2-Fluorobenzylamine
- Product Name
- 2-Fluorobenzylamine
- CAS No.
- 89-99-6
- Chemical Name
- 2-Fluorobenzylamine
- Synonyms
- (2-Fluorophenyl)methanamine;FluorobenzylaMines;2-FLUOROBENZYLAMINE;O-FLUOROBENZYLAMINE;RARECHEM AL BW 0009;Benzylamine, o-fluoro-;2-Fluorobenzylamine>2-Fluorobenzylamine,97%;ortho-Fluorobenzylamine;2-Fluorobenzylamine 97%
- CBNumber
- CB8724346
- Molecular Formula
- C7H8FN
- Formula Weight
- 125.14
- MOL File
- 89-99-6.mol
2-Fluorobenzylamine Property
- Melting point:
- 245-246 °C(Solv: N,N-dimethylformamide (68-12-2))
- Boiling point:
- 73-75 °C13 mm Hg(lit.)
- Density
- 1.095 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.517(lit.)
- Flash point:
- 153 °F
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 8?+-.0.10(Predicted)
- form
- Liquid
- Specific Gravity
- 1.095
- color
- Clear colorless to yellow
- Sensitive
- Air Sensitive
- BRN
- 508109
- CAS DataBase Reference
- 89-99-6(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenemethanamine, 2-fluoro-(89-99-6)
- EPA Substance Registry System
- Benzenemethanamine, 2-fluoro- (89-99-6)
Safety
- Hazard Codes
- C,Xi,T
- Risk Statements
- 34-20/21/22
- Safety Statements
- 26-27-36/37/39-45
- RIDADR
- UN 2735 8/PG 2
- WGK Germany
- 3
- Hazard Note
- Irritant
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29214990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H227Combustible liquid
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F0538
- Product name
- 2-Fluorobenzylamine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $49
- Updated
- 2025/07/31
- Product number
- F0538
- Product name
- 2-Fluorobenzylamine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $149
- Updated
- 2025/07/31
- Product number
- F596725
- Product name
- 2-Fluorobenzylamine
- Packaging
- 2.5g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 3630-3-32
- Product name
- 2-Fluorobenzylamine
- Purity
- 97%
- Packaging
- 100g
- Price
- $119
- Updated
- 2021/12/16
- Product number
- 006197
- Product name
- 2-Fluorobenzylamine
- Purity
- 97%
- Packaging
- 100g
- Price
- $120
- Updated
- 2021/12/16
2-Fluorobenzylamine Chemical Properties,Usage,Production
Chemical Properties
clear colorless to yellow liquid
Uses
2-Fluorobenzylamine was used in synthesis of 9-(2-fluorobenzyl)-6-(methylamino)-9H-purine, having anticonvulsant activity. It was also used in synthesis and study of structure-activity relationship of a series of substituted spirohydantoins.
Synthesis
394-47-8
89-99-6
General procedure for the synthesis of 2-fluorobenzylamine from 2-fluorobenzonitrile: the standard method for the reduction of nitrile by KBH4 and CuCl2 was used. The procedure was as follows: 2-fluorobenzonitrile (0.15 g, 1 mmol), KBH4 (0.17 g, 3 mmol), CuCl2 (0.03 g, 0.25 mmol), and 80% isopropanol solution (1.6 mL of isopropanol and 0.4 mL of water) were added to a 10 mL round-bottom flask. The reaction was carried out at 60 °C and the progress of the reaction was monitored by TLC (unfolding agent ratio of DCM:MeOH 10:1) to confirm that the reaction was completed within 8 hours. Upon completion of the reaction, the mixture was cooled to 25 °C and the solvent was subsequently removed under reduced pressure. Ethyl acetate (5 mL) was added to the residue and washed sequentially with water (1 mL) and saturated saline (1 mL). The organic layer was dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure to give the crude product 2-fluorobenzylamine.
References
[1] Journal of the American Chemical Society, 2015, vol. 137, # 28, p. 8888 - 8891
[2] Synlett, 2001, # 10, p. 1623 - 1625
[3] Small, 2018, vol. 14, # 37,
[4] ChemCatChem, 2017, vol. 9, # 4, p. 559 - 563
[5] Asian Journal of Chemistry, 2015, vol. 27, # 10, p. 3564 - 3566
2-Fluorobenzylamine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Fluorobenzylamine Suppliers
- Tel
- 18014482516; 18014482516
- 977144864@qq.com
- Country
- China
- ProdList
- 419
- Advantage
- 58
- Tel
- 13585203734
- info@jbzml.com
- Country
- China
- ProdList
- 99
- Advantage
- 58
- Tel
- 86-27-82330560
- Fax
- 86-27-82330547
- 2536851935@qq.com
- Country
- China
- ProdList
- 347
- Advantage
- 69
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- +86 351 7031519
- Fax
- +86 351 7031519
- sales@RHFChem.com
- Country
- China
- ProdList
- 2338
- Advantage
- 56
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
View Lastest Price from 2-Fluorobenzylamine manufacturers
- Product
- 2-Fluorobenzylamine 89-99-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 300mt
- Release date
- 2021-11-08
- Product
- 2-Fluorobenzylamine 89-99-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.1%
- Supply Ability
- 100 tons
- Release date
- 2022-02-18
- Product
- 2-Fluorobenzylamine 89-99-6
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-20