Glycine tert butyl ester hydrochloride
- Product Name
- Glycine tert butyl ester hydrochloride
- CAS No.
- 27532-96-3
- Chemical Name
- Glycine tert butyl ester hydrochloride
- Synonyms
- GLYCINE TERT-BUTYL ESTER HYDROCHLORIDE;TERT-BUTYL GLYCINATE HYDROCHLORIDE;Gly-OtBu.HCl;H-GLY-OTBU HCL;tert-Butyl glycine hydrochloride;H-GLY-OBUT HCL;L-Gly-Otbu.Hcl;GLYCINE-OTBU HCL;L-H-Gly-OtBu HCL;t-Butyl glycinate
- CBNumber
- CB4122719
- Molecular Formula
- C6H14ClNO2
- Formula Weight
- 167.63
- MOL File
- 27532-96-3.mol
Glycine tert butyl ester hydrochloride Property
- Melting point:
- 141-143 °C(lit.)
- storage temp.
- -20°C
- solubility
- H2O: 0.1 g/mL, clear, colorless
- form
- Crystalline Powder
- color
- White
- Water Solubility
- Soluble in methanol and water
- BRN
- 3989048
- Major Application
- peptide synthesis
- InChI
- InChI=1S/C6H13NO2.ClH/c1-6(2,3)9-5(8)4-7;/h4,7H2,1-3H3;1H
- InChIKey
- OSWULUXZFOQIRU-UHFFFAOYSA-N
- SMILES
- C(C)(C)(C)OC(=O)CN.Cl
- CAS DataBase Reference
- 27532-96-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 347957
- Product name
- Glycine tert-butyl ester hydrochloride
- Purity
- 97%
- Packaging
- 1g
- Price
- $25.8
- Updated
- 2025/07/31
- Product number
- 347957
- Product name
- Glycine tert-butyl ester hydrochloride
- Purity
- 97%
- Packaging
- 5g
- Price
- $40.19
- Updated
- 2025/07/31
- Product number
- 42604
- Product name
- Glycine tert-butyl ester hydrochloride
- Purity
- puriss., ≥99.0% (AT)
- Packaging
- 1g
- Price
- $37.2
- Updated
- 2022/05/15
- Product number
- 42604
- Product name
- Glycine tert-butyl ester hydrochloride
- Purity
- puriss., ≥99.0% (AT)
- Packaging
- 5G
- Price
- $67.7
- Updated
- 2022/05/15
- Product number
- G0254
- Product name
- Glycine tert-Butyl Ester Hydrochloride
- Purity
- >98.0%(N)(T)
- Packaging
- 1g
- Price
- $22
- Updated
- 2025/07/31
Glycine tert butyl ester hydrochloride Chemical Properties,Usage,Production
Chemical Properties
Glycine tert butyl ester hydrochloride is Crystalline
Uses
Glycine tert butyl ester hydrochloride is a substituted Glycine (G615990) used as parakeratosis inhibitor and external composition for skin.
Uses
Glycine t-butyl ester hydrochloride is a substituted Glycine used as parakeratosis inhibitor.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
Add 1400L of tert-butyl acetate, 105KG of glycine to 2000L reaction tank, and add 180KG of perchloric acid at a uniform rate. Reaction at 0-10 ?? about 48-72 hours, the reaction process TLC to monitor the reverse situation, to be glycine reaction more than 90%, with 4 N sodium hydroxide aqueous solution to adjust the PH6.5-7.5, separated from the organic layer, the aqueous layer continues to be extracted with tert-butyl acetate, to be basically extracted to 95% of the products of water, combined with all the product layer, to be extracted to 95% of the product, and the water layer, to be extracted to 95% of the product. After 95% of the product was extracted, all the product layers were combined and washed with brine to TLC pure, then 1500L of tert-butyl glycinate / tert-butyl ethyl ester solution was obtained, tert-butyl glycinate was concentrated and recycled to obtain tert-butyl glycinate 180KG, 100L of ethyl ethyl ester was added, and the product was passed through the HCl to PH0.5, then stirred to cool and cold crystallize, and centrifugally washed to obtain tert-butyl glycinate hydrochloride 182KG.
Glycine tert butyl ester hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Glycine tert butyl ester hydrochloride manufacturers
- Product
- Glycine tert butyl ester hydrochloride 27532-96-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%-102%
- Supply Ability
- 10 tons
- Release date
- 2025-12-17
- Product
- H-Gly-Otbu.Hcl 27532-96-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-03-26
- Product
- Glycine tert butyl ester hydrochloride 27532-96-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2023-02-13