Methyl 3-AMino-5-broMo-2-Methylbenzoate
- Product Name
- Methyl 3-AMino-5-broMo-2-Methylbenzoate
- CAS No.
- 1000342-11-9
- Chemical Name
- Methyl 3-AMino-5-broMo-2-Methylbenzoate
- Synonyms
- 3-amino-5-bromo-2-methylbenzoic acid;EOS-61052;Benzoic acid, 3-aMino-5-b...;Methyl 3-AMino-5-broMo-2-Methylbenzoate;MethyI 3-AMino-5-broMo-2-Methylbenzoate;3-Amino-2-Methyl-5-bromo benzoic acid methyl este;3-AMino-5-broMo-2-Methyl-benzoicacid Methyl ester;Benzoic acid, 3-aMino-5-broMo-2-Methyl-, Methyl ester
- CBNumber
- CB22570772
- Molecular Formula
- C9H10BrNO2
- Formula Weight
- 244.09
- MOL File
- 1000342-11-9.mol
Methyl 3-AMino-5-broMo-2-Methylbenzoate Property
- Melting point:
- 52 °C
- Boiling point:
- 336.0±37.0 °C(Predicted)
- Density
- 1.506
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 2.23±0.10(Predicted)
- color
- White to Light yellow to Light orange
- InChI
- InChI=1S/C9H10BrNO2/c1-5-7(9(12)13-2)3-6(10)4-8(5)11/h3-4H,11H2,1-2H3
- InChIKey
- NMLOSXSDLWFBKT-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C1=CC(Br)=CC(N)=C1C
- CAS DataBase Reference
- 1000342-11-9
Safety
- RIDADR
- UN2811
- HS Code
- 2922.49.3700
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M2844
- Product name
- Methyl 3-Amino-5-bromo-2-methylbenzoate
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $37
- Updated
- 2025/07/31
- Product number
- M2844
- Product name
- Methyl 3-Amino-5-bromo-2-methylbenzoate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $112
- Updated
- 2025/07/31
- Product number
- M331430
- Product name
- Methyl 3-Amino-5-bromo-2-methylbenzoate
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- M331430
- Product name
- Methyl 3-Amino-5-bromo-2-methylbenzoate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-M3309
- Product name
- Methyl 3-Amino-5-bromo-2-methylbenzoate
- Purity
- 99.46%
- Packaging
- 25g
- Price
- $50
- Updated
- 2021/12/16
Methyl 3-AMino-5-broMo-2-Methylbenzoate Chemical Properties,Usage,Production
Uses
Methyl 3-amino-5-bromo-2-methylbenzoate is used as an intermediate in organic synthesis and is widely used in the manufacture of pharmaceuticals (e.g., anticancer drugs, antimicrobials and pesticides) and dye products.
Synthesis
220514-28-3
1000342-11-9
General procedure for the synthesis of methyl 2-methyl-3-amino-5-bromobenzoate from methyl 5-bromo-2-methyl-3-nitrobenzoate: methyl 5-bromo-2-methyl-3-nitrobenzoate (17 g, 62 mmol) was dissolved in a mixed solvent of ethanol (150 ml) and water (75 ml), followed by addition of ammonium chloride (17 g, 318 mmol) and iron powder ( 27.8 g, 498 mmol). The reaction mixture was stirred at 90°C for 1 hour. After completion of the reaction, the reaction mixture was filtered while hot and the filtrate was concentrated under vacuum, saturated aqueous sodium bicarbonate solution was added and extracted with ethyl acetate. The organic phases were combined, dried with anhydrous sodium sulfate and subsequently concentrated in vacuum to give 15 g of methyl 2-methyl-3-amino-5-bromobenzoate in 99% yield.
References
[1] Patent: WO2012/118812, 2012, A2. Location in patent: Page/Page column 312
[2] Patent: WO2012/142513, 2012, A1. Location in patent: Page/Page column 268
[3] Patent: US2014/107122, 2014, A1. Location in patent: Paragraph 0161; 0162
[4] Patent: CN105037360, 2016, B. Location in patent: Paragraph 0205; 0206; 0207
[5] Patent: WO2015/104677, 2015, A1. Location in patent: Page/Page column 69
Methyl 3-AMino-5-broMo-2-Methylbenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 3-AMino-5-broMo-2-Methylbenzoate manufacturers
- Product
- Methyl 3-AMino-5-broMo-2-Methylbenzoate 1000342-11-9
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-18
- Product
- Methyl 3-AMino-5-broMo-2-Methylbenzoate 1000342-11-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-08
- Product
- Methyl 3-AMino-5-broMo-2-Methylbenzoate 1000342-11-9
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-15