5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE

Product Name: 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE
CAS No.: 399-00-8
Chemical Name: 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE
Synonyms: 5-Bromo-4-fluorosalicylaldehyde;4-Fluoro-5-bromo-2-hydroxybenzaldehyde;5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE;Benzaldehyde, 5-bromo-4-fluoro-2-hydroxy-;5-Bromo-4-fluoro-2-hydroxybenzaldehyde 98%
CBNumber: CB2250799
Molecular Formula: C7H4BrFO2
Formula Weight: 219.01
MOL File: Mol file

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5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE Property

Melting point:: 81 °C
Boiling point:: 256.6±35.0 °C(Predicted)
Density: 1.826±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 6.62±0.23(Predicted)
Appearance: Light yellow to pink Solid

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Safety

HS Code: 2913000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B678313
Product name: 5-Bromo-4-fluoro-2-hydroxybenzaldehyde
Packaging: 500mg
Price: $130
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0366994
Product name: 5-BROMO-4-FLUORO-2-HYDROXYBENZALDEHYDE
Purity: 95.00%
Packaging: 1G
Price: $223.65
Updated: 2021/12/16

AK Scientific

Product number: 5262AB
Product name: 5-Bromo-4-fluoro-2-hydroxybenzaldehyde
Packaging: 5g
Price: $316
Updated: 2021/12/16

BroadPharm

Product number: BP-11735
Product name: 5-bromo-4-fluoro-2-hydroxybenzaldehyde
Packaging: 500mg
Price: $375
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2615-B-29
Product name: 5-Bromo-4-fluoro-2-hydroxybenzaldehyde
Packaging: 5G
Price: $396
Updated: 2021/12/16

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5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE Chemical Properties,Usage,Production

Synthesis

348-28-7

399-00-8

The general procedure for the synthesis of 5-bromo-4-fluoro-2-hydroxybenzaldehyde using 4-fluoro-2-hydroxybenzaldehyde as starting material was as follows: a solution of bromine (14.1 g, 88.3 mmol) dissolved in chloroform (25 mL) was added slowly and dropwise over a period of 10 min to a solution of chloroform (68 mL) containing 4-fluoro-2-hydroxybenzaldehyde (13.6 g, 97.1 mmol) in a round bottomed flask. The reaction mixture was stirred at room temperature for 16 hours and then the same amount of bromine (14.1 g) was added. Stirring was continued at room temperature for 24 hours. Upon completion of the reaction, the mixture was washed twice with 30% aqueous sodium thiosulfate to remove the color, followed by washing with water and drying the organic layer with anhydrous sodium sulfate. Finally, the organic phase was concentrated by decompression to afford the target product 5-bromo-4-fluoro-2-hydroxybenzaldehyde (21.3 g, 100% yield).

References

[1] Patent: WO2012/40641, 2012, A2. Location in patent: Page/Page column 135; 136
[2] Journal of Medicinal Chemistry, 2004, vol. 47, # 12, p. 3163 - 3179
[3] Patent: US6642222, 2003, B2
[4] Patent: US6593335, 2003, B1
[5] Patent: WO2013/91096, 2013, A1. Location in patent: Page/Page column 37

5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE Suppliers

China 61 Germany 1 India 1 United Kingdom 3 United States 4 Global 70

Capot Chemical Co., Ltd

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Changzhou Anxuan Chemical, Co., Ltd.

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View Lastest Price from 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE 399-00-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-07

Henan Bao Enluo International TradeCo.，LTD

Product: 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE 399-00-8
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 10000MT
Release date: 2023-08-17

399-00-8, 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDERelated Search:

5-bromo-2-chloroisonicotinaldehyde

4-Fluoro-5-bromo-2-hydroxybenzaldehyde

5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE

5-Bromo-4-fluoro-2-hydroxybenzaldehyde 98%

Benzaldehyde, 5-bromo-4-fluoro-2-hydroxy-

5-Bromo-4-fluorosalicylaldehyde

399-00-8