ChemicalBook > CAS DataBase List > 2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole
2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole
Reaction- Product Name
- 2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole
- CAS No.
- 1067883-58-2
- Chemical Name
- 2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole
- Synonyms
- CM-Phos;2-[2-(Dicyclohexylphosphino)phenyl]-N-methylindole;2-[2-(dicyclohexylphosphanyl)phenyl]-1-methylindole;2-(2-(dicyclohexylphosphino)phenyl)-1-Methyl-indole;dicyclohexyl-[2-(1-methylindol-2-yl)phenyl]phosphane;2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indol;2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole;2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole;2-[2-(Dicyclohexylphosphino)phenyl]-N-methylindole 97%;1H-Indole, 2-[2-(dicyclohexylphosphino)phenyl]-1-methyl-
- CBNumber
- CB22549862
- Molecular Formula
- C27H34NP
- Formula Weight
- 403.54
- MOL File
- 1067883-58-2.mol
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2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole Property
- Melting point:
- 180-185℃
- Boiling point:
- 582.4±33.0 °C(Predicted)
- form
- Powder
- color
- white to off-white
- InChI
- 1S/C27H34NP/c1-28-25-18-10-8-12-21(25)20-26(28)24-17-9-11-19-27(24)29(22-13-4-2-5-14-22)23-15-6-3-7-16-23/h8-12,17-20,22-23H,2-7,13-16H2,1H3
- InChIKey
- PFJAHDIIEPTASS-UHFFFAOYSA-N
- SMILES
- Cn1c(cc2ccccc12)-c3ccccc3P(C4CCCCC4)C5CCCCC5
- CAS DataBase Reference
- 1067883-58-2
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Safety
- WGK Germany
- 3
- Storage Class
- 11 - Combustible Solids
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 752231
- Product name
- 2-[2-(Dicyclohexylphosphino)phenyl]-N-methylindole
- Purity
- 97%
- Packaging
- 250mg
- Price
- $325
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 752231
- Product name
- 2-[2-(Dicyclohexylphosphino)phenyl]-N-methylindole
- Purity
- 97%
- Packaging
- 1g
- Price
- $628.36
- Updated
- 2025/07/31
TCI Chemical
- Product number
- D5509
- Product name
- 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole
- Purity
- min. 97.0 %
- Packaging
- 200MG
- Price
- $75
- Updated
- 2025/07/31
TCI Chemical
- Product number
- D5509
- Product name
- 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole
- Purity
- min. 97.0 %
- Packaging
- 1G
- Price
- $226
- Updated
- 2025/07/31
Strem Chemicals
- Product number
- 15-1088
- Product name
- 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole, min. 98% CM-Phos
- Packaging
- 100mg
- Price
- $45
- Updated
- 2024/03/01
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2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole Chemical Properties,Usage,Production
Reaction
- Suzuki-Miyaura Coupling of Aryl Mesylates and alkenyl tosylate and mesylate bearing alkyl, methoxy, aldehyde, keto, nitrile, ester, and heteroaryl substitution.
- Sonogashira Coupling of Aryl Mesylates, R' = alkyl, aryl; R = C(O)R, COOMe, CHO, CN.
- Buchwald-Hartwig Amination of Aryl Mesylates, R = cyano, chloro, methoxy, keto, ester and etc.
- Additional catalyzed reactions include Cyanation of functional Aryl Mesylates and Chlorides; Hiyama Coupling of Aryl Mesylates; Direct Arylation of Heterocycles with Aryl Mesylates; Borylation of Aryl Mesylates.
Uses
2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole (CM-Phos) is an organic compound with catalytic activity. 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole can be used as an efficient catalyst for cross-coupling reactions of various alcohols and olefins. 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole shows important application potential in pharmaceutical and material science.
reaction suitability
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
Synthesis
2-(2-DicyclohexylphosphaNYL-phenyl)-1-methyl-1H-indole can be prepared in one step from N-methyl-2-phenyl-3-bromoindole with chlorodicyclohexylphosphine.
2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole Preparation Products And Raw materials
Raw materials
Preparation Products
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2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole Suppliers
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