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Benzyl glycinate p-toluenesulfonate

Product Name
Benzyl glycinate p-toluenesulfonate
CAS No.
1738-76-7
Chemical Name
Benzyl glycinate p-toluenesulfonate
Synonyms
H-GLY-OBZL TOSOH;GLYCINE BENZYL ESTER P-TOLUENESULFONATE SALT;ycine toL;uene-p-suL;GLY-OBZL TOS;GLY-OBZL TSOH;H-GLY-OBZL TOS;Gly-OBzl·TosOH;Einecs 217-094-6;H-Gly-OBzl-tosylate
CBNumber
CB2256973
Molecular Formula
C16H19NO5S
Formula Weight
337.39
MOL File
1738-76-7.mol
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Benzyl glycinate p-toluenesulfonate Property

Melting point:
132-134 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
methanol: 0.1 g/mL, clear
form 
Solid
color 
White to Off-White
Water Solubility 
almost transparency
BRN 
3600116
InChI
InChI=1S/C9H11NO2.C7H8O3S/c10-6-9(11)12-7-8-4-2-1-3-5-8;1-6-2-4-7(5-3-6)11(8,9)10/h1-5H,6-7,10H2;2-5H,1H3,(H,8,9,10)
InChIKey
WJKJXKRHMUXQSL-UHFFFAOYSA-N
SMILES
C1(S(O)(=O)=O)=CC=C(C)C=C1.C(OCC1=CC=CC=C1)(=O)CN
CAS DataBase Reference
1738-76-7(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
50051
Product name
Glycine benzyl ester p-toluenesulfonate salt
Purity
≥99.0% (T)
Packaging
25g
Price
$219
Updated
2025/07/31
TCI Chemical
Product number
B0266
Product name
Glycine Benzyl Ester p-Toluenesulfonate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$16
Updated
2025/07/31
TCI Chemical
Product number
B0266
Product name
Glycine Benzyl Ester p-Toluenesulfonate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$36
Updated
2025/07/31
TRC
Product number
G625100
Product name
Glycine Benzyl Ester p-Toluenesulfonate
Packaging
25g
Price
$100
Updated
2021/12/16
TRC
Product number
G625100
Product name
Glycine Benzyl Ester p-Toluenesulfonate
Packaging
100g
Price
$375
Updated
2021/12/16
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Benzyl glycinate p-toluenesulfonate Chemical Properties,Usage,Production

Chemical Properties

White crystalline

Uses

Potent crosslinking inhibitors

Uses

Racecodotril intermediate

Uses

Glycine benzyl ester p-toluenesulfonate salt is a potent crosslinking inhibitor.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

104-15-4

56-40-6

100-51-6

1738-76-7

General procedure: 270 kg of p-toluenesulfonic acid monohydrate and 550 kg of toluene are added to the reactor, stirring is initiated and heating is brought to reflux. The water generated by the reaction was removed by means of a water separator until no water was produced. Subsequently, glycine was added to the reaction vessel. Continue to add 100 kg of reaction solution and 850 kg of benzyl alcohol to the reaction system and maintain reflux. The water generated from the reaction was continuously separated through a water separator until no water was generated, and then the reaction was continued at reflux for 2 hours. Upon completion of the reaction, the reaction solution was cooled to 10°C and stirred for 1 hour. The reaction mixture was filtered and the filter cake was washed with 100 kg of acetone and dried to give 395 kg of glycine benzyl ester p-toluenesulfonate in 88.4% yield and 99.62% purity.

References

[1] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 2, p. 519 - 532
[2] Synthesis, 2002, # 8, p. 1017 - 1026
[3] Chemical Communications, 2007, # 36, p. 3711 - 3713
[4] Chemistry - An Asian Journal, 2009, vol. 4, # 2, p. 328 - 335
[5] Journal of Heterocyclic Chemistry, 1994, vol. 31, # 4, p. 707 - 710

Benzyl glycinate p-toluenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzyl glycinate p-toluenesulfonate Suppliers

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View Lastest Price from Benzyl glycinate p-toluenesulfonate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Benzyl glycinate p-toluenesulfonate 1738-76-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg/month
Release date
2021-12-27
Hebei Chuanghai Biotechnology Co,.LTD
Product
Benzyl Glycinate P-Toluenesulfonate 1738-76-7
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-20
Hangzhou ICH Biofarm Co., Ltd
Product
Glycine benzyl ester p-toluenesulfonate salt 1738-76-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99.0%min
Supply Ability
5MT
Release date
2023-06-14

