ChemicalBook > CAS DataBase List > Peramivir Trihydrate

Peramivir Trihydrate

Product Name
Peramivir Trihydrate
CAS No.
1041434-82-5
Chemical Name
Peramivir Trihydrate
Synonyms
PeraMivir Hydrate;eraMivir;S-021812;Preamivir;BCX-1812,RWJ-270201;Rapiacta trihydrate;BCX 1812 trihydrate;Peramivir Trihydrate;Peramivir Tirhydrate;Peramivir Impurity A
CBNumber
CB22538918
Molecular Formula
C15H30N4O5
Formula Weight
346.43
MOL File
1041434-82-5.mol
More
Less

Peramivir Trihydrate Property

storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
H2O : 6.6 mg/mL (17.26 mM; Need ultrasonic)
form 
Powder
color 
White to off-white
InChIKey
DLIKIAYLVAIOME-KAJZLETJNA-N
SMILES
[C@H]([C@]1([H])[C@@H]([C@@H](C(=O)O)C[C@H]1NC(N)=N)O)(NC(=O)C)C(CC)CC.O |&1:0,1,3,4,9,r|
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2486
Product name
Peramivir trihydrate
Purity
≥98% (HPLC)
Packaging
5mg
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2486
Product name
Peramivir trihydrate
Purity
≥98% (HPLC)
Packaging
25mg
Price
$411
Updated
2024/03/01
ChemScene
Product number
CS-0732
Product name
Peramivir trihydrate
Purity
99.40%
Packaging
50mg
Price
$450
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0019040
Product name
BCX-1812 TRIHYDRATE
Purity
95.00%
Packaging
5MG
Price
$505.4
Updated
2021/12/16
ChemScene
Product number
CS-0732
Product name
Peramivir trihydrate
Purity
99.40%
Packaging
5mg
Price
$80
Updated
2021/12/16
More
Less

Peramivir Trihydrate Chemical Properties,Usage,Production

Uses

Peramivir Trihydrate is a trihydrate of the anti-infection agent Peramivir Trihydrate which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.[1] The IC50 for Peramivir Trihydrate

Definition

ChEBI: A hydrate that is the trihydrate form of peramivir. Used for the treatment of acute uncomplicated influenza in patients 18 years and older who have been symptomatic for no more than two days.

in vitro

Peramivir trihydrate (0.3125-40 μM, 4 h) has nontoxicity to macrophage.
Peramivir trihydrate (2-10 μM, 6-12 h) inhibits cytokine release in LPS-induced hPBMCs.

in vivo

Peramivir trihydrate (20-60 mg/kg, i.p., single dose) inhibits LPS-induced cytokine storm, attenuates acute lung injury and prolongs the survival in cytokine storm syndrome model mice.
Peramivir trihydrate (75 mg/kg, i.m., once a day for 7 days) rescued BALB scid mice from lethal challenge with BR/08 in immunocompromised murine models of infuenza B virus infection.

Peramivir Trihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Peramivir Trihydrate Suppliers

Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
More
Less

View Lastest Price from Peramivir Trihydrate manufacturers

Jinan Jianfeng Chemical Co., Ltd
Product
Peramivir 1041434-82-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1ton
Release date
2024-08-08
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Peramivir trihydrate 1041434-82-5
Price
US $0.00/Kg/Bag
Min. Order
10g
Purity
99min HPLC
Supply Ability
10kg
Release date
2021-08-19
Shaanxi Dideu Medichem Co. Ltd
Product
Peramivir Trihydrate 1041434-82-5
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%min
Supply Ability
20 tons
Release date
2020-05-08

1041434-82-5, Peramivir TrihydrateRelated Search:


  • Peramivir Trihydrate
  • BCX 1812 trihydrate
  • Rapiacta trihydrate
  • RWJ 270201 trihydrate
  • (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic acid hydrate
  • PeraMivir trihydrate/3(R)-[1(S)-AcetaMido-2-ethylbutyl]-4(R)-guanidino-2(S)-hydroxycyclopentane-1(S)-carboxylic acid
  • PeraMivir Hydrate
  • eraMivir
  • (1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentanecarboxylic acid trihydrate
  • BCX-1812,RWJ-270201
  • S-021812
  • RWJ 270201 TRIHYDRATE;BCX 1812 TRIHYDRATE
  • Cyclopentanecarboxylic acid, 3-[(1S)-1-(acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxy-, hydrate (1:3), (1S,2S,3R,4R)-
  • (1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentane-1-carboxylic acid trihydrate
  • Peramivir Tirhydrate
  • (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic acid trihydrate
  • Peramivir Impurity A
  • Peramivir Trihydrate (RWJ-270201
  • Paramivir trihydrate
  • Preamivir
  • (1S,2S,3R,4R)-3-[(1S)-1-(acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxy-Cyclopentanecarboxylic acid hydrate (1:3)
  • Paramivir impurity A
  • 1041434-82-5
  • C15H34N4O7
  • C15H36N4O8
  • C15H28N4O43H2O
  • Inhibitors
  • API
  • 1041434-82-5