ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE

Application

Product Name: ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE
CAS No.: 43088-42-2
Chemical Name: ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE
Synonyms: methyl 2-amino-4-methylthiophene-3-carboxylate;BUTTPARK 29\08-49;2-aMino-4-Methylthiophene-3-carboxylate;2-Amino-3-(ethoxycarbonyl)-4-methylthiophene;thyl 2-amino-4-methylthiophene-3-carboxylate;Ethyl 2-amino-4-methyl-3-thiophenecarboxylate;ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE;Eethyl 2-amino-4-methylthiophene-3-carboxylate;2-aMino-5-ethyl-4-Methylthiophene-3-carboxylate;Ethyl 2-Amino-4-methylthiophene-3-carboxylate >
CBNumber: CB1241998
Molecular Formula: C8H11NO2S
Formula Weight: 185.24
MOL File: 43088-42-2.mol

More

Less

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE Property

Melting point:: 80 °C
Boiling point:: 279℃
Density: 1.219
Flash point:: 123℃
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Water Solubility: Soluble in water
form: powder to crystal
pka: 0.24±0.10(Predicted)
color: Light yellow to Yellow to Orange
BRN: 1366073
InChI: InChI=1S/C8H11NO2S/c1-3-11-8(10)6-5(2)4-12-7(6)9/h4H,3,9H2,1-2H3
InChIKey: ILYCZKOBLRJJSW-UHFFFAOYSA-N
SMILES: C1(N)SC=C(C)C=1C(OCC)=O
CAS DataBase Reference: 43088-42-2(CAS DataBase Reference)

More

Less

Safety

Safety Statements: 24/25
HazardClass: IRRITANT
HS Code: 29349990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: E1103
Product name: Ethyl 2-Amino-4-methylthiophene-3-carboxylate
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $32
Updated: 2025/07/31

TCI Chemical

Product number: E1103
Product name: Ethyl 2-Amino-4-methylthiophene-3-carboxylate
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $150
Updated: 2025/07/31

TRC

Product number: E899578
Product name: Ethyl 2-Amino-4-methylthiophene-3-carboxylate
Packaging: 1g
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 062874
Product name: Ethyl 2-amino-4-methylthiophene-3-carboxylate
Packaging: 5g
Price: $78
Updated: 2021/12/16

AK Scientific

Product number: X0323
Product name: Ethyl 2-Amino-4-methylthiophene-3-carboxylate
Packaging: 10g
Price: $86
Updated: 2021/12/16

More

Less

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE Chemical Properties,Usage,Production

Application

2-Amino-4-methyl-thiophene-3-carboxylic acid ethyl ester is an ester organic compound that can be used as a pharmaceutical intermediate.

Chemical Properties

Yellow solid

Synthesis

105-56-6

67-64-1

43088-42-2

GENERAL METHOD: Cyclohexanone (1.06 mL, 10 mmol), ethyl cyanoacetate (1.15 mL, 10 mmol), morpholine (0.90 mL, 10 mmol), and sulfur powder (0.32 g, 10 mmol) were dissolved in ethanol (10 mL), and the reaction was stirred and refluxed overnight. After completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by distillation under reduced pressure. The resulting crude product was washed with cold ethanol, filtered through a sintered funnel and dried under vacuum. The dried crude product was dissolved in dichloromethane and washed with saturated saline. The organic layer was separated and concentrated under reduced pressure to afford the target compound ethyl 2-amino-4-methylthiophene-3-carboxylate (2a) in 73% yield (1.83 g).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 13, p. 4418 - 4427
[2] European Journal of Medicinal Chemistry, 2014, vol. 86, p. 270 - 278
[3] Patent: CN107151251, 2017, A. Location in patent: Paragraph 0006; 0010
[4] Organic and Biomolecular Chemistry, 2014, vol. 12, # 24, p. 4233 - 4242
[5] Journal of Molecular Catalysis B: Enzymatic, 2013, vol. 95, p. 29 - 35

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE Preparation Products And Raw materials

Raw materials

tert-Butyl acetoacetate Sulfur Ethanol Morpholine Ethyl cyanoacetate

Preparation Products

More

Less

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE Suppliers

Americas 1 Belgium 1 China 159 Europe 1 Germany 2 India 5 Japan 1 Switzerland 1 United Kingdom 10 United States 18 Global 199

Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd.

Tel: 0515-89701588 13770166955
Fax: 0515-87400189
Email: orgunion@orgunion.com
Country: China
ProdList: 620
Advantage: 55

Suzhou Qiushuo Biotechnology Co., Ltd

Tel: 0512-67862615 13382151840
Email: 2943249291@QQ.COM
Country: China
ProdList: 360
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

More

Less

View Lastest Price from ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE 43088-42-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE 43088-42-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10KG
Release date: 2019-08-05

43088-42-2, ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATERelated Search:

DIETHYL 5-AMINO-3-METHYL-2,4-THIOPHENEDICARBOXYLATE ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE 2-AMINO-4-PHENYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER 2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER ETHYL 2-AMINO-5-METHYLTHIOPHENE-3-CARBOXYLATE 4-METHYLTHIOPHENE-3-CARBOXYLIC ACID Ethyl thiophene-3-carboxylate ETHYL 2-[(2-CHLOROACETYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXYLATE ETHYL 2-AMINO-4-(2-FURYL)THIOPHENE-3-CARBOXYLATE ETHYL 2-AMINO-4-(2-THIENYL)THIOPHENE-3-CARBOXYLATE ethyl 5-acetyl-2-amino-4-methyl-thiophene-3-carboxylate ETHYL 2-ACETAMIDO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE ETHYL 5-AMINO-3-METHYLTHIOPHENE-2-CARBOXYLATE ETHYL 2-[(2,2-DICHLOROACETYL)AMINO]-4-METHYLTHIOPHENE-3-CARBOXYLATE AKOS 89941 ETHYL 2-[2-(2,4-DICHLOROPHENOXY)ACETAMIDO]-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE

BUTTPARK 29\08-49

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE

Ethyl 2-amino-4-methyl-3-thiophenecarboxylate

2-AMINO-4-METHYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER

Ethyl 2-amino-4-methylthiophene-3-carboxylate, 98+%

Ethyl 2-amino-4-methylthiophene-3-carboxylate ,97%

2-Amino-3-(ethoxycarbonyl)-4-methylthiophene

2-aMino-4-Methylthiophene-3-carboxylate

2-aMino-5-ethyl-4-Methylthiophene-3-carboxylate

2-amino-4-methyl-3-thiophenecarboxylic acid ethyl ester

3-thiophenecarboxylic acid, 2-amino-4-methyl-, ethyl ester

methyl 2-amino-4-methylthiophene-3-carboxylate

2-Amino-3-(ethoxycarbonyl)-4-methylthiophene, Ethyl 2-amino-4-methyl-3-thenoate

thyl 2-amino-4-methylthiophene-3-carboxylate

Ethyl 2-Amino-4-methylthiophene-3-carboxylate &gt

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE ISO 9001：2015 REACH

Eethyl 2-amino-4-methylthiophene-3-carboxylate

43088-42-2

Thiophene