3,4-Difluorotoluene
- Product Name
- 3,4-Difluorotoluene
- CAS No.
- 2927-34-6
- Chemical Name
- 3,4-Difluorotoluene
- Synonyms
- 3,4-Difluorobenzene;3,4-DIFLUOROTOLUENE;3,4-Difluorotoluene99%;3,4-Difluorotoluene>3,4-Difluorotoluene 99%;3,4-DIFLUOROTOLUENE 98+%;3.4-Difluoro methyl benzene;1,2-Difluoro-4-methylbenzene;3.4-difluoro-Trifluoromethoxy;Benzene, 1,2-difluoro-4-methyl-
- CBNumber
- CB2256988
- Molecular Formula
- C7H6F2
- Formula Weight
- 128.12
- MOL File
- 2927-34-6.mol
3,4-Difluorotoluene Property
- Boiling point:
- 110-113 °C(lit.)
- Density
- 1.12 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.45(lit.)
- Flash point:
- 77 °F
- storage temp.
- Sealed in dry,Room Temperature
- form
- Liquid
- Specific Gravity
- 1.120
- color
- Colorless to Light yellow
- Water Solubility
- Insoluble in water.
- InChIKey
- FZMPLKVGINKUJZ-UHFFFAOYSA-N
- CAS DataBase Reference
- 2927-34-6(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D4054
- Product name
- 3,4-Difluorotoluene
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $23
- Updated
- 2025/07/31
- Product number
- D4054
- Product name
- 3,4-Difluorotoluene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $72
- Updated
- 2025/07/31
- Product number
- D451613
- Product name
- 3,4-Difluorotoluene
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- D451613
- Product name
- 3,4-Difluorotoluene
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- PC2942
- Product name
- 3,4-Difluorotoluene
- Purity
- 99%
- Packaging
- 5g
- Price
- $37
- Updated
- 2021/12/16
3,4-Difluorotoluene Chemical Properties,Usage,Production
Chemical Properties
colorless to light yellow liqui
Uses
Used as pharmaceutical intermediate.
Synthesis
108-88-3
352-32-9
95-52-3
352-70-5
452-76-6
452-67-5
2927-34-6
The general procedure for the synthesis of p-fluorotoluene, 2-fluorotoluene, 3-fluorotoluene, 2,4-difluorotoluene, 2,5-difluorotoluene, and 1,2-difluoro-4-methylbenzene from toluene is as follows: to a glass reactor equipped with a PTFE-lined magnetic stirring bar connected to a gas scrubber bottle, toluene (0.95-1.14 mmol), acetonitrile (1-2.5 mL/mmol toluene), and a boron trifluoride ethyl ether complex (1.3-1.6 mmol/mmol toluene) were added. mmol toluene), acetonitrile (1-2.5 mL/mmol toluene) and boron trifluoride ethyl ether complex (1.3-1.6 mmol/mmol toluene). The reaction solution was stirred at -25°C for 10-15 minutes, followed by the addition of xenon difluoride (1.2-1.3 mmol/mmol toluene) in batches. The reaction mixture was slowly warmed to 22 °C over 1 h and stirring was continued for 40-60 min. Upon completion of the reaction, hexafluorobenzene was added as an internal standard and the sample was removed for 19F NMR analysis (Method B). The reaction mixture was quenched with saturated aqueous sodium bicarbonate and extracted with dichloromethane (1-2 mL). The organic extract was dried over anhydrous magnesium sulfate and analyzed by 19F NMR and GC/MS (Procedure C). The major products are listed in the table and the remaining products are shown below (GC/MS data).
References
[1] Russian Journal of Organic Chemistry, 2016, vol. 52, # 10, p. 1400 - 1407
[2] Zh. Org. Khim., 2016, vol. 52, # 10, p. 1412 - 1419,8
3,4-Difluorotoluene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,4-Difluorotoluene manufacturers
- Product
- 3,4-Difluorotoluene 2927-34-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-11-28
- Product
- 3,4-Difluorotoluene 2927-34-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 50mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-08
- Product
- 3,4-Difluorotoluene 2927-34-6
- Price
- US $2.00/KG
- Min. Order
- 1g
- Purity
- 98%MIN
- Supply Ability
- ASK
- Release date
- 2020-01-07