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2-Fluorotoluene

Product Name
2-Fluorotoluene
CAS No.
95-52-3
Chemical Name
2-Fluorotoluene
Synonyms
O-FLUOROTOLUENE;1-Fluoro-2-methylbenzene;FC6H4CH3;o-Fluortoluol;2-Fluortoluol;o-fluoro-toluen;2-FLUOROTOLUENE;2-fulorotoluene;o-Flouorotoluene;2-FLUOROTOLOUENE
CBNumber
CB8664172
Molecular Formula
C7H7F
Formula Weight
110.13
MOL File
95-52-3.mol
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2-Fluorotoluene Property

Melting point:
-62 °C (lit.)
Boiling point:
113-114 °C (lit.)
Density 
1.001 g/mL at 25 °C (lit.)
vapor density 
3.8 (vs air)
vapor pressure 
21 mm Hg ( 20 °C)
refractive index 
n20/D 1.473(lit.)
Flash point:
55 °F
storage temp. 
Store below +30°C.
form 
Liquid
Specific Gravity
1.001
color 
Clear colorless to slightly yellow
explosive limit
1.3%(V)
Water Solubility 
immiscible
Merck 
14,4180
BRN 
1853362
Dielectric constant
4.2199999999999998
InChI
1S/C7H7F/c1-6-4-2-3-5-7(6)8/h2-5H,1H3
InChIKey
MMZYCBHLNZVROM-UHFFFAOYSA-N
SMILES
Cc1ccccc1F
LogP
2.73-2.74
CAS DataBase Reference
95-52-3(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-fluoro-2-methyl-(95-52-3)
EPA Substance Registry System
o-Fluorotoluene (95-52-3)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-36/37/38
Safety Statements 
16-26-33-36-37/39
RIDADR 
UN 2388 3/PG 2
WGK Germany 
3
RTECS 
XT2579000
Hazard Note 
Flammable/Irritant
TSCA 
TSCA listed
HazardClass 
3
PackingGroup 
II
HS Code 
29036990
Storage Class
3 - Flammable liquids
Hazard Classifications
Flam. Liq. 2
STOT SE 3
Toxicity
LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 2000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F15323
Product name
2-Fluorotoluene
Purity
≥99%
Packaging
100g
Price
$60.1
Updated
2025/07/31
Sigma-Aldrich
Product number
F15323
Product name
2-Fluorotoluene
Purity
≥99%
Packaging
500g
Price
$146
Updated
2025/07/31
TCI Chemical
Product number
F0039
Product name
2-Fluorotoluene
Purity
>99.0%(GC)
Packaging
25mL
Price
$16
Updated
2025/07/31
TCI Chemical
Product number
F0039
Product name
2-Fluorotoluene
Purity
>99.0%(GC)
Packaging
500mL
Price
$86
Updated
2025/07/31
Strem Chemicals
Product number
09-4310
Product name
o-Fluorotoluene, 99%
Packaging
50g
Price
$31
Updated
2024/03/01
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2-Fluorotoluene Chemical Properties,Usage,Production

Chemical Properties

clear colorless to slightly yellow liquid

Uses

It is employed in organic synthesis.

General Description

A colorless liquid with an aromatic odor. May sink or float on water.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

2-Fluorotoluene is of generally low reactivity. Reacts with strong oxidizing agents and strong reducing agents. Also may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides [USCG, 1999].

Health Hazard

Inhalation of vapor may cause respiratory irritation. Prolonged and repeated vapor exposures may produce systemic toxic effects.

Synthesis

The halogen exchange method reacts aromatic compounds with alkali metal fluorides (e.g., CsF and KF, etc.) and substituent groups, allowing the fluorine atom to replace other halogen groups (e.g., chlorine). The reaction method of halogen exchange between inorganic halides and between organic halides is known as the Finkelstein method. It is one of the most widely used methods for synthesizing fluoroaromatic compounds in industrial production, and has been one of the more active areas in the synthesis of fluoroaromatic compounds in recent years. Halogen exchange method is the main method with industrialized application value, characterized by low price of raw materials, easy to obtain and good selectivity, and in the reaction process can not use fluoroboric acid, hydrogen fluoride and other highly toxic reagents, in general, relatively environmentally friendly and safe, in line with the trend of the development of pharmaceutical pesticides nowadays. The disadvantage is that its reaction conditions are relatively harsh, requiring reaction at higher temperatures and under the condition of excess potassium fluoride, and also requiring the use of non-protonic inert reagents as solvents, and need to be carried out under the condition of anhydrous.

Purification Methods

Dry o-fluorotoluene with P2O5 or CaSO4 and fractionally distil it through a silvered vacuum-jacketed glass column with 1/8th-in glass helices. A high reflux ratio is necessary because of the closeness of the boiling points of the o-, m-and p-isomers [Potter & Saylor J Am Chem Soc 37 90 1951]. [Beilstein 5 H 290, 5 III 676, 5 IV 799.]

2-Fluorotoluene Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Fluorotoluene Suppliers

Jiangsu Nengyue New Materials Technology Co., Ltd
Tel
13376001577
Email
615731430@qq.com
Country
China
ProdList
325
Advantage
58
Yancheng Huahong Chemical Co., Ltd.
Tel
15366451979
Email
sales@huahongchem.com
Country
China
ProdList
24
Advantage
58
Shandong Aite Chemical Co., Ltd
Tel
18615658326
Email
18615658326@163.com
Country
China
ProdList
58
Advantage
58
Shandong Jiuyue Biological Technology Co. LT
Tel
18853316981
Email
1214127295@qq.com
Country
China
ProdList
204
Advantage
58
Nanjing Deweiqi Chemical Technology Co., Ltd
Tel
18652911584
Email
381854775@qq.com
Country
China
ProdList
310
Advantage
58
Dexin chemical (Shandong) Co. , Ltd.
Tel
18815338815
Email
dexinhuaxue@163.com
Country
China
ProdList
149
Advantage
58
AnDaChenxiang ChemicalCo., Ltd.
Tel
0455-7669909 18746673231
Email
2035411054@qq.com
Country
China
ProdList
17
Advantage
58
Yancheng Green Fluorine Fine Chemical Trading Co., Ltd
Tel
17887358129
Email
lvfu@163.cn
Country
China
ProdList
29
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from 2-Fluorotoluene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Fluorotoluene 95-52-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-21
Shaanxi Dideu Medichem Co. Ltd
Product
2-Fluorotoluene 95-52-3
Price
US $0.00-0.00/KG
Min. Order
50mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-08
Hebei Zhanyao Biotechnology Co. Ltd
Product
2-Fluorotoluene 95-52-3
Price
US $10.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2021-11-19

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