ChemicalBook > CAS DataBase List > Necrosis Inhibitor, IM-54
Necrosis Inhibitor, IM-54
- Product Name
- Necrosis Inhibitor, IM-54
- CAS No.
- 861891-50-1
- Chemical Name
- Necrosis Inhibitor, IM-54
- Synonyms
- IM-54;IM-54 ,E2178;Necrosis Inhibitor, IM-54;2-(1H-Indol-3-yl)-3-pentylamino-maleimide;IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide);Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem;1-methyl-3-(1-methylindol-3-yl)-4-(pentylamino)pyrrole-2,5-dione;IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide), Necrosis inhibitor;1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-
- CBNumber
- CB22514666
- Molecular Formula
- C19H23N3O2
- Formula Weight
- 325.4
- MOL File
- 861891-50-1.mol
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Necrosis Inhibitor, IM-54 Property
- Boiling point:
- 511.5±50.0 °C(Predicted)
- Density
- 1.20±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble5mg/mL (clear solution)
- form
- Yellow orange solid
- pka
- 1.96±0.20(Predicted)
- color
- light orange to dark orange
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P321Specific treatment (see … on this label).
P405Store locked up.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0412
- Product name
- IM-54
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $203
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 480060
- Product name
- Necrosis Inhibitor, IM-54
- Packaging
- 5mg
- Price
- $226
- Updated
- 2025/07/31
Cayman Chemical
- Product number
- 13323
- Product name
- IM-54
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $31
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 13323
- Product name
- IM-54
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $133
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML0412
- Product name
- IM-54
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $696
- Updated
- 2022/05/15
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Necrosis Inhibitor, IM-54 Chemical Properties,Usage,Production
Uses
Necrosis Inhibitor, IM-54 is a selective inhibitor of oxidative stress-induced necrotic cell death.
Definition
ChEBI: IM-54 is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.
Biological Activity
IM-54 is a cell permeable, potent and selective inhibitor of necrosis. The compound inhibits necrosis induced by oxidative stress. IM-54 does not inhibit apoptosis induced by anticancer drugs.
Necrosis Inhibitor, IM-54 Preparation Products And Raw materials
Raw materials
Preparation Products
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Necrosis Inhibitor, IM-54 Suppliers
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