ChemicalBook > CAS DataBase List > 6-Chloro-1H-pyrazolo[4,3-c]pyridine

6-Chloro-1H-pyrazolo[4,3-c]pyridine

Product Name: 6-Chloro-1H-pyrazolo[4,3-c]pyridine
CAS No.: 1206979-33-0
Chemical Name: 6-Chloro-1H-pyrazolo[4,3-c]pyridine
Synonyms: 100587;6-Chloro-5-azaindazole;6-chloro-pyrazolo[4,3-c]pyridine;6-chloro-1H-pyrazolo[4,4-c]pyridine;6-Chloro-1H-pyrazolo[4,3-c]pyridine;1H-Pyrazolo[4,3-c]pyridine, 6-chloro-;6-Chloro-1H-Pyrazolo[4,3-C]Pyridine(WXC01805);6-Chloro-1H-pyrazolo[4,3-c]pyridine
CBNumber: CB22550110
Molecular Formula: C6H4ClN3
Formula Weight: 153.57
MOL File: 1206979-33-0.mol

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6-Chloro-1H-pyrazolo[4,3-c]pyridine Property

Boiling point:: 358℃
Density: 1.531
Flash point:: 201℃
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder
pka: 10.46±0.40(Predicted)
color: Yellow
InChI: InChI=1S/C6H4ClN3/c7-6-1-5-4(2-8-6)3-9-10-5/h1-3H,(H,9,10)
InChIKey: AAJIQIWPVIWCGA-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=CC2NN=CC1=2
CAS DataBase Reference: 1206979-33-0

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HS Code: 2933790090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BLN00009
Product name: 6-Chloro-1H-pyrazolo[4,3-c]pyridine
Packaging: 1g
Price: $783
Updated: 2025/07/31

TRC

Product number: C380833
Product name: 6-Chloro-1H-pyrazolo[4,3-c]pyridine
Packaging: 500mg
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: X9434
Product name: 6-Chloro-1H-pyrazolo[4,3-c]pyridine
Packaging: 250mg
Price: $38
Updated: 2021/12/16

Matrix Scientific

Product number: 084107
Product name: 6-Chloro-1H-pyrazolo[4,3-c]pyridine
Purity: 97%
Packaging: 1g
Price: $185
Updated: 2021/12/16

AK Scientific

Product number: J97063
Product name: 6-Chloro-1H-pyrazolo[4,3-c]pyridine
Packaging: 5g
Price: $200
Updated: 2021/12/16

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6-Chloro-1H-pyrazolo[4,3-c]pyridine Chemical Properties,Usage,Production

Uses

Used as a pharmaceutical intermediate for laboratory research and development.

Synthesis

4,6-Dichloropyridine-3-carbaldehyde (3.7 g, 32 mmol), hydrazine (3.5 mL, 110 mmol) and N,N-diisopropylethylamine (20 mL) were combined in DMA (100 mL) and stirred at 80° C. for four hours. Then, the solution was cooled to room temperature, diluted with EtOAc, and washed three times with water and then with brine. The organic solution was concentrated and the resulting mixture was precipitated from dichloromethane to give 6-chloro-1H-pyrazolo[4,3-c]pyridine. Yield 2 g (41%). LCMS (ESI): calc. C6H4ClN3=153; obs. M+H=154.

References

[1] Patent: WO2015/38417, 2015, A1. Location in patent: Page/Page column 78
[2] Patent: WO2013/169704, 2013, A2. Location in patent: Paragraph 0232
[3] Patent: WO2014/210354, 2014, A1. Location in patent: Page/Page column 41
[4] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 20, p. 5648 - 5652

6-Chloro-1H-pyrazolo[4,3-c]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-Chloro-1H-pyrazolo[4,3-c]pyridine manufacturers

Career Henan Chemical Co

Product: 6-Chloro-1H-pyrazolo[4,3-c]pyridine 1206979-33-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2018-08-06

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