6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE

Product Name: 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
CAS No.: 55052-27-2
Chemical Name: 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
Synonyms: 6-CHLORO-7-AZAINDOLE;6-chloro-;o[2,3-b]pyridine;6-Chloro-7-azaindole,95%;2-Chloro-7H-pyrrolo[2,3-b]pyridine;6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE;1H-Pyrrolo[2,3-b]pyridine, 6-chloro-;6-Chloro-1H-pyrrolido [2,3-B] pyridine;6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE ISO 9001：2015 REACH
CBNumber: CB8360793
Molecular Formula: C7H5ClN2
Formula Weight: 152.58
MOL File: 55052-27-2.mol

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6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE Property

Melting point:: 170-175℃
Boiling point:: 420.7±37.0 °C(Predicted)
Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 6.76±0.40(Predicted)
form: Powder
color: White to pale brown
InChI: InChI=1S/C7H5ClN2/c8-6-2-1-5-3-4-9-7(5)10-6/h1-4H,(H,9,10)
InChIKey: DSCOSIUAQUDGJM-UHFFFAOYSA-N
SMILES: C12NC=CC1=CC=C(Cl)N=2

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-39
RIDADR: UN2811
HazardClass: 6.1
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: B418665
Product name: 6-Chloro-1H-pyrrolo[2,3-b]pyridine
Packaging: 5g
Price: $150
Updated: 2021/12/16

Apolloscientific

Product number: OR301275
Product name: 6-Chloro-1H-pyrrolo[2,3-b]pyridine
Packaging: 5g
Price: $174
Updated: 2021/12/16

AK Scientific

Product number: V2201
Product name: 6-Chloro-7-azaindole
Packaging: 10g
Price: $181
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC140689
Product name: 6-Chloro-7-azaindole
Packaging: 2g
Price: $100
Updated: 2021/12/16

Matrix Scientific

Product number: 070121
Product name: 6-Chloro-1H-pyrrolo[2,3-b]pyridine
Purity: 95%
Packaging: 5g
Price: $140
Updated: 2021/12/16

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6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE Chemical Properties,Usage,Production

Uses

6-Chloro-1H-pyrrolo[2,3-b]pyridine is used in the preparation of heterocyclic compounds for the use of treatment of cancer.

Synthesis

849068-50-4

55052-27-2

Example 96 Step C: Synthesis of 6-chloro-1H-pyrrolo[2,3-B]pyridine. Ethyl 6-chloro-pyrrolo[2,3-B]pyridine-1-carboxylate (400 mg, 1.78 mmol) was dissolved in methanol (35 mL), followed by the addition of 1N sodium hydroxide solution (13 mL). The reaction mixture was stirred at room temperature for 6 hours. Upon completion of the reaction, the solvent was removed by rotary evaporator. The residue was neutralized with saturated sodium bicarbonate solution and the precipitate was collected by filtration. The precipitate was washed with water and dried by vacuum pump to afford the target product 6-chloro-1H-pyrrolo[2,3-B]pyridine (260 mg, 1.71 mmol, 96% yield). MS (electrospray positive ion mode): m/e = 153.1 ([M+H]+); LC retention time: 2.85 min.

References

[1] Patent: WO2005/28475, 2005, A2. Location in patent: Page/Page column 175
[2] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 23, p. 7107 - 7112
[3] Patent: WO2013/10880, 2013, A1. Location in patent: Page/Page column 103-104
[4] Patent: EP2548876, 2013, A1. Location in patent: Paragraph 0438-0441
[5] Patent: WO2016/112088, 2016, A1. Location in patent: Paragraph 0447

6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE Preparation Products And Raw materials

Raw materials

7-Azaindole 3-Chloroperoxybenzoic acid Benzyl bromide Hexamethyldisilazane

Preparation Products

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6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE Suppliers

China 198 Germany 2 India 3 United Kingdom 2 United States 11 Global 216

Hebei Maipu Technology Co., LTD

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Energy Chemical

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Pure Chemistry Scientific Inc.

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Adamas Reagent, Ltd.

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View Lastest Price from 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE manufacturers

Hebei Zhanyao Biotechnology Co. Ltd

Product: 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE 55052-27-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-10-14

Dideu Industries Group Limited

Product: 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE 55052-27-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-22

Career Henan Chemical Co

Product: 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE 55052-27-2
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-03

55052-27-2, 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINERelated Search:

O-METHYLVALEROLACTIM 4,6-DICHLORO-1H-PYRROLO-[3,2-C]-PYRIDINE ethyl 5-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate METHYL 6-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE-3-CARBOXYLATE 4-Chloro-1H-pyrrolo[2,3-β]pyridine,4-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE 3-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE 6-chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro- 5-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine 4-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID 5-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid 3-bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine 6-Chloro-1,3-dihydro-2H-pyrrolo[3,2-c]pyridin-2-one 6-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid ethyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 6-chloro- 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE ethyl 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate

6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE

6-CHLORO-7-AZAINDOLE

1H-Pyrrolo[2,3-b]pyridine, 6-chloro-

6-chloro-

2-Chloro-7H-pyrrolo[2,3-b]pyridine

o[2,3-b]pyridine

6-Chloro-7-azaindole,95%

6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE ISO 9001：2015 REACH

6-Chloro-1H-pyrrolido [2,3-B] pyridine

55052-27-2

55050-27-2

Pyridines