ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE
- Product Name
- ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE
- CAS No.
- 4815-24-1
- Chemical Name
- ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE
- Synonyms
- AKOS 92580;AURORA 4294;AKOS B000515;AKOS MSC-0423;Ethyl 2-aMino-4;BUTTPARK 30\06-10;AKOS BBS-00002580;IFLAB-BB F0777-0822;ART-CHEM-BB B000515;TIMTEC-BB SBB005519
- CBNumber
- CB2721222
- Molecular Formula
- C9H13NO2S
- Formula Weight
- 199.27
- MOL File
- 4815-24-1.mol
ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE Property
- Melting point:
- 90 °C
- Boiling point:
- 302.9±37.0 °C(Predicted)
- Density
- 1.185±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 0.56±0.10(Predicted)
- color
- White to Light yellow
- λmax
- 310nm(MeOH)(lit.)
- InChI
- InChI=1S/C9H13NO2S/c1-4-12-9(11)7-5(2)6(3)13-8(7)10/h4,10H2,1-3H3
- InChIKey
- JYSDXODDWAQWJR-UHFFFAOYSA-N
- SMILES
- C1(N)SC(C)=C(C)C=1C(OCC)=O
- CAS DataBase Reference
- 4815-24-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25
- HazardClass
- IRRITANT
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- TMT00191
- Product name
- Ethyl 2-amino-4,5-dimethylthiophene-3-carboxylate
- Packaging
- 1g
- Price
- $443
- Updated
- 2023/06/20
- Product number
- E1005
- Product name
- Ethyl 2-Amino-4,5-dimethylthiophene-3-carboxylate
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $270
- Updated
- 2025/07/31
- Product number
- E1005
- Product name
- Ethyl 2-Amino-4,5-dimethylthiophene-3-carboxylate
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $1008
- Updated
- 2025/07/31
- Product number
- 448835
- Product name
- Ethyl 2-amino-4-
- Packaging
- 100mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- A605165
- Product name
- 2-Amino-4,5-dimethyl-3-thiophenecarboxylicAcidEthylEster
- Packaging
- 25g
- Price
- $495
- Updated
- 2021/12/16
ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE Chemical Properties,Usage,Production
Chemical Properties
Yellow solid
Uses
2-Amino-4,5-dimethyl-3-thiophenecarboxylic Acid Ethyl Ester is used in the preparation triazine and pyrimidine derivatives as anti-inflammatory and analgesic agents. Also used in the synthesis of antioxidants through heteroaryl amines as well as CB2 cannabinoid receptor partial agonists.
Synthesis
105-56-6
78-93-3
4815-24-1
To a 100-mL round-bottomed flask were added 2-butanone (20 g, 0.28 mol, 1.0 eq.), ethyl cyanoacetate (31.4 g, 0.28 mol, 1.0 eq.), and sulfur powder (8.9 g, 0.28 mol, 1.0 eq.), followed by ethanol as a solvent. Diethylamine (21 g, 0.28 mol, 1.0 eq.) was added dropwise to the above mixture. The reaction system was stirred continuously for 8 hours at room temperature. After completion of the reaction, the reaction mixture was diluted with water and the resulting precipitate was collected by filtration. Purification by ethanol recrystallization afforded ethyl 2-amino-4,5-dimethylthiophene-3-carboxylate as a yellow solid (41 g, 75% yield).
References
[1] Synthetic Communications, 2012, vol. 42, # 16, p. 2367 - 2374
[2] Bulletin of the Korean Chemical Society, 2011, vol. 32, # 6, p. 2091 - 2092
[3] Organic and Biomolecular Chemistry, 2014, vol. 12, # 24, p. 4233 - 4242
[4] Journal of Sulfur Chemistry, 2014, vol. 35, # 3, p. 261 - 269
[5] Journal of Heterocyclic Chemistry, 2014, vol. 51, # SUPPL. 1, p. E216-E221
ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE Suppliers
- Tel
- 0515-89701588 13770166955
- Fax
- 0515-87400189
- orgunion@orgunion.com
- Country
- China
- ProdList
- 620
- Advantage
- 55
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
View Lastest Price from ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE manufacturers
- Product
- ETHYL 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE 4815-24-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10KG
- Release date
- 2019-08-05