ChemicalBook > CAS DataBase List > 3,4-Difluorotoluene

3,4-Difluorotoluene

Product Name
3,4-Difluorotoluene
CAS No.
2927-34-6
Chemical Name
3,4-Difluorotoluene
Synonyms
3,4-Difluorobenzene;3,4-DIFLUOROTOLUENE;3,4-Difluorotoluene99%;3,4-Difluorotoluene>3,4-Difluorotoluene 99%;3,4-DIFLUOROTOLUENE 98+%;3.4-Difluoro methyl benzene;1,2-Difluoro-4-methylbenzene;3.4-difluoro-Trifluoromethoxy;Benzene, 1,2-difluoro-4-methyl-
CBNumber
CB2256988
Molecular Formula
C7H6F2
Formula Weight
128.12
MOL File
2927-34-6.mol
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3,4-Difluorotoluene Property

Boiling point:
110-113 °C(lit.)
Density 
1.12 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.45(lit.)
Flash point:
77 °F
storage temp. 
Sealed in dry,Room Temperature
form 
Liquid
Specific Gravity
1.120
color 
Colorless to Light yellow
Water Solubility 
Insoluble in water.
InChIKey
FZMPLKVGINKUJZ-UHFFFAOYSA-N
CAS DataBase Reference
2927-34-6(CAS DataBase Reference)
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Safety

Hazard Codes 
F
Risk Statements 
10
Safety Statements 
16-29-33
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
Hazard Note 
Flammable
HazardClass 
3
PackingGroup 
II
HS Code 
29039990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D4054
Product name
3,4-Difluorotoluene
Purity
>98.0%(GC)
Packaging
1g
Price
$23
Updated
2025/07/31
TCI Chemical
Product number
D4054
Product name
3,4-Difluorotoluene
Purity
>98.0%(GC)
Packaging
5g
Price
$72
Updated
2025/07/31
TRC
Product number
D451613
Product name
3,4-Difluorotoluene
Packaging
5g
Price
$75
Updated
2021/12/16
TRC
Product number
D451613
Product name
3,4-Difluorotoluene
Packaging
1g
Price
$55
Updated
2021/12/16
Apolloscientific
Product number
PC2942
Product name
3,4-Difluorotoluene
Purity
99%
Packaging
5g
Price
$37
Updated
2021/12/16
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3,4-Difluorotoluene Chemical Properties,Usage,Production

Chemical Properties

colorless to light yellow liqui

Uses

Used as pharmaceutical intermediate.

Synthesis

108-88-3

352-32-9

95-52-3

352-70-5

452-76-6

452-67-5

2927-34-6

The general procedure for the synthesis of p-fluorotoluene, 2-fluorotoluene, 3-fluorotoluene, 2,4-difluorotoluene, 2,5-difluorotoluene, and 1,2-difluoro-4-methylbenzene from toluene is as follows: to a glass reactor equipped with a PTFE-lined magnetic stirring bar connected to a gas scrubber bottle, toluene (0.95-1.14 mmol), acetonitrile (1-2.5 mL/mmol toluene), and a boron trifluoride ethyl ether complex (1.3-1.6 mmol/mmol toluene) were added. mmol toluene), acetonitrile (1-2.5 mL/mmol toluene) and boron trifluoride ethyl ether complex (1.3-1.6 mmol/mmol toluene). The reaction solution was stirred at -25°C for 10-15 minutes, followed by the addition of xenon difluoride (1.2-1.3 mmol/mmol toluene) in batches. The reaction mixture was slowly warmed to 22 °C over 1 h and stirring was continued for 40-60 min. Upon completion of the reaction, hexafluorobenzene was added as an internal standard and the sample was removed for 19F NMR analysis (Method B). The reaction mixture was quenched with saturated aqueous sodium bicarbonate and extracted with dichloromethane (1-2 mL). The organic extract was dried over anhydrous magnesium sulfate and analyzed by 19F NMR and GC/MS (Procedure C). The major products are listed in the table and the remaining products are shown below (GC/MS data).

References

[1] Russian Journal of Organic Chemistry, 2016, vol. 52, # 10, p. 1400 - 1407
[2] Zh. Org. Khim., 2016, vol. 52, # 10, p. 1412 - 1419,8

3,4-Difluorotoluene Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-Difluorotoluene Suppliers

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View Lastest Price from 3,4-Difluorotoluene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
3,4-Difluorotoluene 2927-34-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-28
Shaanxi Dideu Medichem Co. Ltd
Product
3,4-Difluorotoluene 2927-34-6
Price
US $0.00-0.00/KG
Min. Order
50mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-08
Career Henan Chemical Co
Product
3,4-Difluorotoluene 2927-34-6
Price
US $2.00/KG
Min. Order
1g
Purity
98%MIN
Supply Ability
ASK
Release date
2020-01-07

2927-34-6, 3,4-DifluorotolueneRelated Search:


  • 3,4-DIFLUOROTOLUENE
  • 3,4-Difluorobenzene
  • 3,4-Difluorotoluene 99%
  • 3.4-Difluoro methyl benzene
  • 3,4-Difluorotoluene99%
  • 3,4-DIFLUOROTOLUENE 98+%
  • 1,2-Difluoro-4-methylbenzene
  • 3.4-difluoro-Trifluoromethoxy
  • 3,4-Difluorotoluene&gt
  • Benzene, 1,2-difluoro-4-methyl-
  • 2927-34-6
  • 2927-34-7
  • C7H6F2
  • Organic Building Blocks
  • Halogenated Hydrocarbons
  • Building Blocks
  • Aryl
  • C7
  • Aromatic Hydrocarbons (substituted) & Derivatives
  • Halogen toluene
  • Miscellaneous
  • Aryl
  • C7
  • Halogenated Hydrocarbons
  • Fluorinated benzene series
  • Fluorin-contained toluene series