Description
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tert-Butyl acetoacetate

Description
Product Name
tert-Butyl acetoacetate
CAS No.
1694-31-1
Chemical Name
tert-Butyl acetoacetate
Synonyms
TBAA;tert-Butyl 3-oxobutanoate;ACTB;Beta-actin;T-BUTYL ACETOACETATE;bact;actba;bactzf;bactin1;CEDI-002
CBNumber
CB0441030
Molecular Formula
C8H14O3
Formula Weight
158.2
MOL File
1694-31-1.mol
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tert-Butyl acetoacetate Property

Melting point:
-38 °C (lit.)
Boiling point:
71-72 °C/11 mmHg (lit.)
Density 
0.954 g/mL at 25 °C (lit.)
vapor pressure 
79.32Pa at 25℃
refractive index 
n20/D 1.419
Flash point:
150 °F
storage temp. 
-20°C
solubility 
9g/l
form 
Liquid
pka
10.71±0.46(Predicted)
color 
clear
PH
5.7 (9g/l, H2O, 20℃)
explosive limit
1.1%(V)
Water Solubility 
Soluble in water (9g/L).
BRN 
1680303
InChIKey
JKUYRAMKJLMYLO-UHFFFAOYSA-N
LogP
0.67-1.41 at 20℃
CAS DataBase Reference
1694-31-1(CAS DataBase Reference)
NIST Chemistry Reference
Butanoic acid, 3-oxo-, 1,1-dimethylethyl ester(1694-31-1)
EPA Substance Registry System
tert-Butyl acetoacetate (1694-31-1)
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Safety

Risk Statements 
36/37/38
Safety Statements 
24/25
RIDADR 
3272
WGK Germany 
1
TSCA 
Yes
HazardClass 
3.2
PackingGroup 
III
HS Code 
29183000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
537594
Product name
tert-Butyl acetoacetate
Purity
reagent grade, 98%
Packaging
1l
Price
$250
Updated
2024/03/01
Sigma-Aldrich
Product number
537594
Product name
tert-Butyl acetoacetate
Purity
reagent grade, 98%
Packaging
4l
Price
$390
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB1305567
Product name
MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse
Purity
clone 8H10D10, crude ascites, buffered aqueous solution
Packaging
100μL
Price
$473
Updated
2023/01/07
TCI Chemical
Product number
A0816
Product name
tert-Butyl Acetoacetate
Purity
>95.0%(GC)
Packaging
25mL
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
A0816
Product name
tert-Butyl Acetoacetate
Purity
>95.0%(GC)
Packaging
100mL
Price
$38
Updated
2024/03/01
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tert-Butyl acetoacetate Chemical Properties,Usage,Production

Description

Tert-Butyl acetoacetate is a reagent used to acetoacetylate hydroxyl-bearing coatings resins, such as polyesters, acrylics, cellulosics, and epoxies. It can be used as an acetoacetylating reagent in pharmaceutical, agrichemical, and pigment applications. It is used as an intermediate for the syntheses of different organic chemicals. For instance, it may be used to synthesize various acetoacetic acid derivatives, acetoacetates, acetoacetamides, 1-(diethylamino)-2-acetoacetoxypropane, (S)-tert-butyl 3-hydroxybutyrate, benzothiazole β-keto ester derivatives, and 3,4-disubstituted pyrroles.

Chemical Properties

liquid

Uses

Intermediate for the syntheses of different organic chemicals. Product Data Sheet

Uses

tert-Butyl acetoacetate is used as intermediate for the syntheses of different organic chemicals. Raw material in pharmaceutical Industry, In agrochemical industry. Reagent for Acyloin synthesis and ?,β - unsaturated ketones synthesis.

General Description

tert-Butyl acetoacetate (t-BAA) is a cheap and easy to store commercial reagent. Reaction demonstrated that the more hindered tert-butyl acetoacetate (t-BAA, la) is ca.15-20-fold more reactive than the more commonly used methyl or ethyl analogs. It is widely employed as an acetoacetylating reagent.

Flammability and Explosibility

Flammable

Biochem/physiol Actions

β-Actin modulates cell growth, migration and the G-actin pool. Mutations in ACTB leads to pleiotropic developmental disorder.

Purification Methods

Distil it under reduced pressure through a short column. [Lawesson et al. Org Synth Coll Vol V 155 1973, Lawesson et al. Org Synth 42 28 1962, Beilstein 3 IV 1536.] HARMFUL VAPOUR.

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tert-Butyl acetoacetate Suppliers

Dalian Idery Biotechnology Co., Ltd.
Tel
15141125520 15141125520
Fax
0411-66160116
Email
3489496641@qq.com
Country
China
ProdList
193
Advantage
58
Shandong Jincheng Pharmaceutical Group Co.,Ltd.
Tel
0533-5439427 13964385406;
Email
henry.zhang@jinchengpharm.com
Country
China
ProdList
34
Advantage
58
BTC Pharmaceutical CO. Ltd
Tel
0513-0513-68015397 18862996710
Fax
0513-68015394
Email
sales12@btcpharm.com
Country
China
ProdList
692
Advantage
55
Weifang QianJin Fine Chemical Co., Ltd.
Tel
13031698386 18753684562
Fax
0536-8897109
Email
1577399715@qq.COM
Country
China
ProdList
1707
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Beijing Donghualituo Techonlogy Development Co.,Ltd.
Tel
010-88425576
Fax
(+86)-10-88425546
Email
sales@dhltchem.com
Country
China
ProdList
793
Advantage
59
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from tert-Butyl acetoacetate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Tert-Butyl Acetoacetate 1694-31-1
Price
US $99.00-45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-12-05
hebei hongtan Biotechnology Co., Ltd
Product
tert-Butyl acetoacetate 1694-31-1
Price
US $30.00/kg
Min. Order
1000kg
Purity
98%
Supply Ability
2000kg
Release date
2024-03-22
Hebei Weibang Biotechnology Co., Ltd
Product
tert-Butyl acetoacetate 1694-31-1
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-29

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