4-Hydroxy-3-nitrobenzotrifluoride
- Product Name
- 4-Hydroxy-3-nitrobenzotrifluoride
- CAS No.
- 400-99-7
- Chemical Name
- 4-Hydroxy-3-nitrobenzotrifluoride
- Synonyms
- 4-Hydroxy-3-nitroben;alpha,alpha,alpha-trifluoro-2;2-nitro-4-trifluoromethlphenol;5-Nitro-2-trifluoromethyl-phenol;2-Nitro-4-(trifluormethyl)phenol;4-HYDROXY-3-NITROBENZOTRIFLUORIDE;2-nitro-4-(trifluoromethyl)-pheno;2-NITRO-4-(TRIFLUOROMETHYL)PHENOL;4-HYDROXY-3-NITROBENZOTRIFLUOROIDE;3-nitro-4-hydroxy-benzotrifluoride
- CBNumber
- CB2254964
- Molecular Formula
- C7H4F3NO3
- Formula Weight
- 207.11
- MOL File
- 400-99-7.mol
4-Hydroxy-3-nitrobenzotrifluoride Property
- Boiling point:
- 92-94 °C12 mm Hg(lit.)
- Density
- 1.473 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.504(lit.)
- Flash point:
- 203 °F
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Liquid
- pka
- 5.53±0.14(Predicted)
- color
- Yellow to orange
- BRN
- 2215510
- CAS DataBase Reference
- 400-99-7(CAS DataBase Reference)
- EPA Substance Registry System
- Phenol, 2-nitro-4-(trifluoromethyl)- (400-99-7)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-36
- WGK Germany
- 3
- RTECS
- GP2984950
- TSCA
- T
- HazardClass
- IRRITANT
- HS Code
- 29089990
- Toxicity
- LD50 ipr-mus: 800 mg/kg JPMSAE 57,1763,68
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 238759
- Product name
- 2-Nitro-4-(trifluoromethyl)phenol
- Purity
- 99%
- Packaging
- 1G
- Price
- $49
- Updated
- 2023/01/07
- Product number
- N0779
- Product name
- 2-Nitro-4-(trifluoromethyl)phenol
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $46
- Updated
- 2025/07/31
- Product number
- N0779
- Product name
- 2-Nitro-4-(trifluoromethyl)phenol
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $148
- Updated
- 2025/07/31
- Product number
- N900803
- Product name
- 2-Nitro-4-(trifluoromethyl)phenol
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 001467
- Product name
- 4-Hydroxy-3-nitrobenzotrifluoride
- Purity
- 97%
- Packaging
- 5g
- Price
- $77
- Updated
- 2021/12/16
4-Hydroxy-3-nitrobenzotrifluoride Chemical Properties,Usage,Production
Uses
2-Nitro-4-(trifluoromethyl)phenol has been used in the synthesis of 2-methyl-2-[2-nitro-4-(trifluoromethyl)phenoxy]propionic acid ethyl ester.
General Description
2-Nitro-4-(trifluoromethyl)phenol is the major product of solution phase photodecomposition of fluorodifen.
Safety Profile
Moderately toxic byintraperitoneal route. When heated to decomposition itemits toxic vapors of NOx and Fí.
Synthesis
139-07-1
121-17-5
400-99-7
Example 1: 400 mL of methanol, 20 g of dodecyldimethylbenzylammonium chloride and 180 g of 4-chloro-3-nitrobenzotrifluoride were added to a reaction flask with stirring turned on. Subsequently, 400 g of 50% sodium hydroxide solution was slowly added dropwise, with the dropwise acceleration controlled to raise the reaction temperature to 70°C in about 20 minutes. The reaction mixture was continued stirring at 65°C for 4 hours. Upon completion of the reaction, the mixture was cooled in an ice water bath and the pH was adjusted with concentrated hydrochloric acid to 3. 2-Nitro-4-trifluoromethylphenol was isolated by steam distillation, and about 50 mL of concentrated hydrochloric acid was added to the receiver to facilitate phase separation. After gas chromatographic analysis, 156 g of 2-nitro-4-trifluoromethylphenol was obtained with a purity of >98.5% and a yield of 91% of the theoretical value. The boiling point of the product was 92 °C-95 °C (15 mmHg) and the refractive index nD20 was 1.5020.
References
[1] Patent: US4225731, 1980, A
4-Hydroxy-3-nitrobenzotrifluoride Preparation Products And Raw materials
Raw materials
Preparation Products
4-Hydroxy-3-nitrobenzotrifluoride Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
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- 28387
- Advantage
- 80
View Lastest Price from 4-Hydroxy-3-nitrobenzotrifluoride manufacturers
- Product
- 4-Hydroxy-3-nitrobenzotrifluoride 400-99-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-11-28
- Product
- 4-Hydroxy-3-nitrobenzotrifluoride 400-99-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 50mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-08
- Product
- 4-Hydroxy-3-nitrobenzotrifluoride 400-99-7
- Price
- US $1.00-12.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2024-07-26