2'-Fluoroacetanilide

Product Name: 2'-Fluoroacetanilide
CAS No.: 399-31-5
Chemical Name: 2'-Fluoroacetanilide
Synonyms: 2-FLUOROACETANILINE;2-FLUOROACETANILIDE;O-FLUOROACETANILIDE;2'-Fluoroacetanilide;2'-Fluoroacetanilide>Flurbiprofen Impurity 23;N-Acetyl 2-fluoroaniline;2-Fluorophenyl acetamide;2-Fluoroacetanilide, 98+%;N-(2-Fluorphenyl)acetamid
CBNumber: CB7776328
Molecular Formula: C8H8FNO
Formula Weight: 153.15
MOL File: 399-31-5.mol

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2'-Fluoroacetanilide Property

Melting point:: 77-79 °C(lit.)
Boiling point:: 140-142 °C14 mm Hg(lit.)
Density: 1.1655 (estimate)
Flash point:: 140-142°C/14mm
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
pka: 14.04±0.70(Predicted)
form: Fine Crystalline Powder
color: White
BRN: 2717443
CAS DataBase Reference: 399-31-5(CAS DataBase Reference)
NIST Chemistry Reference: Acetamide, N-(2-fluorophenyl)-(399-31-5)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29242998

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: F0524
Product name: 2'-Fluoroacetanilide
Purity: >98.0%(GC)
Packaging: 25g
Price: $53
Updated: 2025/07/31

TRC

Product number: F587065
Product name: 2''-Fluoroacetanilide
Packaging: 500mg
Price: $45
Updated: 2021/12/16

TRC

Product number: F587065
Product name: 2''-Fluoroacetanilide
Packaging: 5g
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4648-3-02
Product name: 2-Fluoroacetanilide
Purity: 98%
Packaging: 5G
Price: $15
Updated: 2021/12/16

AK Scientific

Product number: J97987
Product name: 2'-Fluoroacetanilide
Packaging: 25g
Price: $18
Updated: 2021/12/16

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2'-Fluoroacetanilide Chemical Properties,Usage,Production

Chemical Properties

white fine crystalline powder

Uses

2''-Fluoroacetanilide

Synthesis

348-54-9

108-24-7

399-31-5

Step 1: Synthesis of N-(2-fluorophenyl)acetamide To a solution of 2-fluoroaniline (5.0 g, 45.05 mmol) in dichloromethane (DCM, 225 mL) was sequentially added acetic anhydride (4.09 mL, 45.05 mmol) and triethylamine (7.55 mL, 54.05 mmol). The reaction mixture was stirred at room temperature for 6 hours. After completion of the reaction, the mixture was concentrated, diluted with ethyl acetate and washed with 1N hydrochloric acid (2 x 50 mL). The organic phase was dried with anhydrous sodium sulfate (Na2SO4) and concentrated to give N-(2-fluorophenyl)acetamide (6.20 g, 90% yield) as a white solid.LCMS analysis showed the molecular ion peak of the target product to be 153.99 (M + H)+.

References

[1] Journal of Medicinal Chemistry, 2003, vol. 46, # 11, p. 2187 - 2196
[2] Patent: US2008/139558, 2008, A1. Location in patent: Page/Page column 80
[3] Journal of the Chemical Society - Perkin Transactions 1, 1996, # 7, p. 669 - 673
[4] Patent: US2012/238543, 2012, A1. Location in patent: Page/Page column 13
[5] Patent: US2012/270854, 2012, A1. Location in patent: Page/Page column 20

2'-Fluoroacetanilide Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-Fluoroacetanilide Suppliers

Americas 1 Belgium 2 Canada 1 China 84 Europe 3 France 2 Germany 3 India 6 Italy 1 Japan 3 Slovakia 1 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 12 United States 32 Global 154

J & K SCIENTIFIC LTD.

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Alfa Aesar

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Shanghai Jian Chao Chemical Technology Co., Ltd.

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View Lastest Price from 2'-Fluoroacetanilide manufacturers

Honest Joy Holdings Limited

Product: 2'-Fluoroacetanilide 399-31-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.1%
Supply Ability: 100 tons
Release date: 2022-01-14

Career Henan Chemical Co

Product: 2'-Fluoroacetanilide 399-31-5
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-14

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2'-Fluoroacetanilide

2′-Fluoroacetanilide, CAS 399-31-5

399-31-5

Building Blocks

Protected Amines

Organic Building Blocks

Nitrogen Compounds

Anilines, Amides & Amines

Fluorine Compounds

Nitrogen Compounds

Organic Building Blocks

Protected Amines

blocks

BuildingBlocks

FluoroCompounds

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts