methyl morpholine-2-carboxylate hydrochloride
- Product Name
- methyl morpholine-2-carboxylate hydrochloride
- CAS No.
- 937063-34-8
- Chemical Name
- methyl morpholine-2-carboxylate hydrochloride
- Synonyms
- Methyl morpholine-2-carboxylate, HCl;2-Morpholinecarboxylic acid methyl ester HCl;methyl morpholine-2-carboxylate hydrochloride;2-Morpholinecarboxylic acid methyl ester hydrochloride (1:1)
- CBNumber
- CB22538211
- Molecular Formula
- C6H12ClNO3
- Formula Weight
- 181.62
- MOL File
- 937063-34-8.mol
methyl morpholine-2-carboxylate hydrochloride Property
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- White to off-white Solid
Safety
- RIDADR
- UN2811
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M218788
- Product name
- MethylMorpholine-2-carboxylateHydrochloride
- Packaging
- 10mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 075797
- Product name
- Methyl morpholine-2-carboxylate hydrochloride
- Purity
- 95+%
- Packaging
- 1g
- Price
- $122
- Updated
- 2021/12/16
- Product number
- 4H56-5-JH
- Product name
- Methyl morpholine-2-carboxylate hydrochloride
- Packaging
- 1g
- Price
- $144
- Updated
- 2021/12/16
- Product number
- J90176
- Product name
- Methylmorpholine-2-carboxylatehydrochloride
- Packaging
- 10g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 4H56-5-JH
- Product name
- Methyl morpholine-2-carboxylate hydrochloride
- Packaging
- 5G
- Price
- $424
- Updated
- 2021/12/16
methyl morpholine-2-carboxylate hydrochloride Chemical Properties,Usage,Production
Uses
Methyl Morpholine-2-carboxylate Hydrochloride is used as a preparation of chromen-4-one derivative for the treatment of hepatitis B virus infection.
Synthesis
500789-41-3
937063-34-8
The general procedure for the synthesis of methyl morpholine-2-carboxylate hydrochloride from methyl N-Boc-2-morpholinecarboxylate was as follows: to a solution of 1,4-dioxane (1.0 mL) containing methyl 4-(tert-butoxycarbonyl)-2-morpholinecarboxylate (232 mg, 0.95 mmol) was added a solution of 1,4-dioxane (1.18 mL) with 4 M hydrochloric acid. The reaction mixture was stirred at room temperature for 15 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to afford methyl morpholine-2-carboxylate hydrochloride (232 mg, 0.95 mmol, quantitative yield). The structure of the product was confirmed by 1H NMR (CDCl3) with the following chemical shifts: δ 3.03-3.19 (2H, m), 3.26-3.45 (2H, m), 3.55-3.69 (1H, m), 3.82 (3H, s), 4.03-4.22 (2H, m), 4.58-4.69 (1H, m).
References
[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 9, p. 3072 - 3093
methyl morpholine-2-carboxylate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from methyl morpholine-2-carboxylate hydrochloride manufacturers
- Product
- methyl morpholine-2-carboxylate hydrochloride 937063-34-8
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 95%-98%
- Supply Ability
- 100kg
- Release date
- 2019-09-03