ChemicalBook > CAS DataBase List > Vilanterol

Vilanterol

Product Name
Vilanterol
CAS No.
503068-34-6
Chemical Name
Vilanterol
Synonyms
CS-1833;GW642444;GW-642444;GW 642444;Vianterol;Vilantero;GW 642444X;Vilanterol;Vilanterol API;Vilanterol base
CBNumber
CB22542797
Molecular Formula
C24H33Cl2NO5
Formula Weight
486.43
MOL File
503068-34-6.mol
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Vilanterol Property

Boiling point:
646.7±55.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
solution in ethanol
pka
9.99±0.20(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H370Causes damage to organs

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P307+P311IF exposed: call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20702
Product name
Vilanterol
Purity
≥98%
Packaging
500μg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
20702
Product name
Vilanterol
Purity
≥98%
Packaging
1mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
20702
Product name
Vilanterol
Purity
≥98%
Packaging
5mg
Price
$266
Updated
2024/03/01
AK Scientific
Product number
5959CR
Product name
Vilanterol
Packaging
5mg
Price
$394
Updated
2021/12/16
ApexBio Technology
Product number
B1005
Product name
Vilanterol
Packaging
10mg
Price
$527
Updated
2021/12/16
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Vilanterol Chemical Properties,Usage,Production

Definition

ChEBI: An dichlorobenzene derivative that is used in the form of its trifenate salt for treatment of chronic obstructive pulmonary disease.

Biological Activity

vilanterol is a novel and selective agonist of β2-ar with a pec50 value of 10.37±0.05 [1].vilanterol is a novel long-acting β2-ar agonist (laba) with 24h activity in development for inhaled once daily treatment. in the radioligand binding studies, vilanterol has shown the binding affinity in the one-affinity site model with pkd values of 9.44±0.07 and 10.82±0.12 in the presence gpp(nh)p and absence gpp(nh)p, respectively. in dissociation studies, vilanterol has been reported to bind from the β2-ar with a dissociation t1/2 value of 3.5 min in the presence of gpp(nh)p. vilanterol has been found to have a good selectivity for β2-ar over the other β-ar receptor subtypes(β1and β3) with pec50 values of 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively. vilanterol has exhibited at least 1000-fold selectivity over both β1-and β3-ar subtypes [1].

References

[1] slack rj1, barrett vj, morrison vs, sturton rg, emmons aj, ford aj, knowles rg.in vitro pharmacological characterization of vilanterol, a novel long-acting β2-adrenoceptor agonist with 24-hour duration of action.j pharmacol exp ther. 2013 jan; 344(1):218-30.

Vilanterol Preparation Products And Raw materials

Raw materials

Preparation Products

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Vilanterol Suppliers

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View Lastest Price from Vilanterol manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
Vilanterol 503068-34-6
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-07
Wuhan Xinhao Biotechnology Co., Ltd
Product
Vilanterol 503068-34-6
Price
US $10.00-100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2024-03-11
Anhui Zhongda Biotechnology Co., Ltd
Product
Vilanterol 503068-34-6
Price
US $10.00/g
Min. Order
1g
Purity
99%
Supply Ability
500tons
Release date
2023-10-18

503068-34-6, VilanterolRelated Search:


  • Vilanterol
  • GW 642444X
  • Vilanterol API
  • GW 642444
  • GW642444
  • GW-642444
  • 4-[(R)-2-[[6-[2-(2,6-Dichlorobenzyloxy)ethoxy]hexyl]amino]-1-hydroxyethyl]-2-hydroxymethylphenol
  • Vilanterol(GW642444)
  • GW 642444X Vilanterol
  • 4-{(1R)-2-[(6-{2-[(2,6-Dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
  • Vilanterol base
  • Vianterol
  • Widely Used Vilanterol
  • CS-1833
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  • Genipin 1-β-gentiobioside
  • Vilanterol - API Standards
  • 503068-34-6
  • 50070-58-4
  • 503086-34-6
  • C24H33Cl2NO5
  • Inhibitors
  • Intermediate
  • 503068-34-6