1738-76-7, Benzyl glycinate p-toluenesulfonateRelated Search:

Betaine p-Toluenesulfonic acid Glycine Benzyl nicotinate Benzyl benzoate Sodium xylenesulfonate Sorafenib tosylate Benzyl chloride Benzyl alcohol Sodium p-toluenesulfonate SODIUM P-TOLUENESULFONATE H-D-PRO-OBZL HCL H-GLY-PHE-GLY-OH GLYCYL-L-PHENYLALANINE H-GLY-PHE-PNA HCL Benzyl glycinate hydrochloride GLYCYL-SARCOSINE Glycine tert butyl ester hydrochloride

  • BENZYL GLYCINATE 4-TOLUENESULFONATE SALT
  • BENZYL GLYCINATE P-TOLUENESULFONATE SALT
  • GLY-OBZL TOS
  • GLY-OBZL TSOH
  • GLYCINE-OBZL P-TOSYLATE
  • GLYCINE BENZYL ESTER 4-TOLUENESULFONATE
  • GLYCINE BENZYL ESTER 4-TOLUENESULFONATE SALT
  • GLYCINE BENZYL ESTER 4-TOSYLATE
  • GLYCINE BENZYL ESTER MONOTOSYLATE
  • GLYCINE BENZYL ESTER P-TOLUENESULFONATE
  • GLYCINE BENZYL ESTER P-TOLUENESULFONATE SALT
  • AMinoacetic acid benzyl ester toluene-4-sulfonic acid salt
  • benzyl 2-aMinoacetate 4-Methylbenzenesulfonate
  • Product NaMe: Glycine benzyl ester p-toluenesulfonate salt
  • Benzyl glycinate toluene-p-sulphonate
  • Benzyl 2-aminoacetate p-toluenesulfonate
  • Racecadotril Impurity P
  • Glycine benzyl ester 4-toluenesulfonate salt≥ 98% (HPLC)
  • 2-aminoacetic acid (phenylmethyl) ester
  • GLYCINE BENZYL ESTER P-TOSYLATE
  • GLYCINE BENZYL ESTER PTSA
  • GLYCINE BENZYL ESTER TOLUENE-4-SULFONATE
  • GLYCINE BENZYL ESTER TOLUENE-P-SULFONATE
  • GLYCINE BENZYL ESTER TOSYLATE
  • H-GLY-OBZL P-TOSYLATE
  • H-GLY-OBZL TOS
  • H-GLY-OBZL TOSOH
  • L-GLYCINE BENZYL ESTER P-TOLUENESULFONATE SALT
  • Gly-OBzl·TosOH
  • O-benzylglycine toluene-p-sulphonate
  • Glycine benzyl ester p-toluenesulfonate salt(H-Gly-Obzl-TosOH)
  • Glycinebenzylester·Tos,Glycinebenzylesterp-toluenesulfonate
  • Benzyl glycinate p-toluenesulfonate
  • H-Gly-OBzl-tosylate
  • Glycine benzyl·p-toluenesulfonic acid
  • H-Gly-OBzl . p-tosylate (Glycine benzyl ester.4-toluenesulfonate salt)
  • Einecs 217-094-6
  • Benzyl glycinate p-t
  • H-Gly-OBzl.p-tosylate (Glycine benzyl ester.para toluene sulfonate)
  • Glycine Toluenesulfonate
  • Glycine Benzyl Ester p-Toluenesulfonate &gt
  • glycine benzyl ester to toluene sulfonate
  • uene-p-suL
  • ycine toL
  • Glycine, phenylmethyl ester, 4-methylbenzenesulfonate (1:1)
  • Glycinebenzylesterp-toluenesulfonatesal
  • Benzyl glycinate p-toluenesulfonate USP/EP/BP
  • (2-oxo-2-phenylmethoxyethyl)azanium
  • Glycine benzyl ester p-toluenesulphonate, 98%
  • Glycine Benzyl Ester p-Toluene Sulfonate extrapure, 98%
  • Benzyl glycinate tosylate
  • Benzyl glycinate 4-methylbenzenesulfonate
  • Glycine benzyl ester <i>p</i>-toluenesulfonate salt
  • Benzyl glycite p-toluenesulfote
  • 1738-76-7
  • 1783-76-7
  • C9H11NO2C7H8SO3
  • C9H11NO2C7H8O3S