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tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate

Product Name
tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate
CAS No.
154026-93-4
Chemical Name
tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate
Synonyms
Rosuvastatin Impurity 89;Rosuvastatin Impurity 114;Rosuvastatin Related Compound 5;(3R,5S)-6-Chloro-3,5-dihydroxyhexanoic A;-tert-Butyl 6-chloro-3,5-dihydroxyhexanoate;ert-butyl(3R,5S)-6-chloro-3,5-dihydroxyhexanoate;tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate;(3R,5S)-tert-Butyl 6-chloro-3,5-dihydroxyhexanoate;6-chloro-3,5-dihydroxyhexanoic acid tert-butyl ester;(3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester
CBNumber
CB22520696
Molecular Formula
C10H19ClO4
Formula Weight
238.71
MOL File
154026-93-4.mol
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tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate Property

Melting point:
45-49°C
Boiling point:
364.6±42.0 °C(Predicted)
Density 
1.168±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Solid
pka
13.69±0.20(Predicted)
color 
Pale Beige to Light Beige
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C365815
Product name
(3R,5S)-6-Chloro-3,5-dihydroxyhexanoicAcidtert-ButylEster
Packaging
10g
Price
$215
Updated
2021/12/16
TRC
Product number
C365815
Product name
(3R,5S)-6-Chloro-3,5-dihydroxyhexanoicAcidtert-ButylEster
Packaging
25g
Price
$340
Updated
2021/12/16
AK Scientific
Product number
7729AA
Product name
(3R,5S)-tert-Butyl6-chloro-3,5-dihydroxyhexanoate
Packaging
250mg
Price
$407
Updated
2021/12/16
Matrix Scientific
Product number
096460
Product name
(3R,5S)-tert-Butyl 6-chloro-3,5-dihydroxyhexanoate
Purity
95+%
Packaging
250mg
Price
$265
Updated
2021/12/16
Matrix Scientific
Product number
096460
Product name
(3R,5S)-tert-Butyl 6-chloro-3,5-dihydroxyhexanoate
Purity
95+%
Packaging
1g
Price
$588
Updated
2021/12/16
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tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate Chemical Properties,Usage,Production

Uses

(3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester is an intermediate in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor.

tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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154026-93-4, tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoateRelated Search:

N-[(6R)-8-Fluoro-5,6-dihydro-4-(1-Methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-MethylMethanesulfonaMide 3-Oxo Rosuvastatin SodiuM Salt N-Desmethyl Rosuvastatin Lactone (4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Rosuvastatin ethyl ester Rosuvastatin Impurity 91 Rosuvastatin Related Compound 8 Rosuvastatin Calcium Salt tert-Butyl 2-((4S,6S)-6-(chloromethyl(02,2-1,3-dioxan-4-yl)acetate NGABCYSYENPREI-RYUDHWBXSA-N 4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidine-5-carboxylic acid Rosuvastatin EP Impurity C Rosuvastatin EP impurity H Desfluoro Rosuvastatin Sodium Salt 5-PyriMidinecarboxylic acid, 4-(4-fluorophenyl)-1,2-dihydro-6-(1-Methylethyl)-2-oxo-, Methyl ester Phosphonium, [[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]me Ethyl propionylacetate Rosuvastatin Impurity 4

  • 6-chloro-3,5-dihydroxyhexanoic acid tert-butyl ester
  • Rosuvastatin Related Compound 5
  • Rosuvastatin Impurity 89
  • tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate
  • Hexanoic acid, 6-chloro-3,5-dihydroxy-, 1,1-diMethylethyl ester, (3R,5S)-
  • (3R,5S)-tert-Butyl 6-chloro-3,5-dihydroxyhexanoate
  • (3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester
  • -tert-Butyl 6-chloro-3,5-dihydroxyhexanoate
  • (3R,5S)-6-Chloro-3,5-dihydroxyhexanoic A
  • (3R,5S)-6-Chloro-3,5-dihydroxyhexanoic acid 1,1-dimethylethyl ester
  • Rosuvastatin Impurity 114
  • Hexanoic acid, 6-chloro-3,5-dihydroxy-, 1,1-dimethylethyl es...
  • 154026-93-4 C10H19ClO4 tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate
  • ert-butyl(3R,5S)-6-chloro-3,5-dihydroxyhexanoate
  • (3R,5S)-tert-butyl 6-chloro-3,5-dihydroxyhexanoate? (Rosuvastatin Impurity）
  • (3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester (~90%)
  • 154026-93-4
  • C10H19ClO4