Email: taihuaren@vip.163.com
Country: China
ProdList: 1132
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Xi'an NewProChem Co.,Ltd.

Tel: 15332490153
Fax: QQ 2725398181
Email: newprochem@126.com
Country: China
ProdList: 991
Advantage: 55

Changzhou Anxuan Chemical, Co., Ltd.

Tel: 13912302692 13912302692;
Fax: 0519-88064678
Email: sales@anxuanchem.com
Country: China
ProdList: 4828
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai CR Corporation Limited

Tel: 13062833949; 4006653949 4006653949
Fax: QQ: 2136646215
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 9757
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Bejing Famous Pharmaceutical Technology Co., Ltd.

Tel: 13331045123
Fax: 86-10-80339217
Email: 2559355526@qq.com
Country: China
ProdList: 14193
Advantage: 58

Nanjing Chemedicine BioTech Co., Ltd.

Tel: 15722927296
Fax: -
Email: 71139532@qq.com
Country: China
ProdList: 426
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 10267
Advantage: 58

Chengdu Feibai Pharmaceutical Co., Ltd.

Tel: 028-84641798 18782128315
Email: 3302391190@qq.com
Country: China
ProdList: 9799
Advantage: 55

Allfluoro pharmaceutical co. ltd.

Tel: +86-400-0216110 +86-15958047586
Fax: 0086-21-33275002
Email: sales@allfluoro.com
Country: China
ProdList: 11385
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Zhejiang Lianshuo Biotechnology Co., Ltd.

Tel: 18616526224
Email: lianshuo@vip.126.com
Country: China
ProdList: 9607
Advantage: 58

Hebei Chuanghai Biotechnology Co., Ltd

Tel: +8615350571055
Fax: whatapp+8619930503282
Email: Sibel@chuanghaibio.com
Country: China
ProdList: 8768
Advantage: 58

Shanghai Hongshun Biological Technology Co., Ltd.

Tel: 15901914505 15901914505;
Fax: 021-54389085
Email: 3187892335@qq.com
Country: China
ProdList: 9889
Advantage: 58

Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9947
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Established by Hangzhou Boman Biochem Tech Co., Ltd

Tel: 13588048971
Email: sales@bomanbiochem.com
Country: China
ProdList: 476
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Shanghai Zhixia Chemical Technology Co., LTD

Tel: 15216847143 18321145570
Email: 1458509898@qq.com
Country: China
ProdList: 499
Advantage: 58

Jiaxing Zhejia Biotechnology Co., LTD

Tel: 0573-85609002 18367600069;
Email: zhejia01@163.com
Country: China
ProdList: 8886
Advantage: 58

Zhengzhou Hong Sheng Pharmaceutical Technology Co. Ltd.

Tel: 0371-55695890 15637198702
Email: 1677336983@qq.com
Country: China
ProdList: 13191
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 029-029-81123119 17391733320
Email: 1021@dideu.com
Country: China
ProdList: 9995
Advantage: 58

Anhui Henuo Biotechnology Co., Ltd

Tel: 18455579438
Country: China
ProdList: 16684
Advantage: 58

Shanghai Jieshikai Biotechnology Co. , Ltd.

Tel: 021-57520305 13795461237
Email: zhuruyan@jskchem.com
Country: China
ProdList: 49234
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 15697567703
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 49999
Advantage: 58

Hangzhou Bingochem Co., Ltd.

Tel: 0571-8512-5372
Email: sales@bingochem.com
Country: China
ProdList: 21669
Advantage: 58

Hubei Shanlexing Biotechnology Co., Ltd

Tel: 15972496547
Email: 15972496547@163.com
Country: China
ProdList: 2087
Advantage: 58

Hubei wei shi reagent group ltd., company

Tel: 027-59101766 13125137661
Email: 2853877621@qq.com
Country: China
ProdList: 7976
Advantage: 58

Shanghai Hansi Chemical Industry Co., Ltd.

Tel: 17717618050
Email: zllg@gh-reagent.com
Country: China
ProdList: 10420
Advantage: 58

Shanghai Ken chemical Technology Co.,ltd

Tel: 02152215958
Email: 47697177@qq.com
Country: China
ProdList: 10011
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 14580
Advantage: 58

Shanghai Amole Biotechnology Co., Ltd.

Tel: 18916360931 18916360931
Email: 2596183085@qq.com
Country: China
ProdList: 9309
Advantage: 58

SHANGHAI KEAN TECHNOLOGY CO., LTD.

Tel: +8613817748580
Fax: 021-50175322
Email: cooperation@kean-chem.com
Country: China
ProdList: 40066
Advantage: 58

Shanghai Acmec Biochemical Technology Co., Ltd.

Tel: +86-18621343501; +undefined18621343501
Email: product@acmec-e.com
Country: China
ProdList: 33338
Advantage: 58

Henan Bao Enluo International TradeCo.，LTD

Tel: +86-17331933971
Fax: deasea125996@gmail.com
Email: deasea125996@gmail.com
Country: China
ProdList: 2472
Advantage: 58

Less

View Lastest Price from 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE 399-00-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-07

Henan Bao Enluo International TradeCo.，LTD

Product: 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE 399-00-8
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 10000MT
Release date: 2023-08-17

399-00-8, 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDERelated Search:

5-bromo-2-chloroisonicotinaldehyde

4-Fluoro-5-bromo-2-hydroxybenzaldehyde

5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE

5-Bromo-4-fluoro-2-hydroxybenzaldehyde 98%

Benzaldehyde, 5-bromo-4-fluoro-2-hydroxy-

5-Bromo-4-fluorosalicylaldehyde

399-00-8