MORPHOLIN-4-YL-ACETIC ACID

Product Name: MORPHOLIN-4-YL-ACETIC ACID
CAS No.: 3235-69-6
Chemical Name: MORPHOLIN-4-YL-ACETIC ACID
Synonyms: 4-Morpholineacetic acid;4-Morpholinylacetic acid;EOS-60962;AKOS BBS-00002525;TIMTEC-BB SBB010303;RARECHEM AL BO 0383;MORPHOLINOACETIC ACID;4-MORPHOLINOACETIC ACID;Carfilzomib Impurity 22;4-Morpholine acetic acid
CBNumber: CB1495292
Molecular Formula: C6H11NO3
Formula Weight: 145.16
MOL File: 3235-69-6.mol

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MORPHOLIN-4-YL-ACETIC ACID Property

Melting point:: 162-164℃
Boiling point:: 272℃
Density: 1.202
Flash point:: 118℃
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 2.25±0.10(Predicted)
color: Off-White
InChI: InChI=1S/C6H11NO3/c8-6(9)5-7-1-3-10-4-2-7/h1-5H2,(H,8,9)
InChIKey: VIWZVFVJPXTXPA-UHFFFAOYSA-N
SMILES: N1(CC(O)=O)CCOCC1
CAS DataBase Reference: 3235-69-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H228Flammable solid

H250Catches fire spontaneously if exposed to air

H260In contact with water releases flammable gases which may ignite spontaneously

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M3601
Product name: 2-Morpholinoacetic Acid
Purity: min. 95.0 %
Packaging: 5G
Price: $99
Updated: 2025/07/31

TRC

Product number: M723690
Product name: Morpholin-4-ylAceticAcid
Packaging: 25g
Price: $355
Updated: 2021/12/16

Matrix Scientific

Product number: 027160
Product name: Morpholin-4-ylacetic acid
Packaging: 25g
Price: $185
Updated: 2021/12/16

AK Scientific

Product number: J94877
Product name: Morpholin-4-yl-aceticacid
Packaging: 25g
Price: $125
Updated: 2021/12/16

Matrix Scientific

Product number: 027160
Product name: Morpholin-4-ylacetic acid
Packaging: 5g
Price: $45
Updated: 2021/12/16

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MORPHOLIN-4-YL-ACETIC ACID Chemical Properties,Usage,Production

Uses

Morpholin-?4-?yl Acetic Acid was used in preparation of pyrrolidine-fused fullerene multicarboxylates by photoreaction.

Definition

ChEBI: N-(2-Carboxymethyl)-morpholine is an alpha-amino acid.

Synthesis

3235-82-3

3235-69-6

b) Synthesis of 2-morpholinoacetic acid Ethyl 2-morpholinoacetate (1 g, 57.8 mmol, 1.0 eq.) was dissolved in 8N HCl and the reaction was stirred at 95°C for 16 hours. Upon completion of the reaction, the reaction mixture was concentrated, quenched, and extracted as in Intermediate Example 15(b). The solvent was removed by distillation to afford the target product 2-morpholinoacetic acid in 96.3% (0.8 g) yield. The product was analyzed by LC-MS (ESI): calculated mass: 145.16; measured mass: 146.3 [M + H]+ (retention time: 0.21 min).

References

[1] Patent: WO2013/53983, 2013, A1. Location in patent: Page/Page column 40
[2] Journal of Medicinal Chemistry, 2000, vol. 43, # 8, p. 1489 - 1494
[3] Liebigs Annalen der Chemie, 1983, # 6, p. 950 - 961
[4] Patent: US2015/11548, 2015, A1. Location in patent: Paragraph 0145
[5] Patent: WO2009/48559, 2009, A1. Location in patent: Page/Page column 70

MORPHOLIN-4-YL-ACETIC ACID Preparation Products And Raw materials

Raw materials

Sodium sulfate Sodium chloride Tetrahydrofuran Ethyl acetate Sodium bicarbonate tert-Butyl bromoacetate Morpholine Sulfuric acid

Preparation Products

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MORPHOLIN-4-YL-ACETIC ACID Suppliers

China 193 Germany 4 India 3 Russia 2 Switzerland 1 United Kingdom 2 United States 22 Global 227

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

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Accela ChemBio Co.,Ltd.

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View Lastest Price from MORPHOLIN-4-YL-ACETIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Morpholin-4-yl-acetic acid 3235-69-6
Price: US $8.80-2.20/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-27

Henan Aochuang Chemical Co.,Ltd.

Product: MORPHOLIN-4-YL-ACETIC ACID 3235-69-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Carfilzomib Impurity 22
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98%
Supply Ability: 500mg
Release date: 2024-07-12

3235-69-6, MORPHOLIN-4-YL-ACETIC ACIDRelated Search:

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Carfilzomib Impurity 22

AKOS BBS-00002525

4-MORPHOLINOACETIC ACID

2-(4-MORPHOLINYL)ACETIC ACID

MORPHOLINOACETIC ACID

MORPHOLIN-4-YL-ACETIC ACID

RARECHEM AL BO 0383

TIMTEC-BB SBB010303

Morpholin-4-ylacetic acid Morpholinoacetic acid

4-Morpholine acetic acid

4-Morpholineacetic acid

morpholin-4-ylacetic acid(SALTDATA: HCl)

2-(Morpholino)acetic acid

N-(Carboxymethyl)morpholine

2-morpholin-4-ium-4-ylacetate

2-morpholin-4-ium-4-ylethanoate

2-morpholin-4-ylethanoic acid

2-(4-morpholin-4-iumyl)acetate

EOS-60962

4-Morpholinylacetic acid

2-morpholin-4-ylaceticaci

Morpholine-4-ylaceticacid

3235-69-6

Carboxylic acid

Amino Acids and Derivatives