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Ethyl propionylacetate

Product Name
Ethyl propionylacetate
CAS No.
4949-44-4
Chemical Name
Ethyl propionylacetate
Synonyms
ETHYL 3-OXOPENTANOATE;NSC 7251;NSC 78662;ETHYL 3-OXOVALERATE;Ethyl Propioacetate;thyl 3-ketopentanoate;Ethyl3-Oxovalerate>ETHYL PROPIONYLACETATE;Ethyl 3-oxo-n-valerate;Ethyl propanoylacetate
CBNumber
CB0672337
Molecular Formula
C7H12O3
Formula Weight
144.17
MOL File
4949-44-4.mol
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Ethyl propionylacetate Property

Melting point:
98 °C
Boiling point:
83-84 °C/12 mmHg (lit.)
Density 
1.012 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.422(lit.)
Flash point:
172 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Miscible with glacial acetic acid.
form 
Liquid
pka
10.58±0.46(Predicted)
Specific Gravity
1.01
color 
Clear colorless to pale yellow
BRN 
970270
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
UDRCONFHWYGWFI-UHFFFAOYSA-N
CAS DataBase Reference
4949-44-4(CAS DataBase Reference)
NIST Chemistry Reference
Ethyl propionylacetate(4949-44-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29183000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
247162
Product name
Ethyl propionylacetate
Purity
97%
Packaging
5g
Price
$102
Updated
2024/03/01
TCI Chemical
Product number
K0031
Product name
Ethyl 3-Oxovalerate
Purity
>97.0%(GC)
Packaging
5g
Price
$31
Updated
2024/03/01
TCI Chemical
Product number
K0031
Product name
Ethyl 3-Oxovalerate
Purity
>97.0%(GC)
Packaging
25g
Price
$114
Updated
2024/03/01
Alfa Aesar
Product number
A15464
Product name
Ethyl propionylacetate, 95%
Packaging
5g
Price
$72.65
Updated
2024/03/01
Alfa Aesar
Product number
A15464
Product name
Ethyl propionylacetate, 95%
Packaging
25g
Price
$263.65
Updated
2024/03/01
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Ethyl propionylacetate Chemical Properties,Usage,Production

Chemical Properties

colourless liquid

Uses

Ethyl propionylacetate acts as a precursor used in the preparation of 1-ethyl- and 1-n-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid bearing one or two substituents on the benzene ring. Further, it is used to prepare 3-propionyl-2H-cyclohepta[b]furan-2-one.

Uses

Ethyl propionylacetate has been used in the synthesis of 1-ethyl- and 1-n-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid bearing one or two substituents on the benzene ring.

Uses

An intermediate of Rosuvastatin.

Synthesis Reference(s)

Synthesis, p. 829, 1978 DOI: 10.1055/s-1978-24903

General Description

Ethyl propionylacetate reacts with tropolone p-toluenesulfonate in the presence of sodium ethoxide to give 3-propionyl-2H-cyclohepta[b]furan-2-one.

Ethyl propionylacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl propionylacetate Suppliers

Weifang Jiulai Biotechnology Co. LTD
Tel
0536-3600928 18706527771
Email
info@jiulaicn.com
Country
China
ProdList
3
Advantage
58
Wuhan Ying Yuan Bei Biological Limited
Tel
13349903920 13349903920
Email
1540154086@qq.com
Country
China
ProdList
2995
Advantage
58
Chengdu Forest Science and Technology Development Co., Ltd.
Tel
18030648795 18030648795
Fax
028-61777050
Email
sales@cdforestchem.com
Country
China
ProdList
1509
Advantage
58
Zibo Run Hang Seng material Technology Co., LTD
Tel
13561657928 13561657928
Email
2388773670@qq.com
Country
China
ProdList
303
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from Ethyl propionylacetate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ethyl propionylacetate 4949-44-4
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500KGS
Release date
2021-07-03
Xi'an Yutbon Pharmaceutical Technology Co., Ltd
Product
Ethyl propionylacetate 4949-44-4
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-10-09
Hebei Weibang Biotechnology Co., Ltd
Product
Ethyl propionylacetate 4949-44-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-12-13

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